Search Results - "Oelschlagel, U"

The prognostic impact of 17p ( ) deletion in 2272 adults with acute myeloid leukemia by Seifert, H, Mohr, B, Thiede, C, Oelschlägel, U, Schäkel, U, Illmer, T, Soucek, S, Ehninger, G, Schaich, M

“…Loss of p53 —a tumor suppressor gene located on the short arm of chromosome 17 (band 17p13.1)—was detected in 105 out of 2272 (5%) adult acute myeloid leukemia…”
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P-glycoprotein-mediated drug efflux is a resistance mechanism of chronic myelogenous leukemia cells to treatment with imatinib mesylate by ILLMER, T, SCHAICH, M, PLATZBECKER, U, FREIBERG-RICHTER, J, OELSCHLÄGEL, U, VON BONIN, M, PURSCHE, S, BERGEMANN, T, EHNINGER, G, SCHLEYER, E

“…Imatinib (Glivec), STI571) is an intracellular acting drug that demonstrates high activity against BCR-ABL-positive chronic myelogenous leukemia (CML) or acute…”
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Immunophenotyping of acute leukemia and lymphoproliferative disorders: a consensus proposal of the European LeukemiaNet Work Package 10 by Béné, M C, Nebe, T, Bettelheim, P, Buldini, B, Bumbea, H, Kern, W, Lacombe, F, Lemez, P, Marinov, I, Matutes, E, Maynadié, M, Oelschlagel, U, Orfao, A, Schabath, R, Solenthaler, M, Tschurtschenthaler, G, Vladareanu, A M, Zini, G, Faure, G C, Porwit, A

“…The European LeukemiaNet (ELN), workpackage 10 (WP10) was designed to deal with diagnosis matters using morphology and immunophenotyping. This group aimed at…”
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Durable responses to ibrutinib in patients with relapsed CLL after allogeneic stem cell transplantation by Link, C S, Teipel, R, Heidenreich, F, Rücker-Braun, E, Schmiedgen, M, Reinhardt, J, Oelschlägel, U, von Bonin, M, Middeke, J M, Muetherig, A, Trautmann-Grill, K, Platzbecker, U, Bornhäuser, M, Schetelig, J

“…Ibrutinib, a recently approved inhibitor of Bruton’s tyrosine kinase (BTK), has shown great efficacy in patients with high-risk CLL. Nevertheless, there are…”
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Platelet-Associated Tissue Factor Contributes to the Collagen-Triggered Activation of Blood Coagulation by Zillmann, Andreas, Luther, Thomas, Müller, Ingrid, Kotzsch, Matthias, Spannagl, Michael, Kauke, Teresa, Oelschlägel, Uta, Zahler, Stefan, Engelmann, Bernd

“…The extravascular localization of tissue factor (TF), the central initiator of coagulation, is thought to ensure that thrombus formation is prevented in the…”
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Distribution and levels of cell surface expression of CD33 and CD123 in acute myeloid leukemia by Ehninger, A, Kramer, M, Röllig, C, Thiede, C, Bornhäuser, M, von Bonin, M, Wermke, M, Feldmann, A, Bachmann, M, Ehninger, G, Oelschlägel, U

“…Owing to the more recent positive results with the anti-CD33 immunotoxin gemtuzumab ozogamicin, therapy against acute myeloid leukemias (AMLs) targeting CD33…”
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Dose-reduced Conditioning and Allogeneic Hematopoietic Stem Cell Transplantation from Unrelated Donors in 42 Patients by Martin Bornhäuser, Christian Thiede, Uwe Platzbecker, Andreas Jenke, Anett Helwig, Runa Plettig, Jens Freiberg-Richter, Christoph Röllig, Gabriele Geissler, Karin Lutterbeck, Uta Oelschlagel, Gerhard Ehninger

“…Purpose : A fludarabine-based “nonmyeloablative” preparative regimen was investigated in 42 patients with hematological malignancies receiving hematopoietic…”
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T cell receptor repertoires after adoptive transfer of expanded allogeneic regulatory T cells by Theil, A., Wilhelm, C., Kuhn, M., Petzold, A., Tuve, S., Oelschlägel, U., Dahl, A., Bornhäuser, M., Bonifacio, E., Eugster, A.

“…Summary Regulatory T cell (Treg) therapy has been exploited in autoimmune disease, solid organ transplantation and in efforts to prevent or treat…”
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Abundant cytomegalovirus (CMV) reactive clonotypes in the CD8+ T cell receptor alpha repertoire following allogeneic transplantation by Link, C. S., Eugster, A., Heidenreich, F., Rücker‐Braun, E., Schmiedgen, M., Oelschlägel, U., Kühn, D., Dietz, S., Fuchs, Y., Dahl, A., Domingues, A. M. J., Klesse, C., Schmitz, M., Ehninger, G., Bornhäuser, M., Schetelig, J., Bonifacio, E.

“…Summary Allogeneic stem cell transplantation is potentially curative, but associated with post‐transplantation complications, including cytomegalovirus (CMV)…”
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Karyotype complexity and prognosis in acute myeloid leukemia by Stölzel, F, Mohr, B, Kramer, M, Oelschlägel, U, Bochtler, T, Berdel, W E, Kaufmann, M, Baldus, C D, Schäfer-Eckart, K, Stuhlmann, R, Einsele, H, Krause, S W, Serve, H, Hänel, M, Herbst, R, Neubauer, A, Sohlbach, K, Mayer, J, Middeke, J M, Platzbecker, U, Schaich, M, Krämer, A, Röllig, C, Schetelig, J, Bornhäuser, M, Ehninger, G

“…A complex aberrant karyotype consisting of multiple unrelated cytogenetic abnormalities is associated with poor prognosis in patients with acute myeloid…”
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Evolution of NPM1-negative therapy-related myelodysplastic syndromes following curative treatment of NPM1-mutant AML by Herold, S, Sockel, K, Sayehli, C, Herbst, R, Dührsen, U, Oelschlägel, U, Böttner, A, Hindahl, H, Kullmer, J, Helas, S, Sauer, M, Mohr, B, Mies, A, Bornhäuser, M, Ehninger, G, Röllig, C, Thiede, C, Platzbecker, U

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Hematopoietic cell transplantation in patients with intermediate and high-risk AML: results from the randomized Study Alliance Leukemia (SAL) AML 2003 trial by Schetelig, J, Schaich, M, Schäfer-Eckart, K, Hänel, M, Aulitzky, W E, Einsele, H, Schmitz, N, Rösler, W, Stelljes, M, Baldus, C D, Ho, A D, Neubauer, A, Serve, H, Mayer, J, Berdel, W E, Mohr, B, Oelschlägel, U, Parmentier, S, Röllig, C, Kramer, M, Platzbecker, U, Illmer, T, Thiede, C, Bornhäuser, M, Ehninger, G

“…The optimal timing of allogeneic hematopoietic stem cell transplantation (HCT) in acute myeloid leukemia (AML) is controversial. We report on 1179 patients…”
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Mesenchymal Stromal Cell-Derived Extracellular Vesicles are Altered in MDS by Wobus, M, Mies, A, Yilmaz, D, Oelschlägel, U, Kahlert, C, Bornhäuser, M, Platzbecker, U

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Risk stratification using a new prognostic score for patients with secondary acute myeloid leukemia: results of the prospective AML96 trial by Stölzel, F, Pfirrmann, M, Aulitzky, W E, Kaufmann, M, Bodenstein, H, Bornhäuser, M, Röllig, C, Kramer, M, Mohr, B, Oelschlägel, U, Schmitz, N, Soucek, S, Thiede, C, Ehninger, G, Schaich, M

“…Patients with secondary acute myeloid leukemia (sAML) are generally thought to have a poor prognosis. As there are no prognostic risk stratification models for…”
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P752: TARGETING S100A9 IN THE MYELODYSPLASTIC INFLAMMATORY BONE MARROW MICROENVIRONMENT BY TASQUINIMOD IMPROVES THE SUPPORTIVE FUNCTION OF MESENCHYMAL STROMAL CELLS by Wobus, M., Balaian, E., Lissner, M., Towers, R., Oelschlägel, U., Wehner, R., Chavakis, T., Törngren, M., Eriksson, H., Bondesson, E., Platzbecker, U., Bornhäuser, M., Sockel, K.

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Some limitations in the detection of residual aneuploid cells with dna quantification on immunophenotyped cells by flow cytometry by Nowak, Ralf, Oelschlägel, Uta, Heider, Torsten, Naumann, Ralph, Ehninger, Gerhard

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P449: NOVEL, FIRST‐IN‐CLASS, SOMATIC IDH2 DELETION‐INSERTION VARIANT C.516_518DELINSTGC CONFERS BORDERLINE PHENOTYPE AND DOES NOT SHOW SUSCEPTIBILITY TO ENASIDENIB IN‐VITRO by Ruhnke, L., Poitz, D. M., Herold, S., Dressler, S., Dill, C., Peitzsch, M., Oelschlägel, U., Frimmel, J., Kunadt, D., Kretschmann, T., Altmann, H., Stölzel, F., Röllig, C., Chavakis, T., Baretton, G., Schäfer‐Eckart, K., Bornhäuser, M.

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Sequential monitoring of chimerism and detection of minimal residual disease after allogeneic blood stem cell transplantation (BSCT) using multiplex PCR amplification of short tandem repeat-markers by THIEDE, C, BORNHÄUSER, M, NAUMANN, R, RITTER, M, PRANGE-KREX, G, LION, T, NEUBAUER, A, EHNINGER, G, OELSCHLÄGEL, U, BRENDEL, C, LEO, R, DAXBERGER, H, MOHR, B, FLOREK, M, KROSCHINSKY, F, GEISSLER, G

“…Sequential analysis of chimerism after allogeneic blood stem cell transplantation (BSCT) has been shown to be predictive for graft failure and relapse. We have…”
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Regulatory T cell kinetics following adoptive transfer of expanded allogeneic regulatory T cells into patients with chronic graft-versus host disease by Fuchs (Theil), A, Wilhelm, C, Kuhn, M, Petzold, A, Tuve, S, Oelschlägel, U, Dahl, A, Bornhäuser, M, Bonifacio, E, Eugster, A

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A new PCR MIMIC strategy to quantify low mdr1 mRNA levels in drug resistant cell lines and AML blast samples by Illmer, Thomas, Schaich, Markus, Oelschlägel, Uta, Nowak, Ralf, Renner, Ulf, Ziegs, Barbara, Subat, Sabine, Neubauer, Andreas, Ehninger, Gerhard

“…Determination of the MDR-phenotype in patients suffering from AML is an important hallmark of treatment outcome but is often complicated by technical problems…”
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