Search Results - "Odonnell, R."

Genomic and functional analyses of Mycobacterium tuberculosis strains implicate ald in D-cycloserine resistance by Desjardins, Christopher A, Cohen, Keira A, Munsamy, Vanisha, Abeel, Thomas, Maharaj, Kashmeel, Walker, Bruce J, Shea, Terrance P, Almeida, Deepak V, Manson, Abigail L, Salazar, Alex, Padayatchi, Nesri, O'Donnell, Max R, Mlisana, Koleka P, Wortman, Jennifer, Birren, Bruce W, Grosset, Jacques, Earl, Ashlee M, Pym, Alexander S

“…Alexander Pym, Ashlee Earl and colleagues use the whole-genome sequences from 498 strains of Mycobacterium tuberculosis to identify new genotypes conferring…”
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Heat treatment of high-pressure die castings by LUMLEY, R. N, ODONNELL, R. G, GUNASEGARAM, D. R, GIVORD, M

“…High-pressure die-cast Al alloys cannot normally be heated at high temperatures due to the presence of pores containing entrapped gases, which lead to the…”
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Cultural-Historical Activity Theory and Cultural Community Psychology: The Potential for Greater Commonality by Tharp, Roland G., O'Donnell, Clifford R.

“…Greater commonality for Cultural-Community Psychology (CC) and cultural-historical activity theory (CHAT) is advocated. The potential for greater commonality…”
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A scoping review of academic and grey literature on migrant health research conducted in Scotland by Petrie, G, Angus, K, O'Donnell, R

“…Migration to Scotland has increased since 2002 with an increase in European residents and participation in the Asylum dispersal scheme. Scotland has become…”
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Systematic review of clofazimine for the treatment of drug-resistant tuberculosis [Review article] by Gopal, M., Padayatchi, N., Metcalfe, J. Z., O'Donnell, M. R.

“…The increased incidence of drug-resistant tuberculosis has created an urgent necessity for the development of new and effective anti-tuberculosis drugs and for…”
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Mechanical Ventilation Guided by Esophageal Pressure in Acute Lung Injury by Talmor, Daniel, Sarge, Todd, Malhotra, Atul, O'Donnell, Carl R, Ritz, Ray, Lisbon, Alan, Novack, Victor, Loring, Stephen H

“…Positive end-expiratory pressure (PEEP) is used to improve oxygenation in patients with acute lung injury or the acute respiratory distress syndrome. In this…”
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Colloidal Aggregators in Biochemical SARS-CoV‑2 Repurposing Screens by O’Donnell, Henry R, Tummino, Tia A, Bardine, Conner, Craik, Charles S, Shoichet, Brian K

“…To fight COVID-19, much effort has been directed toward in vitro drug repurposing. Here, we investigate the impact of colloidal aggregation, a common screening…”
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Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2 by Tummino, Tia A, Rezelj, Veronica V, Fischer, Benoit, Fischer, Audrey, O'Meara, Matthew J, Monel, Blandine, Vallet, Thomas, White, Kris M, Zhang, Ziyang, Alon, Assaf, Schadt, Heiko, O'Donnell, Henry R, Lyu, Jiankun, Rosales, Romel, McGovern, Briana L, Rathnasinghe, Raveen, Jangra, Sonia, Schotsaert, Michael, Galarneau, Jean-René, Krogan, Nevan J, Urban, Laszlo, Shokat, Kevan M, Kruse, Andrew C, García-Sastre, Adolfo, Schwartz, Olivier, Moretti, Francesca, Vignuzzi, Marco, Pognan, Francois, Shoichet, Brian K

“…Repurposing drugs as treatments for COVID-19, the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has drawn much attention…”
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Racial and ethnic disparities post-hospitalization for COVID-19: barriers to access to care for survivors of COVID-19 acute respiratory distress syndrome by Cañas, Alicia, Wolf, Allison, Mak, Angela, Ruddy, Jacob, El-Sadek, Sal, Gomez, Laura, Furfaro, David, Fullilove, Robert, Burkart, Kristin M., Zelnick, Jennifer, O’Donnell, Max R.

“…Racial and ethnic health disparities in the incidence and severity of Coronavirus Disease 2019 (COVID-19) have been observed globally and in the United States…”
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Total Synthesis of (−)-Aspidospermidine via an Enantioselective Palladium-Catalyzed Allylic Substitution Strategy by O’Donnell, Charlotte R., Stark, Christian B. W.

“…A total synthesis of (−)-aspidospermidine via an enantioselective Pd-catalyzed allylic substitution strategy is reported. This represents the first application…”
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Latent Class Analysis Reveals COVID-19-related Acute Respiratory Distress Syndrome Subgroups with Differential Responses to Corticosteroids by Sinha, Pratik, Furfaro, David, Cummings, Matthew J, Abrams, Darryl, Delucchi, Kevin, Maddali, Manoj V, He, June, Thompson, Alison, Murn, Michael, Fountain, John, Rosen, Amanda, Robbins-Juarez, Shelief Y, Adan, Matthew A, Satish, Tejus, Madhavan, Mahesh, Gupta, Aakriti, Lyashchenko, Alexander K, Agerstrand, Cara, Yip, Natalie H, Burkart, Kristin M, Beitler, Jeremy R, Baldwin, Matthew R, Calfee, Carolyn S, Brodie, Daniel, O'Donnell, Max R

“…Two distinct subphenotypes have been identified in acute respiratory distress syndrome (ARDS), but the presence of subgroups in ARDS associated with…”
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A genetic screen for improved plasmid segregation reveals a role for Rep20 in the interaction of Plasmodium falciparum chromosomes by O'Donnell, Rebecca A., Freitas-Junior, Lúcio H., Preiser, Peter R., Williamson, Donald H., Duraisingh, Manoj, McElwain, Terry F., Scherf, Artur, Cowman, Alan F., Crabb, Brendan S.

“…Bacterial plasmids introduced into the human malaria parasite Plasmodium falciparum replicate well but are poorly segregated during mitosis. In this paper, we…”
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Multicenter, Phase II Study of Decitabine for the First-Line Treatment of Older Patients With Acute Myeloid Leukemia by CASHEN, Amanda F, SCHILLER, Gary J, O'DONNELL, Margaret R, DIPERSIO, John F

“…Older patients with acute myeloid leukemia (AML) have limited treatment options because of the lack of effectiveness and the toxicity of available therapies…”
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Multidimensional Dyspnea Profile: an instrument for clinical and laboratory research by Banzett, Robert B, O'Donnell, Carl R, Guilfoyle, Tegan E, Parshall, Mark B, Schwartzstein, Richard M, Meek, Paula M, Gracely, Richard H, Lansing, Robert W

“…There is growing awareness that dyspnoea, like pain, is a multidimensional experience, but measurement instruments have not kept pace. The Multidimensional…”
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Inflammatory cells in the airways in COPD by O’Donnell, R, Breen, D, Wilson, S, Djukanovic, R

“…Airway inflammation is central to the pathogenesis of both airway remodelling and parenchymal destruction in chronic obstructive pulmonary disease (COPD)…”
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Rapid thermal adaptation in a marine diatom reveals constraints and trade‐offs by O'Donnell, Daniel R., Hamman, Carolyn R., Johnson, Evan C., Kremer, Colin T., Klausmeier, Christopher A., Litchman, Elena

“…Rapid evolution in response to environmental change will likely be a driving force determining the distribution of species across the biosphere in coming…”
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Relationship between peripheral airway dysfunction, airway obstruction, and neutrophilic inflammation in COPD by O’Donnell, R A, Peebles, C, Ward, J A, Daraker, A, Angco, G, Broberg, P, Pierrou, S, Lund, J, Holgate, S T, Davies, D E, Delany, D J, Wilson, S J, Djukanovic, R

“…Background: Considerable research has been conducted into the nature of airway inflammation in chronic obstructive pulmonary disease (COPD) but the…”
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Evaluation of screening strategies for pulmonary tuberculosis among hospitalized patients in a low-burden setting: cost-effectiveness of GeneXpert MTB/RIF compared to smear microscopy by Hickey, Andrew J., Cummings, Matthew J., Zafari, Zafar, Louh, Irene K., Li, Jianhua, O’Donnell, Max R.

“…Objective:Hospitalized patients undergoing evaluation for pulmonary tuberculosis (TB) require airborne isolation while testing for Mycobacterium tuberculosis…”
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COVID-19 immune signatures in Uganda persist in HIV co-infection and diverge by pandemic phase by Cummings, Matthew J., Bakamutumaho, Barnabas, Lutwama, Julius J., Owor, Nicholas, Che, Xiaoyu, Astorkia, Maider, Postler, Thomas S., Kayiwa, John, Kiconco, Jocelyn, Muwanga, Moses, Nsereko, Christopher, Rwamutwe, Emmanuel, Nayiga, Irene, Kyebambe, Stephen, Haumba, Mercy, Bosa, Henry Kyobe, Ocom, Felix, Watyaba, Benjamin, Kikaire, Bernard, Tomoiaga, Alin S., Kisaka, Stevens, Kiwanuka, Noah, Lipkin, W. Ian, O’Donnell, Max R.

“…Little is known about the pathobiology of SARS-CoV-2 infection in sub-Saharan Africa, where severe COVID-19 fatality rates are among the highest in the world…”
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Adherence Measured Using Electronic Dose Monitoring is Associated with Emergent Antiretroviral Resistance and Poor Outcomes in People with Human Immunodeficiency Virus/AIDS and Multidrug-Resistant Tuberculosis by Bateman, Mark, Wolf, Allison, Chimukangara, Benjamin, Brust, James C M, Lessells, Richard, Amico, Rivet, Boodhram, Resha, Singh, Nalini, Orrell, Catherine, Friedland, Gerald, Naidoo, Kogieleum, Padayatchi, Nesri, O'Donnell, Max R

“…Medication adherence is known to challenge treatment of human immunodeficiency virus (HIV)/AIDS and multidrug-resistant tuberculosis (MDR-TB). We hypothesized…”
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