Search Results - "Odiba, Arome Solomon"

Gene therapy in PIDs, hemoglobin, ocular, neurodegenerative, and hemophilia B disorders by Odiba, Arome Solomon, Okoro, Nkwachukwu Oziamara, Durojaye, Olanrewaju Ayodeji, Wu, Yanjun

“…A new approach is adopted to treat primary immunodeficiency disorders, such as the severe combined immunodeficiency (SCID; e.g., adenosine deaminase SCID…”
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Disparate roles for C. elegans DNA translocase paralogs RAD-54.L and RAD-54.B in meiotic prophase germ cells by Yamaya, Kei, Wang, Bin, Memar, Nadin, Odiba, Arome Solomon, Woglar, Alexander, Gartner, Anton, Villeneuve, Anne M

“…RAD54 family DNA translocases partner with RAD51 recombinases to ensure stable genome inheritance, exhibiting biochemical activities both in promoting…”
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MasitinibL shows promise as a drug-like analog of masitinib that elicits comparable SARS-Cov-2 3CLpro inhibition with low kinase preference by Durojaye, Olanrewaju Ayodeji, Okoro, Nkwachukwu Oziamara, Odiba, Arome Solomon, Nwanguma, Bennett Chima

“…SARS-CoV-2 infection has led to several million deaths worldwide and ravaged the economies of many countries. Hence, developing therapeutics against SARS-CoV-2…”
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Caenorhabditis elegans NSE3 homolog (MAGE-1) is involved in genome stability and acts in inter-sister recombination during meiosis by Odiba, Arome Solomon, Liao, Guiyan, Ezechukwu, Chiemekam Samuel, Zhang, Lanlan, Hong, Ye, Fang, Wenxia, Jin, Cheng, Gartner, Anton, Wang, Bin

“…Abstract Melanoma antigen (MAGE) genes encode for a family of proteins that share a common MAGE homology domain. These genes are conserved in eukaryotes and…”
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Bioactive Phytochemicals with Anti-Aging and Lifespan Extending Potentials in Caenorhabditis elegans by Okoro, Nkwachukwu Oziamara, Odiba, Arome Solomon, Osadebe, Patience Ogoamaka, Omeje, Edwin Ogechukwu, Liao, Guiyan, Fang, Wenxia, Jin, Cheng, Wang, Bin

“…In the forms of either herbs or functional foods, plants and their products have attracted medicinal, culinary, and nutraceutical applications due to their…”
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Isolation, Identification and Molecular Mechanism Analysis of the Nematicidal Compound Spectinabilin from Newly Isolated Streptomyces sp. DT10 by Sun, Yuchen, Xie, Jin, Tang, Lihua, Odiba, Arome Solomon, Chen, Yanlu, Fang, Wenxia, Wu, Xiaogang, Wang, Bin

“…Plant parasitic nematodes (PPNs) are highly destructive and difficult to control, while conventional chemical nematicides are highly toxic and cause serious…”
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Polysaccharides Extracted from Dendrobium officinale Grown in Different Environments Elicit Varying Health Benefits in Caenorhabditis elegans by Okoro, Nkwachukwu Oziamara, Odiba, Arome Solomon, Yu, Qi, He, Bin, Liao, Guiyan, Jin, Cheng, Fang, Wenxia, Wang, Bin

“…is one of the most widely used medicinal herbs, especially in Asia. In recent times, the polysaccharide content of has garnered attention due to the numerous…”
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Ganoderma lucidum methyl ganoderate E extends lifespan and modulates aging-related indicators in Caenorhabditis elegans by Okoro, Nkwachukwu Oziamara, Odiba, Arome Solomon, Han, Junjie, Osadebe, Patience Ogoamaka, Omeje, Edwin Ogechukwu, Liao, Guiyan, Liu, Yichen, Jin, Cheng, Fang, Wenxia, Liu, Hongwei, Wang, Bin

“…Methyl Ganoderate E (MGE) is a triterpenoid derived from (Reishi), an edible mushroom, commonly processed into food forms such as soups, drinks, culinary…”
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Loss of NSE-4 Perturbs Genome Stability and DNA Repair in Caenorhabditis elegans by Odiba, Arome Solomon, Ezechukwu, Chiemekam Samuel, Liao, Guiyan, Li, Siqiao, Chen, Zhongliang, Liu, Xihui, Fang, Wenxia, Jin, Cheng, Wang, Bin

“…The Structural Maintenance of Chromosomes (SMC) complex plays an important role in maintaining chromosome integrity, in which the SMC5/6 complex occupies a…”
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Phosphoglucose Isomerase Plays a Key Role in Sugar Homeostasis, Stress Response, and Pathogenicity in Aspergillus flavus by Zhou, Yao, Du, Chao, Odiba, Arome Solomon, He, Rui, Ahamefule, Chukwuemeka Samson, Wang, Bin, Jin, Cheng, Fang, Wenxia

“…is one of the important human and plant pathogens causing not only invasive aspergillosis in immunocompromised patients but also crop contamination resulting…”
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Comparatively analyzing the liver-specific transcriptomic profiles in Kunming mice afflicted with streptozotocin- and natural food-induced type 2 diabetes mellitus by Wu, Yanjun, Zhu, Xiangxing, Odiba, Arome Solomon, Lin, Zisheng, Wen, Jiancong, Gong, Daoyuan, Liang, Jing, Wu, Shuguang, Lan, Ganqiu

“…Background Streptozotocin is a classic drug used to induce diabetes in animal models. Objective The aim of this study is to investigate the liver transcriptome…”
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Modulation of immunological responses by aqueous extract of Datura stramonium L. seeds on cyclophosphamide-induced immunosuppression in Wistar rats by Joshua, Parker Elijah, Yahaya, Junaidu, Ekpo, Daniel Emmanuel, Ogidigo, Joyce Oloaigbe, Odiba, Arome Solomon, Asomadu, Rita Onyekachukwu, Oka, Samson Ayodeji, Adeniyi, Olasupo Stephen

“…Datura stramonium L. (Solanaceae) is used traditionally in west Africa to treat asthma, epilepsy, rheumatoid arthritis, filariasis microbial infections and…”
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New advances in protein engineering for industrial applications: Key takeaways by Ndochinwa, Giles Obinna, Wang, Qing-Yan, Okoro, Nkwachukwu Oziamara, Amadi, Oyetugo Chioma, Nwagu, Tochukwu Nwamaka, Nnamchi, Chukwudi Innocent, Moneke, Anene Nwabu, Odiba, Arome Solomon

“…Recent advancements in protein/enzyme engineering have enabled the production of a diverse array of high-value compounds in microbial systems with the…”
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Phosphomannose Isomerase Is Involved in Development, Stress Responses, and Pathogenicity of Aspergillus flavus by Usman, Sayed, Du, Chao, Qin, Qijian, Odiba, Arome Solomon, He, Rui, Wang, Bin, Jin, Cheng, Fang, Wenxia

“…Aspergillus flavus causes invasive aspergillosis in immunocompromised patients and severe contamination of agriculturally important crops by producing…”
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FTO gene expression in diet-induced obesity is downregulated by Solanum fruit supplementation by Asuquo, Edeke Affiong, Nwodo, Okwesilieze Fred Chiletugo, Assumpta, Anosike Chioma, Orizu, Uchendu Nene, Oziamara, Okoro Nkwachukwu, Solomon, Odiba Arome

“…The Fat Mass and Obesity-associated (FTO) gene has been shown to play an important role in developing obesity, manifesting in traits such as increased body…”
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Characterization of the SARS-CoV-2 coronavirus X4-like accessory protein by Durojaye, Olanrewaju Ayodeji, Okoro, Nkwachukwu Oziamara, Odiba, Arome Solomon

“…Background The novel coronavirus SARS-CoV-2 is currently a global threat to health and economies. Therapeutics and vaccines are in rapid development; however,…”
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Caenorhabditis elegans- Based Aspergillus fumigatus Infection Model for Evaluating Pathogenicity and Drug Efficacy by Ahamefule, Chukwuemeka Samson, Qin, Qijian, Odiba, Arome Solomon, Li, Siqiao, Moneke, Anene N, Ogbonna, James C, Jin, Cheng, Wang, Bin, Fang, Wenxia

“…is the most reported causative pathogen associated with the increasing global incidences of aspergilloses, with the health of immunocompromised individuals…”
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Investigation of the MDM2-binding potential of de novo designed peptides using enhanced sampling simulations by Durojaye, Olanrewaju Ayodeji, Yekeen, Abeeb Abiodun, Idris, Mukhtar Oluwaseun, Okoro, Nkwachukwu Oziamara, Odiba, Arome Solomon, Nwanguma, Bennett Chima

“…The tumor suppressor p53 plays a crucial role in cellular responses to various stresses, regulating key processes such as apoptosis, senescence, and DNA…”
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Aldehyde dehydrogenase plays crucial roles in response to lower temperature stress in Solanum tuberosum and Nicotiana benthamiana by Guo, Jiangbo, Sun, Wei, Liu, Hanyang, Chi, Junling, Odiba, Arome Solomon, Li, Guangcun, Jin, Liping, Xin, Cuihua

“…•Intragenic DNA methylation of StALDH2B7a is modulated by cold stress in potato.•StALDH2B7a expression is correlated to intragenic DNA methylation…”
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SMC-5/6 complex subunit NSE-1 plays a crucial role in meiosis and DNA repair in Caenorhabditis elegans by Odiba, Arome Solomon, Ezechukwu, Chiemekam Samuel, Liao, Guiyan, Hong, Ye, Fang, Wenxia, Jin, Cheng, Gartner, Anton, Wang, Bin

“…The SMC5/6 complex is evolutionarily conserved across all eukaryotes and plays a pivotal role in preserving genomic stability. Mutations in genes encoding…”
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