Search Results - "Oehlke, J"

Shared medical appointments in a pharmacy-based erectile dysfunction clinic by Oehlke, Kelley J, Whitehill, Dawn M

Get full text

Cellular uptake of antisense oligonucleotides after complexing or conjugation with cell‐penetrating model peptides by Oehlke, J., Birth, P., Klauschenz, E., Wiesner, B., Beyermann, M., Oksche, A., Bienert, M.

“…The uptake by mammalian cells of phosphorothioate oligonucleotides was compared with that of their respective complexes or conjugates with cationic,…”
Get full text

Uptake of cell-penetrating peptides is dependent on peptide-to-cell ratio rather than on peptide concentration by Hällbrink, Mattias, Oehlke, Johannes, Papsdorf, Gisela, Bienert, Michael

“…The influence of the peptide-to-cell ratio and energy depletion on uptake and degradation of the cell-penetrating peptides (CPPs) MAP (model amphipathic…”
Get full text

Structural Requirements for Cellular Uptake and Antisense Activity of Peptide Nucleic Acids Conjugated with Various Peptides by Wolf, Yvonne, Pritz, Stephan, Abes, Saïd, Bienert, Michael, Lebleu, Bernard, Oehlke, Johannes

“…Peptide nucleic acids (PNAs) have shown great promise as potential antisense drugs; however, poor cellular delivery limits their applications. Improved…”
Get full text

Cellular uptake of an α-helical amphipathic model peptide with the potential to deliver polar compounds into the cell interior non-endocytically by Oehlke, Johannes, Scheller, Anne, Wiesner, Burkhard, Krause, Eberhard, Beyermann, Michael, Klauschenz, Erhard, Melzig, Mathias, Bienert, Michael

“…Evidence that multiple, probably non-endocytic mechanisms are involved in the uptake into mammalian cells of the α-helical amphipathic model peptide…”
Get full text

Disposition of the 3H-labeled gonadotropin-releasing hormone analog buserelin in rats by Berger, H, Sandow, J, Heinrich, N, Albrecht, E, Kertscher, U, Oehlke, J

“…The short-time disposition of 3H-labeled D-Ser(TBU)6-desGly10-GnRH-ethylamide ([3H]buserelin) was studied in rats after bolus intravenous and subcutaneous…”
Get more information

Actin remodeling requires ERM function to facilitate AQP2 apical targeting by Tamma, Grazia, Klussmann, Enno, Oehlke, Johannes, Krause, Eberhard, Rosenthal, Walter, Svelto, Maria, Valenti, Giovanna

“…This study provides the first evidence that actin reorganization during AQP2 vesicular trafficking to the plasma membrane requires the functional involvement…”
Get full text

Cellular uptake and biological activity of peptide nucleic acids conjugated with peptides with and without cell-penetrating ability by Turner, Yvonne, Wallukat, Gerd, Säälik, Pille, Wiesner, Burkhard, Pritz, Stephan, Oehlke, Johannes

“…A 12‐mer peptide nucleic acid (PNA) directed against the nociceptin/orphanin FQ receptor mRNA was disulfide bridged with various peptides without and with…”
Get full text

Growth factor- and adhesion protein-like components of fetal calf serum can significantly enhance the intracellular delivery of Peptide nucleic acids by Oehlke, Johannes, Ehrlich, Angelika, Krause, Eberhard, Pritz, Stephan, Wiesner, Burkhard, Beyermann, Michael

“…Evidence is presented that components of fetal calf serum (FCS) can significantly enhance the splicing correction activity of peptide nucleic acids (PNA) in…”
Get more information

Studies on the cellular uptake of substance P and lysine-rich, KLA-derived model peptides by Oehlke, Johannes, Lorenz, Dorothea, Wiesner, Burkhard, Bienert, Michael

“…In the last decade many peptides have been shown to be internalized into various cell types by different, poorly characterized mechanisms. This review focuses…”
Get full text

Impact of a Drop-in Group Medical Appointment on Tobacco Quit Rates by Harris, Jessica L, Danley, Steffanie M, Jansen, Tarryn, Oehlke, Kelley J

“…The tobacco quit rate of veterans on pharmacotherapy who attended at least 1 drop-in group session was higher than the quit rate of veterans only on…”
Get full text

Structural requirements for cellular uptake of α-helical amphipathic peptides by Scheller, Anne, Oehlke, Johannes, Wiesner, Burkhard, Dathe, Margitta, Krause, Eberhard, Beyermann, Michael, Melzig, Mathias, Bienert, Michael

“…The structure of the cell‐permeable α‐helical amphipathic model peptide FLUOS‐KLALKLALKALKAALKLA‐NH2 (I) was modified stepwise with respect to its helix…”
Get full text

Extensive cellular uptake into endothelial cells of an amphipathic β-sheet forming peptide by Oehlke, Johannes, Krause, Eberhard, Wiesner, Burkhard, Beyermann, Michael, Bienert, Michael

“…Extensive internalization into endothelial cells has been found for a water soluble amphipathic 26-mer β-sheet peptide (FLUOS-DPKGDPKGVTVTVTVTVTGKGDPKPD-NH2;…”
Get full text

Smoking cessation update by Oehlke, Kelley J

Get more information

Enhancement of intracellular concentration and biological activity of PNA after conjugation with a cell‐penetrating synthetic model peptide by Oehlke, Johannes, Wallukat, Gerd, Wolf, Yvonne, Ehrlich, Angelika, Wiesner, Burkhard, Berger, Hartmut, Bienert, Michael

“…In order to evaluate the ability of the cell‐penetrating α‐helical amphipathic model peptide KLALKLALKALKAALKLA‐NH2 (MAP) to deliver peptide nucleic acids…”
Get full text

Benign prostatic hyperplasia--review of treatment options by Oehlke, Kelley J, Branaugh, Molly L

Get more information

Evidence for an amphipathicity independent cellular uptake of amphipathic cell‐penetrating peptides by Scheller, Anne, Wiesner, Burkhard, Melzig, Matthias, Bienert, Michael, Oehlke, Johannes

“…The cellular uptake of a peptide set derived from membrane‐permeable α‐helical amphipathic peptides by stepwise alterations of structure forming propensity and…”
Get full text

Evidence for extensive and non-specific translocation of oligopeptides across plasma membranes of mammalian cells by Oehlke, Johannes, Beyermann, Michael, Wiesner, Burkhard, Melzig, Mathias, Berger, Hartmut, Krause, Eberhard, Bienert, Michael

“…After exposure of bovine aortic endothelial cells to various small peptides (tetra- to undeca-mer), extensive transport of the peptides across the plasma…”
Get full text

P 10 Evidence for an unspecific and extensive transport of small peptides into and across aortic and brain microvessel endothelial cells by Oehlke, J., Beyermann, M., Krause, E., Bienert, M.

Get full text

Interactions between desoxycholic acid glucuronides and glucuronidase (author's transl) by Oehlke, J

“…It has been found that desoxycholic acid-3- (1), -12- (2) and -3,12-bis-beta-D-glucuronide (3) exert a potent allosteric effect on the beta-glucuronidase…”
Get more information