Search Results - "Oderberg, Isaac M"
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Hepatic Nervous System in Development, Regeneration, and Disease
Published in Hepatology (Baltimore, Md.) (01-12-2021)“…The liver is innervated by autonomic and sensory fibers of the sympathetic and parasympathetic nervous systems that regulate liver function, regeneration, and…”
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Biliary epithelial cells are facultative liver stem cells during liver regeneration in adult zebrafish
Published in JCI insight (10-01-2023)“…The liver is a highly regenerative organ, yet the presence of a dedicated stem cell population remains controversial. Here, we interrogate a severe hepatocyte…”
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activin-2 is required for regeneration of polarity on the planarian anterior-posterior axis
Published in PLoS genetics (29-03-2021)“…Planarians are flatworms and can perform whole-body regeneration. This ability involves a mechanism to distinguish between anterior-facing wounds that require…”
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Embryonic alcohol exposure disrupts the ubiquitin-proteasome system
Published in JCI insight (08-12-2022)“…Ethanol (EtOH) is a commonly encountered teratogen that can disrupt organ development and lead to fetal alcohol spectrum disorders (FASDs); many mechanisms of…”
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Planarian Epidermal Stem Cells Respond to Positional Cues to Promote Cell-Type Diversity
Published in Developmental cell (13-03-2017)“…Successful regeneration requires that progenitors of different lineages form the appropriate missing cell types. However, simply generating lineages is not…”
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Cellular and Molecular Responses Unique to Major Injury Are Dispensable for Planarian Regeneration
Published in Cell reports (Cambridge) (27-11-2018)“…The fundamental requirements for regeneration are poorly understood. Planarians can robustly regenerate all tissues after injury, involving stem cells,…”
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Fetal alcohol spectrum disorder predisposes to metabolic abnormalities in adulthood
Published in The Journal of clinical investigation (01-05-2020)“…Prenatal alcohol exposure (PAE) affects at least 10% of newborns globally and leads to the development of fetal alcohol spectrum disorders (FASDs). Despite its…”
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There Is Something Fishy About Liver Cancer: Zebrafish Models of Hepatocellular Carcinoma
Published in Cellular and molecular gastroenterology and hepatology (01-01-2019)“…The incidence of hepatocellular carcinoma (HCC) and the mortality resulting from HCC are both increasing. Most patients with HCC are diagnosed at advanced…”
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foxF-1 Controls Specification of Non-body Wall Muscle and Phagocytic Cells in Planarians
Published in Current biology (03-12-2018)“…Planarians are flatworms capable of regenerating any missing body part in a process requiring stem cells and positional information. Muscle is a major source…”
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Landmarks in Existing Tissue at Wounds Are Utilized to Generate Pattern in Regenerating Tissue
Published in Current biology (06-03-2017)“…Regeneration in many organisms involves the formation of a blastema, which differentiates and organizes into the appropriate missing tissues. How blastema…”
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There Is Something Fishy About Liver Cancer: Zebrafish Models of Hepatocellular CarcinomaSummary
Published in Cellular and molecular gastroenterology and hepatology (01-01-2019)“…The incidence of hepatocellular carcinoma (HCC) and the mortality resulting from HCC are both increasing. Most patients with HCC are diagnosed at advanced…”
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