Search Results - "Odero, M D"

PP2A impaired activity is a common event in acute myeloid leukemia and its activation by forskolin has a potent anti-leukemic effect by Cristóbal, I, Garcia-Orti, L, Cirauqui, C, Alonso, M M, Calasanz, M J, Odero, M D

“…Protein phosphatase 2A (PP2A) is a human tumor suppressor that inhibits cellular transformation by regulating the activity of several signaling proteins…”
Get full text

Effect of FTY720 on the SET–PP2A complex in acute myeloid leukemia; SET binding drugs have antagonistic activity by Pippa, R, Dominguez, A, Christensen, D J, Moreno-Miralles, I, Blanco-Prieto, M J, Vitek, M P, Odero, M D

Get full text

Epigenetic regulation of miRNA genes in acute leukemia by Agirre, X, Martínez-Climent, J Á, Odero, M D, Prósper, F

“…MicroRNAs (miRNAs) are small non-coding RNA molecules that can negatively regulate gene expression at the post-transcriptional level. miRNA expression patterns…”
Get full text

Functional characterization of the promoter region of the human EVI1 gene in acute myeloid leukemia: RUNX1 and ELK1 directly regulate its transcription by Maicas, M, Vázquez, I, Vicente, C, García-Sánchez, M A, Marcotegui, N, Urquiza, L, Calasanz, M J, Odero, M D

“…The EVI1 gene (3q26) codes for a transcription factor with important roles in normal hematopoiesis and leukemogenesis. High expression of EVI1 is a negative…”
Get full text

In vivo expression of an aberrant MYB-GATA1 fusion induces leukemia in the presence of GATA1 reduced levels by Belloni, E, Shing, D, Tapinassi, C, Viale, A, Mancuso, P, Malazzi, O, Gerbino, E, Dall'Olio, V, Egurbide, I, Odero, M D, Bertolini, F, Giuseppe Pelicci, P

Get full text

Lipid Nanosystems Enhance the Bioavailability and the Therapeutic Efficacy of FTY720 in Acute Myeloid Leukemia by Estella-Hermoso de Mendoza, A, Castello-Cros, R, Imbuluzqueta, E, Cirauqui, C, Pippa, R, Odero, M D, Blanco-Prieto, M J

“…Protein phosphatase 2A (PP2A) is a serin-threonin phosphatase that regulates many proteins critical for malignant cell behavior; therefore, PP2A is considered…”
Get more information

DNA profiling analysis of 100 consecutive de novo acute myeloid leukemia cases reveals patterns of genomic instability that affect all cytogenetic risk groups by SUELA, J, ALVAREZ, S, CALASANZ, M. J, CIGUDOSA, J. C, CIFUENTES, F, LARGO, C, FERREIRA, Bl, BLESA, D, ARDANAZ, M, GARCIA, R, MARQUEZ, J. A, ODERO, M. D

“…We have carried out a high-resolution whole genome DNA profiling analysis on 100 bone marrow samples from a consecutive series of de novo acute myeloid…”
Get full text

Disruption and aberrant expression of HMGA2 as a consequence of diverse chromosomal translocations in myeloid malignancies by Odero, M D, Grand, F H, Iqbal, S, Ross, F, Roman, J P, Vizmanos, J L, Andrieux, J, Laï, J L, Calasanz, M J, Cross, N C P

“…Chromosomal translocations that target HMGA2 at chromosome band 12q14 are seen in a variety of malignancies, notably lipoma, pleomorphic salivary adenoma and…”
Get full text

Abnormalities on 1q and 7q are associated with poor outcome in sporadic Burkitt's lymphoma. A cytogenetic and comparative genomic hybridization study by GARCIA, J. L, HERNANDEZ, J. M, ODERO, M. D, SAN MIGUEL, J. F, GUTIERREZ, N. C, FLORES, T, GONZALEZ, D, CALASANZ, M. J, MARTINEZ-CLIMENT, J. A, PIRIS, M. A, LOPEZ-CAPITAN, C, GONZALEZ, M. B

“…Comparative genomic hybridization (CGH) studies have demonstrated a high incidence of chromosomal imbalances in non-Hodgkin's lymphoma. However, the…”
Get full text

Genomic imbalances detected by comparative genomic hybridization are prognostic markers in invasive ductal breast carcinomas by Zudaire, I, Odero, M D, Caballero, C, Valenti, C, Martínez-Penuela, J M, Isola, J, Calasanz, M J

“…Genomic imbalances detected by comparative genomic hybridization are prognostic markers in invasive ductal breast carcinomas Aims: The aim of this work is the…”
Get full text

Overexpression of GATA2 predicts an adverse prognosis for patients with acute myeloid leukemia and it is associated with distinct molecular abnormalities by Vicente, C, Vazquez, I, Conchillo, A, García-Sánchez, M A, Marcotegui, N, Fuster, O, González, M, Calasanz, M J, Lahortiga, I, Odero, M D

Get full text

Characterization of Nonrandom Chromosomal Gains and Losses in Multiple Myeloma by Comparative Genomic Hybridization by Cigudosa, Juan C., Rao, Pulivarthi H., Calasanz, M. Jose, Odero, M. Dolores, Michaeli, Joseph, Jhanwar, Suresh C., Chaganti, R.S.K.

“…Clonal chromosomal changes in multiple myeloma (MM) and related disorders are not well defined, mainly due to the low in vivo and in vitro mitotic index of…”
Get full text

Further characterization of complex chromosomal rearrangements in myeloid malignancies: spectral karyotyping adds precision in defining abnormalities associated with poor prognosis by ODERO, M. D, CARLSON, K. M, CALASANZ, M. J, ROWLEY, I. D

Get full text

EVI1 controls proliferation in acute myeloid leukaemia through modulation of miR-1-2 by Gómez-Benito, M, Conchillo, A, García, M A, Vázquez, I, Maicas, M, Vicente, C, Cristobal, I, Marcotegui, N, García-Ortí, L, Bandrés, E, Calasanz, M J, Alonso, M M, Odero, M D

“…Bakground: The EVI1 (ecotropic virus integration site 1) gene codes for a zinc-finger transcription factor, whose transcriptional activation leads to a…”
Get full text

Cryptic ins(2;11) with clonal evolution showing amplification of 11q23-q25 either on hsr(11) or on dmin, in a patient with AML-M2 by Vazquez, I, Lahortiga, I, Agirre, X, Larrayoz, M J, Vizmanos, J L, Ardanaz, M T, Zeleznik-Le, N J, Calasanz, M J, Odero, M D

Get full text

JAK2-V617F activating mutation in acute myeloid leukemia: prognostic impact and association with other molecular markers by Vicente, C, Vázquez, I, Marcotegui, N, Conchillo, A, Carranza, C, Rivell, G, Bandrés, E, Cristobal, I, Lahortiga, I, Calasanz, M J, Odero, M D

Get full text

In vivo expression of an aberrant MYB-GATA1 fusion induces leukemia in the presence of GATA1 reduced levels by Belloni, E, Shing, D, Tapinassi, C, Viale, A, Mancuso, P, Malazzi, O, Gerbino, E, Dall'Olio, V, Egurbide, I, Odero, M.D, Bertolini, F, Pelicci, P.G

Get full text

Hypodiploidy and 22q11 rearrangements at diagnosis are associated with poor prognosis in patients with multiple myeloma by Calasanz, María J., Cigudosa, Juan C., Odero, MaríA D., García‐Foncillas, JesúS, Marín, Ulián, Ardanaz, Mariá T., Rocha, Eduardo, Gullón, Arturo

“…Our aim was to evaluate the clinical use of cytogenetic analysis as a prognostic factor in the outcome of newly diagnosed multiple myeloma (MM) patients. The…”
Get full text

Complex karyotype in one patient with small cell variant of T-prolymphocytic leukemia. Analysis by G-banding and comparative genomic hybridization by Odero, M D, Matutes, E, Valgañón, M, Cigudosa, J C, Bengoechea, E, Calasanz, M J

Get full text

JAK2-V617F activating mutation in acute myeloid leukemia: prognostic impact and association with other molecular markers by Lahortiga, I, Calasanz, M.J, Conchillo, A, Vicente, C, Vazquez, I, Carranza, C, Cristobal, I, Bandres, E, Odero, M.d, Marcotegui, N, Rivell, G

Get full text