Alcoholic Acute Pancreatitis, a Retrospective Study about Clinical Risk Factors and Outcomes-A Seven-Year Experience of a Large Tertiary Center

Alcoholic Acute Pancreatitis, a Retrospective Study about Clinical Risk Factors and Outcomes-A Seven-Year Experience of a Large Tertiary Center

(1) Background: Alcohol consumption is one of the main causes of acute pancreatitis. (2) Material and Methods: In this unicentric retrospective cohort study, we selected 1855 patients from the Bucharest Acute Pancreatitis Index (BUC-API) who presented with acute pancreatitis. We investigated correla...

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Published in:Biomedicines Vol. 12; no. 6; p. 1299
Main Authors: Gűnșahin, Deniz, Edu, Andrei Vicențiu, Pahomeanu, Mihai Radu, Mitu, Tudor Ștefan, Ghiță, Andreea Irina, Odorog, Anamaria Simona, Preda, Carmen Monica, Negreanu, Lucian
Format: Journal Article
Language:English
Published: Switzerland MDPI AG 01-06-2024
MDPI
Subjects:
acute pancreatitis
Alcohol
Chi-square test
Disease prevention
Electronic health records
Etiology
Health aspects
Hospitalization
Hospitals
ICU
Israel
Medical research
Medicine, Experimental
Morphology
Mortality
outcome
Pancreatitis
Patients
Population
recurrence
Risk factors
Romania
Smoking
Statistical analysis
Tobacco
Romania
Israel
Atlanta Georgia
Bucharest Romania
United States > US
alcohol
recurrence
risk factors
cost
acute pancreatitis
ICU
pseudocyst
outcome
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Summary:(1) Background: Alcohol consumption is one of the main causes of acute pancreatitis. (2) Material and Methods: In this unicentric retrospective cohort study, we selected 1855 patients from the Bucharest Acute Pancreatitis Index (BUC-API) who presented with acute pancreatitis. We investigated correlations between Alcoholic Acute Pancreatitis (AAP) and the rate of complications, cost, length of hospitalization and rate of recurrence. (3) Results: We found a moderately strong association between AAP and recurrence ( < 0.01) and observed that the disease is likelier to evolve with pseudocysts and walled-off necrosis than other forms of AP. Patients with AAP are less likely to have a morphologically normal pancreas than patients suffering from AP of other causes ( < 0.01), but a low probability of requiring intensive care unit admission ( < 0.01) significantly lowers daily cost (Md = 154.7 EUR compared to Md = 204.4 EUR) ( < 0.01). (4) Conclusions: This study's data show that patients with AAP have a greater rate of pseudocyst occurrence, lower intensive care unit admittance rate and lower cost of hospitalization than patients with AP of other causes. Typical Sketch: A middle-aged male tobacco smoker with recurrent AP, lower risk of in-hospital mortality and complications such as pseudocysts; treated in a gastroenterological ward and discharged at-will.
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ISSN:2227-9059
2227-9059
DOI:10.3390/biomedicines12061299