Search Results - "Oda, Toshiyuki"

A molecular ruler determines the repeat length in eukaryotic cilia and flagella by Oda, Toshiyuki, Yanagisawa, Haruaki, Kamiya, Ritsu, Kikkawa, Masahide

“…Existence of cellular structures with specific size raises a fundamental question in biology: How do cells measure length? One conceptual answer to this…”
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Three-dimensional structural labeling microscopy of cilia and flagella by Oda, Toshiyuki

“…Locating a molecule within a cell using protein-tagging and immunofluorescence is a fundamental technique in cell biology, whereas in three-dimensional…”
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Electrostatic interaction between polyglutamylated tubulin and the nexin-dynein regulatory complex regulates flagellar motility by Kubo, Tomohiro, Oda, Toshiyuki

“…Tubulins undergo various posttranslational modifications. Among them, polyglutamylation is involved in the motility of eukaryotic flagella and the stability of…”
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Mechanosignaling between central apparatus and radial spokes controls axonemal dynein activity by Oda, Toshiyuki, Yanagisawa, Haruaki, Yagi, Toshiki, Kikkawa, Masahide

“…Cilia/flagella are conserved organelles that generate fluid flow in eukaryotes. The bending motion of flagella requires concerted activity of dynein motors…”
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Origin and Evolutionary Alteration of the Mitochondrial Import System in Eukaryotic Lineages by Fukasawa, Yoshinori, Oda, Toshiyuki, Tomii, Kentaro, Imai, Kenichiro

“…Protein transport systems are fundamentally important for maintaining mitochondrial function. Nevertheless, mitochondrial protein translocases such as the…”
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Cryo-EM structures of cardiac thin filaments reveal the 3D architecture of troponin by Oda, Toshiyuki, Yanagisawa, Haruaki, Wakabayashi, Takeyuki

“…[Display omitted] •Cryo-EM revealed the detailed 3D structure of the cardiac thin filament.•Orientation of troponin differed from the classical model by…”
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Disease-associated mutations hyperactivate KIF1A motility and anterograde axonal transport of synaptic vesicle precursors by Chiba, Kyoko, Takahashi, Hironori, Chen, Min, Obinata, Hiroyuki, Arai, Shogo, Hashimoto, Koichi, Oda, Toshiyuki, McKenney, Richard J., Niwa, Shinsuke

“…KIF1A is a kinesin family motor involved in the axonal transport of synaptic vesicle precursors (SVPs) along microtubules (MTs). In humans, more than 10 point…”
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Systematic studies of all PIH proteins in zebrafish reveal their distinct roles in axonemal dynein assembly by Yamaguchi, Hiroshi, Oda, Toshiyuki, Kikkawa, Masahide, Takeda, Hiroyuki

“…Construction of motile cilia/flagella requires cytoplasmic preassembly of axonemal dyneins before transport into cilia. Axonemal dyneins have various subtypes,…”
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Detailed structural and biochemical characterization of the nexin-dynein regulatory complex by Oda, Toshiyuki, Yanagisawa, Haruaki, Kikkawa, Masahide

“…The nexin-dynein regulatory complex (N-DRC) forms a cross-bridge between the outer doublet microtubules of the axoneme and regulates dynein motor activity in…”
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Novel structural labeling method using cryo-electron tomography and biotin-streptavidin system by Oda, Toshiyuki, Kikkawa, Masahide

“…There are a number of large macromolecular complexes that play important roles in the cell, and identifying the positions of their components is a key step to…”
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Cryo-electron tomography of Birbeck granules reveals the molecular mechanism of langerin lattice formation by Oda, Toshiyuki, Yanagisawa, Haruaki, Shinmori, Hideyuki, Ogawa, Youichi, Kawamura, Tatsuyoshi

“…Langerhans cells are specialized antigen-presenting cells localized within the epidermis and mucosal epithelium. Upon contact with Langerhans cells, pathogens…”
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Simple adjustment of the sequence weight algorithm remarkably enhances PSI-BLAST performance by Oda, Toshiyuki, Lim, Kyungtaek, Tomii, Kentaro

“…PSI-BLAST, an extremely popular tool for sequence similarity search, features the utilization of Position-Specific Scoring Matrix (PSSM) constructed from a…”
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Structure and function of outer dynein arm intermediate and light chain complex by Oda, Toshiyuki, Abe, Tatsuki, Yanagisawa, Haruaki, Kikkawa, Masahide

“…The outer dynein arm (ODA) is a molecular complex that drives the beating motion of cilia/flagella. Chlamydomonas ODA is composed of three heavy chains (HCs),…”
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Chlamydomonas FAP70 is a component of the previously uncharacterized ciliary central apparatus projection C2a by Hou, Yuqing, Zhao, Lei, Kubo, Tomohiro, Cheng, Xi, McNeill, Nathan, Oda, Toshiyuki, Witman, George B

“…Cilia are essential organelles required for cell signaling and motility. Nearly all motile cilia have a '9+2' axoneme composed of nine outer doublet…”
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Template‐based quaternary structure prediction of proteins using enhanced profile–profile alignments by Nakamura, Tsukasa, Oda, Toshiyuki, Fukasawa, Yoshinori, Tomii, Kentaro

“…Proteins often exist as their multimeric forms when they function as so‐called biological assemblies consisting of the specific number and arrangement of…”
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Identification of the Outer-Inner Dynein Linker as a Hub Controller for Axonemal Dynein Activities by Oda, Toshiyuki, Yagi, Toshiki, Yanagisawa, Haruaki, Kikkawa, Masahide

“…In flagella, the outer dynein arm (ODA) and inner dynein arm (IDA) play distinct roles in generating beating motion. However, functional communications between…”
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Chlamydomonas as a tool to study tubulin polyglutamylation by Kubo, Tomohiro, Oda, Toshiyuki

“…α- and β-tubulin undergoes polyglutamylation, a post-translational modification. This modification is important for stability and electrostatic properties of…”
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Cryo-EM elucidates the uroplakin complex structure within liquid-crystalline lipids in the porcine urothelial membrane by Yanagisawa, Haruaki, Kita, Yoshihiro, Oda, Toshiyuki, Kikkawa, Masahide

“…The urothelium, a distinct epithelial tissue lining the urinary tract, serves as an essential component in preserving urinary tract integrity and thwarting…”
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CFAP70 Is a Novel Axoneme-Binding Protein That Localizes at the Base of the Outer Dynein Arm and Regulates Ciliary Motility by Shamoto, Noritoshi, Narita, Keishi, Kubo, Tomohiro, Oda, Toshiyuki, Takeda, Sen

“…In the present study, we characterized CFAP70, a candidate of cilia-related protein in mice. As this protein has a cluster of tetratricopeptide repeat (TPR)…”
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Interactions between mitochondria and endoplasmic reticulum in demyelinated axons by Thai, Truc Quynh, Nguyen, Huy Bang, Sui, Yang, Ikenaka, Kazuhiro, Oda, Toshiyuki, Ohno, Nobuhiko

“…Demyelination leads to axonal changes that involve the functions and dynamics of axonal mitochondria supporting metabolism and survival of axons. However, the…”
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