Search Results - "Oda, Sayaka"
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1
Purinergic P2Y receptors: Molecular diversity and implications for treatment of cardiovascular diseases
Published in Pharmacology & therapeutics (Oxford) (01-12-2017)“…Purinergic signaling, mediated mainly by G protein-coupled P2Y receptors (P2YRs), is now attracting attention as a new therapeutic target for preventing or…”
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2
Brazilian Green Propolis Promotes Weight Loss and Reduces Fat Accumulation in C57BL/6 Mice Fed A High-Fat Diet
Published in Biological & pharmaceutical bulletin (2017)“…Propolis is a bee product with various biological properties. C57BL/6 mice were fed a high-fat diet and treated with propolis for 14 weeks. Body weight in mice…”
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3
TRPC3-Nox2 axis mediates nutritional deficiency-induced cardiomyocyte atrophy
Published in Scientific reports (05-07-2019)“…Myocardial atrophy, characterized by the decreases in size and contractility of cardiomyocytes, is caused by severe malnutrition and/or mechanical unloading…”
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4
How can heatstroke damage the brain? A mini review
Published in Frontiers in neuroscience (10-10-2024)“…Record-breaking heat waves over the past 20 years have led to a global increase in heat-related deaths, including heatstroke. Heat-related illnesses occur when…”
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5
Myocardial TRPC6-mediated Zn2+ influx induces beneficial positive inotropy through β-adrenoceptors
Published in Nature communications (26-10-2022)“…Baroreflex control of cardiac contraction (positive inotropy) through sympathetic nerve activation is important for cardiocirculatory homeostasis. Transient…”
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6
Bacterial sepsis causes more dramatic pathogenetic changes in the Th1 pathway than does viral (COVID-19) sepsis: a prospective observational study of whole blood transcriptomes
Published in Virology journal (19-08-2024)“…This study aimed to comprehensively compare host responses of patients with bacterial sepsis and those with viral (COVID-19) sepsis by analyzing messenger RNA…”
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7
T cell dysfunction in elderly ARDS patients based on miRNA and mRNA integration analysis
Published in Frontiers in immunology (20-03-2024)“…Acute respiratory distress syndrome (ARDS) is respiratory failure that commonly occurs in critically ill patients, and the molecular mechanisms underlying its…”
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8
TRPC6 counteracts TRPC3-Nox2 protein complex leading to attenuation of hyperglycemia-induced heart failure in mice
Published in Scientific reports (08-08-2017)“…Excess production of reactive oxygen species (ROS) caused by hyperglycemia is a major risk factor for heart failure. We previously reported that transient…”
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9
TRPC5-eNOS Axis Negatively Regulates ATP-Induced Cardiomyocyte Hypertrophy
Published in Frontiers in pharmacology (22-05-2018)“…Cardiac hypertrophy, induced by neurohumoral factors, including angiotensin II and endothelin-1, is a major predisposing factor for heart failure. These…”
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10
TRPC3 Channels in Cardiac Fibrosis
Published in Frontiers in cardiovascular medicine (07-09-2017)“…Cardiac stiffness, caused by interstitial fibrosis due to deposition of extracellular matrix proteins, is thought as a major clinical outcome of heart failure…”
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11
運動模倣薬の新たなストラテジー
Published in YAKUGAKU ZASSHI (01-10-2018)“…「1. はじめに」適度な運動が心血管疾患やうつ病を始めとする様々な疾患に対して有効であることが報告されている. しかし, 運動療法は加齢や症状の重篤さにより適用できない患者も多い. そのため, 運動療法を模倣する新しい薬剤開発のニーズは高く, 世界的にも研究が進められている. 心臓は, 骨格筋や血管平滑筋と同様,…”
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12
TRPC6 regulates phenotypic switching of vascular smooth muscle cells through plasma membrane potential‐dependent coupling with PTEN
Published in The FASEB journal (01-09-2019)“…ABSTRACTVascular smooth muscle cells (VSMCs) play critical roles in the stability and tonic regulation of vascular homeostasis. VSMCs can switch back and forth…”
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13
TRPC channels in exercise-mimetic therapy
Published in Pflügers Archiv (01-03-2019)“…Physical exercise yields beneficial effects on all types of muscle cells, which are essential for the maintenance of cardiovascular homeostasis and good blood…”
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14
Interspecific differences in the recovery of rocky intertidal zonation after the 2011 Great East Japan Earthquake
Published in Ecological research (01-01-2020)“…Both natural and anthropogenic disturbances have significant impacts on populations in terrestrial and marine habitats. Despite evidence that population…”
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15
New Strategies for Exercise-Mimetic Medication
Published in YAKUGAKU ZASSHI (01-10-2018)“…Moderate exercise has been reported to combat several diseases, including cardiovascular diseases and depressants. However, many patients do not have ability…”
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16
TRPC3-Nox2 complex mediates doxorubicin-induced myocardial atrophy
Published in JCI insight (03-08-2017)“…Myocardial atrophy is a wasting of cardiac muscle due to hemodynamic unloading. Doxorubicin is a highly effective anticancer agent but also induces myocardial…”
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17
Myocardial TRPC6-mediated Zn 2+ influx induces beneficial positive inotropy through β-adrenoceptors
Published in Nature communications (26-10-2022)“…Baroreflex control of cardiac contraction (positive inotropy) through sympathetic nerve activation is important for cardiocirculatory homeostasis. Transient…”
Get full text
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18
Current Limiting Experiment of Transformer Type Superconducting Fault Current Limiter With Rewound Structure Using BSCCO Wire in Small Model Power System
Published in IEEE transactions on applied superconductivity (01-06-2011)“…Superconducting fault current limiters (SFCLs) are expected to improve the reliability and stability of power systems. We have proposed new design of a…”
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