Search Results - "Oeckler, Richard A."

Etiology, incidence, and outcomes of patient–ventilator asynchrony in critically-ill patients undergoing invasive mechanical ventilation by Zhou, Yongfang, Holets, Steven R., Li, Man, Cortes-Puentes, Gustavo A., Meyer, Todd J., Hanson, Andrew C., Schulte, Phillip J., Oeckler, Richard A.

“…Patient–ventilator asynchrony (PVA) is commonly encountered during mechanical ventilation of critically ill patients. Estimates of PVA incidence vary widely…”
Get full text

Risk Factors for Dexmedetomidine-Associated Hemodynamic Instability in Noncardiac Intensive Care Unit Patients by Ice, Calvin J., Personett, Heather A., Frazee, Erin N., Dierkhising, Ross A., Kashyap, Rahul, Oeckler, Richard A.

“…The reported incidence of hypotension and bradycardia in patients receiving dexmedetomidine for sedation commonly exceeds 50%. In this study, we describe the…”
Get full text

TRIM72 modulates caveolar endocytosis in repair of lung cells by Nagre, Nagaraja, Wang, Shaohua, Kellett, Thomas, Kanagasabai, Ragu, Deng, Jing, Nishi, Miyuki, Shilo, Konstantin, Oeckler, Richard A, Yalowich, Jack C, Takeshima, Hiroshi, Christman, John, Hubmayr, Rolf D, Zhao, Xiaoli

“…Alveolar epithelial and endothelial cell injury is a major feature of the acute respiratory distress syndrome, in particular when in conjunction with…”
Get more information

Sizing the lung of mechanically ventilated patients by Mattingley, Jennifer S, Holets, Steven R, Oeckler, Richard A, Stroetz, Randolph W, Buck, Curtis F, Hubmayr, Rolf D

“…This small observational study was motivated by our belief that scaling the tidal volume in mechanically ventilated patients to the size of the injured lung is…”
Get full text

Stretch Enhances Contraction of Bovine Coronary Arteries via an NAD(P)H Oxidase–Mediated Activation of the Extracellular Signal–Regulated Kinase Mitogen-Activated Protein Kinase Cascade by Oeckler, Richard A, Kaminski, Pawel M, Wolin, Michael S

“…ABSTRACT—This study examines the effects of an increase in passive stretch in endothelium-removed bovine coronary artery on oxidant-induced changes in force…”
Get full text

Determinants of plasma membrane wounding by deforming stress by Oeckler, Richard A, Lee, Won-Yeon, Park, Mun-Gi, Kofler, Othmar, Rasmussen, Deborah L, Lee, Heung-Bum, Belete, Hewan, Walters, Bruce J, Stroetz, Randolph W, Hubmayr, Rolf D

“…Once excess liquid gains access to air spaces of an injured lung, the act of breathing creates and destroys foam and thereby contributes to the wounding of…”
Get more information

Positional effects on the distributions of ventilation and end-expiratory gas volume in the asymmetric chest—a quantitative lung computed tomographic analysis by Cortes-Puentes, Gustavo A., Gard, Kenneth E., Adams, Alexander B., Dries, David J., Quintel, Michael, Oeckler, Richard A., Gattinoni, Luciano, Marini, John J.

“…Background Body positioning affects the configuration and dynamic properties of the chest wall and therefore may influence decisions made to increase or…”
Get full text

Understanding Ventilator Operation: Importance of the Respiratory Therapist at the Bedside by LeTourneau, William M, Oeckler, Richard A

Get full text

Ketamine/propofol admixture vs etomidate for intubation in the critically ill: KEEP PACE Randomized clinical trial by Smischney, Nathan Jerome, Nicholson, Wayne T, Brown, Daniel R, Gallo De Moraes, Alice, Hoskote, Sumedh S, Pickering, Brian, Oeckler, Richard A, Iyer, Vivek N, Gajic, Ognjen, Schroeder, Darrell R, Bauer, Philippe R

“…Periintubation hypotension is associated with poor outcomes in the critically ill. We aimed to determine if an admixture of ketamine and propofol for emergent…”
Get full text

Early Neuromuscular Blockade in the Acute Respiratory Distress Syndrome by Gallo de Moraes, Alice, El-Yafawi, Rama, Oeckler, Richard A

Get full text

Superoxide in the vascular system by Wolin, Michael S, Gupte, Sachin A, Oeckler, Richard A

“…Oxidant production and regulation is becoming increasingly important in the study of vascular signaling mechanisms, and recent reviews have characterized some…”
Get more information

Thiol oxidation inhibits nitric oxide-mediated pulmonary artery relaxation and guanylate cyclase stimulation by Mingone, Christopher J, Gupte, Sachin A, Ali, Noorjahan, Oeckler, Richard A, Wolin, Michael S

“…The mechanisms through which thiol oxidation and cellular redox influence the regulation of soluble guanylate cyclase (sGC) are poorly understood. This study…”
Get more information

Creating Successful Emergency Department and Intensive Care Unit Team Dynamics by Clements, Casey M., Oeckler, Richard A., Heaton, Heather A., Diedrich, Daniel A., Brown, Daniel R., Sampathkumar, Priya

Get full text

Hypercapnia Alters Alveolar Epithelial Repair by a pH-Dependent and Adenylate Cyclase-Mediated Mechanism by Cortes-Puentes, Gustavo A., Westerly, Blair, Schiavo, Dante, Wang, Shaohua, Stroetz, Randolph, Walters, Bruce, Hubmayr, Rolf D., Oeckler, Richard A.

“…Lung cell injury and repair is a hallmark of the acute respiratory distress syndrome (ARDS). Lung protective mechanical ventilation strategies in these…”
Get full text

High-Flow Nasal Cannula on the General Ward for Patients With COVID-19 Enhances ICU and Rapid Response Team Resource Allocation by Zhong, Qiaonan, Chaudhary, Connie W, Stellpflug, Courtney L, Wolf, Christine S, Diedrich, Daniel A, Lehnertz, Andrea, Meyer, Todd J, Oeckler, Richard A, De Moraes, Alice Gallo

Get full text

Refractory Hypoxemia and Use of Rescue Strategies. A U.S. National Survey of Adult Intensivists by Alhurani, Rabe E, Oeckler, Richard A, Franco, Pablo Moreno, Jenkins, Sarah M, Gajic, Ognjen, Pannu, Sonal R

“…The management of severe and refractory hypoxemia in critically ill adult patients is practice based. Variability across individual practitioners and…”
Get full text

Evaluation of Suspected Aspirated Beverage Can Pull Tab: Radiographs May Not Be Enough by Kuzo, Ronald S., Oeckler, Richard A., Campeau, Norbert G., Kotsenas, Amy L.

“…A 67-year-old male presented to the emergency department with concern for accidental aspiration of an aluminum beverage can pull tab. Neck and chest…”
Get full text

The Impact of a Standardized Refractory Hypoxemia Protocol on Outcome of Subjects Receiving Venovenous Extracorporeal Membrane Oxygenation by Zhou, Yongfang, Holets, Steven R, Li, Man, Meyer, Todd J, Rangel Latuche, Laureano J, Oeckler, Richard A, Bohman, John K

“…Current mechanical ventilation practice and the use of treatment adjuncts in patients requiring extracorporeal membrane oxygenation (ECMO) for refractory…”
Get full text

Integration of Pulmonary Mechanics in a Personalized Approach to Mechanical Ventilation by Cortes-Puentes, Gustavo A, Holets, Steven R, Oeckler, Richard A

Get full text

Physiology-guided management of hemodynamics in acute respiratory distress syndrome by Cortes-Puentes, Gustavo A, Oeckler, Richard A, Marini, John J

“…Skillfully implemented mechanical ventilation (MV) may prove of immense benefit in restoring physiologic homeostasis. However, since hemodynamic instability is…”
Get full text