Search Results - "Odden, Anthony R."
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Divergent roles of IL-23 and IL-12 in host defense against Klebsiella pneumoniae
Published in The Journal of experimental medicine (19-09-2005)“…Interleukin (IL)-23 is a heterodimeric cytokine that shares the identical p40 subunit as IL-12 but exhibits a unique p19 subunit similar to IL-12 p35. IL-12/23…”
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Efficient discovery of DNA polymorphisms in natural populations by Ecotilling
Published in The Plant journal : for cell and molecular biology (01-03-2004)“…Summary We have adapted the mutation detection technology used in Targeting Induced Local Lesions in Genomes (TILLING) to the discovery of polymorphisms in…”
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Spectrum of Chemically Induced Mutations From a Large-Scale Reverse-Genetic Screen in Arabidopsis
Published in Genetics (Austin) (01-06-2003)“…Chemical mutagenesis has been the workhorse of traditional genetics, but it has not been possible to determine underlying rates or distributions of mutations…”
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Discovery of induced point mutations in maize genes by TILLING
Published in BMC plant biology (28-07-2004)“…Going from a gene sequence to its function in the context of a whole organism requires a strategy for targeting mutations, referred to as reverse genetics…”
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Pulmonary Interleukin-23 Gene Delivery Increases Local T-Cell Immunity and Controls Growth of Mycobacterium tuberculosis in the Lungs
Published in Infection and Immunity (01-09-2005)“…Interleukin-23 (IL-23) is a heterodimeric cytokine that shares IL-12 p40 but contains a unique p19 subunit similar to IL-12 p35. Previous studies indicate a…”
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Large-scale discovery of induced point mutations with high-throughput TILLING
Published in Genome research (01-03-2003)“…TILLING (Targeting Induced Local Lesions in Genomes) is a general reverse-genetic strategy that provides an allelic series of induced point mutations in genes…”
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Acute Alcohol Intoxication Suppresses the Interleukin 23 Response to Klebsiella pneumoniae Infection
Published in Alcoholism, clinical and experimental research (01-07-2006)“…Background: Bacterial pneumonia is a widely recognized infection in the alcohol‐abusing patient. Interleukin 23 (IL‐23) is a recently described cytokine…”
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Ethanol Exposure Impairs LPS-Induced Pulmonary LIX Expression: Alveolar Epithelial Cell Dysfunction as a Consequence of Acute Intoxication
Published in Alcoholism, clinical and experimental research (01-02-2009)“…Background: Alcohol intoxication impairs innate immune responses to bacterial pneumonia, including neutrophil influx. Lipopolysaccharide (LPS)‐induced…”
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Acute alcohol intoxication suppresses the pulmonary ELR-negative CXC chemokine response to lipopolysaccharide
Published in Alcohol (Fayetteville, N.Y.) (01-08-2007)“…Abstract Alcohol abuse impairs the pulmonary immune response to infection and increases the morbidity and mortality of bacterial pneumonia. Acute alcohol…”
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