Search Results - "Odales, Josué"
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1
Immunogenic properties of immunoglobulin superfamily members within complex biological networks
Published in Cellular immunology (01-12-2020)“…•Antibody-based therapies induce CDR-specific T and B cell responses.•Idiotype-anti-idiotype network alters immune system memory compartment.•Antigenized…”
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Antitumor efficacy of MUC1-derived variable epitope library treatments in a mouse model of breast cancer
Published in Vaccine (05-08-2022)“…•MUC1 signal peptide-derived Variable Epitope Libraries show antitumor effects.•Vaccination induces a pool of CD8+ T cells which recognize most variant…”
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Generation of cancer vaccine immunogens derived from Oncofetal antigen (OFA/iLRP) using variable epitope libraries tested in an aggressive breast cancer model
Published in Molecular immunology (01-11-2021)“…•Variable Epitope Library (VEL) carries a large number of epitope variants.•The VELs derived from oncofetal OFA/iLRP inhibited tumor growth and metastasis.•The…”
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Tumor antigen-unbiased variable epitope library contains mimotopes with antitumor effect in a mouse model of breast cancer
Published in Molecular immunology (01-05-2023)“…Breast cancer is one of the leading causes of death that affects the female population worldwide. Despite advances in treatments and a greater understanding of…”
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Generation of multiepitope cancer vaccines based on large combinatorial libraries of survivin‐derived mutant epitopes
Published in Immunology (01-10-2020)“…We developed a novel vaccine approach based on a new class of vaccine immunogens, called variable epitope libraries (VELs). We showed significant tumor growth…”
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Genomic instability, origin and evolution of cancer, and personalized immunotherapy
Published in Vacunas (Barcelona. Internet. English ed.) (01-09-2022)“…Cancer is a set of related diseases of genetic origin characterised by a high genetic and/or antigenic variability. Identification of tumour-specific antigens…”
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Inestabilidad genética, origen y evolución del cáncer y la inmunoterapia personalizada
Published in Vacunas (01-09-2022)“…El cáncer es un conjunto de enfermedades relacionadas de origen genético que se caracterizan por una alta variabilidad genética y/o antigénica. La…”
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