Search Results - "Oddos, Thierry"
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Skin toxicity of surfactants: Structure/toxicity relationships
Published in Colloids and surfaces. A, Physicochemical and engineering aspects (01-03-2015)“…•Skin irritancy of surfactants is related to their physico-chemical properties.•Surfactants can be split into two well-separated classes: toxic and mild.•Ionic…”
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ORAI1 calcium channel orchestrates skin homeostasis
Published in Proceedings of the National Academy of Sciences - PNAS (10-12-2013)“…To achieve and maintain skin architecture and homeostasis, keratinocytes must intricately balance growth, differentiation, and polarized motility known to be…”
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A purified Feverfew extract protects from oxidative damage by inducing DNA repair in skin cells via a PI3-kinase-dependent Nrf2/ARE pathway
Published in Journal of dermatological science (01-12-2013)“…Abstract Background Environmental factors such as solar ultraviolet (UV) radiation and other external aggressors provide an oxidative challenge that is…”
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Surfactants have multi-fold effects on skin barrier function
Published in EJD. European journal of dermatology (01-09-2015)“…Background The stratum corneum (SC) is responsible for the barrier properties of the skin and the role of intercorneocyte skin lipids, particularly their…”
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T-plastin expression downstream to the calcineurin/NFAT pathway is involved in keratinocyte migration
Published in PloS one (16-09-2014)“…Cutaneous wound healing requires keratinocyte proliferation, migration and differentiation to restore the barrier function of the skin. The calcineurin/nuclear…”
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In Vitro Differentiation of Human Skin-Derived Cells into Functional Sensory Neurons-Like
Published in Cells (Basel, Switzerland) (17-04-2020)“…Skin-derived precursor cells (SKPs) are neural crest stem cells that persist in certain adult tissues, particularly in the skin. They can generate a large type…”
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The role of the skin barrier in modulating the effects of common skin microbial species on the inflammation, differentiation and proliferation status of epidermal keratinocytes
Published in BMC research notes (18-11-2013)“…Skin resident microbial species are often thought of either as pathogenic or commensal. However, little is known about the role of the skin barrier in…”
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Human Collagen Krox Up-regulates Type I Collagen Expression in Normal and Scleroderma Fibroblasts through Interaction with Sp1 and Sp3 Transcription Factors
Published in The Journal of biological chemistry (02-11-2007)“…Despite several investigations, the transcriptional mechanisms that regulate the expression of both type I collagen genes (COL1A1 and COL1A2) in either…”
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Deciphering the Role of Skin Surface Microbiome in Skin Health: An Integrative Multiomics Approach Reveals Three Distinct Metabolite‒Microbe Clusters
Published in Journal of investigative dermatology (01-02-2022)“…The advent of 16S RNA profiling and shotgun metagenomics has enabled a holistic approach to the study of the skin microbiome composition. Despite the…”
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33559 Skin maturation processes observed in infants extend well into the childhood period
Published in Journal of the American Academy of Dermatology (01-09-2022)Get full text
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Skin maturation from birth to 10years of age: Structure, function, composition and microbiome
Published in Experimental dermatology (01-09-2023)“…Infant and adult skin physiology differ in many ways; however, limited data exist for older children. To further investigate the maturation processes of…”
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Skin maturation from birth to 10 years of age: Structure, function, composition and microbiome
Published in Experimental dermatology (01-09-2023)“…Infant and adult skin physiology differ in many ways; however, limited data exist for older children. To further investigate the maturation processes of…”
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Early skin inflammatory biomarker is predictive of development and persistence of atopic dermatitis in infants
Published in Journal of allergy and clinical immunology (01-06-2024)“…The Short-Term Topical Application for Prevention of Atopic Dermatitis (STOP AD) study, a randomized, open-label trial evaluating the effect of short-term…”
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Phenotypic and functional changes in dermal primary fibroblasts isolated from intrinsically aged human skin
Published in Experimental dermatology (01-02-2016)“…Dermal fibroblasts play a key role in maintaining skin homoeostasis by synthesizing and degrading extracellular matrix components. During ageing, they are…”
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NF-κB Accumulation Associated with COL1A1 Transactivators Defects during Chronological Aging Represses Type I Collagen Expression through a –112/–61-bp Region of the COL1A1 Promoter in Human Skin Fibroblasts
Published in Journal of investigative dermatology (01-10-2012)“…The aging process, especially of the skin, is governed by changes in the epidermal, dermo-epidermal, and dermal compartments. Type I collagen, which is the…”
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A Predictive Self-Organizing Multicellular Computational Model of Infant Skin Permeability to Topically Applied Substances
Published in Journal of investigative dermatology (01-08-2021)“…Computational models of skin permeability are typically based on assumptions of fixed geometry and homogeneity of the whole epidermis or of epidermal strata…”
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An integrative multi‐omic analysis reveals a major metabolic rewiring between baby foreskin keratinocytes and adult female abdominal keratinocytes
Published in Experimental dermatology (01-04-2022)“…Even though its development starts early in utero, neonatal skin is still immature at birth relative to adult and undergoes a maturation process extending to…”
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Retinoic Acid Increases Aquaporin 3 Expression in Normal Human Skin
Published in Journal of investigative dermatology (01-03-2008)“…We have investigated the effects of all-trans retinoic acid (ATRA) on aquaporin 3 (AQP3) expression and function both in vitro and ex vivo. ATRA treatment…”
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