Search Results - "Octavio Ramilo"

Mapping systemic lupus erythematosus heterogeneity at the single-cell level by Nehar-Belaid, Djamel, Hong, Seunghee, Marches, Radu, Chen, Guo, Bolisetty, Mohan, Baisch, Jeanine, Walters, Lynnette, Punaro, Marilynn, Rossi, Robert J., Chung, Cheng-Han, Huynh, Richie P., Singh, Prashant, Flynn, William F., Tabanor-Gayle, Joy-Ann, Kuchipudi, Navya, Mejias, Asuncion, Collet, Magalie A., Lucido, Anna Lisa, Palucka, Karolina, Robson, Paul, Lakshminarayanan, Santhanam, Ramilo, Octavio, Wright, Tracey, Pascual, Virginia, Banchereau, Jacques F.

“…Patients with systemic lupus erythematosus (SLE) display a complex blood transcriptome whose cellular origin is poorly resolved. Using single-cell RNA…”
Get full text

Respiratory Syncytial Virus Seasonality: A Global Overview by Obando-Pacheco, Pablo, Justicia-Grande, Antonio José, Rivero-Calle, Irene, Rodríguez-Tenreiro, Carmen, Sly, Peter, Ramilo, Octavio, Mejías, Asunción, Baraldi, Eugenio, Papadopoulos, Nikolaos G, Nair, Harish, Nunes, Marta C, Kragten-Tabatabaie, Leyla, Heikkinen, Terho, Greenough, Anne, Stein, Renato T, Manzoni, Paolo, Bont, Louis, Martinón-Torres, Federico

“…Abstract Respiratory syncytial virus (RSV) is the leading cause of acute lower respiratory infections in children. By the age of 1 year, 60%–70% of children…”
Get full text

Host transcriptomics for diagnosis of infectious diseases: one step closer to clinical application by Ramilo, Octavio, Mejias, Asuncion

“…One of the most common and challenging situations that physicians face in their daily clinical practice is the diagnosis and management of patients with acute…”
Get full text

Lower respiratory tract infection caused by respiratory syncytial virus: current management and new therapeutics by Mazur, Natalie I, BA, Martinón-Torres, Federico, Prof, Baraldi, Eugenio, Prof, Fauroux, Brigitte, Prof, Greenough, Anne, Prof, Heikkinen, Terho, Prof, Manzoni, Paolo, Prof, Mejias, Asuncion, Prof, Nair, Harish, Prof, Papadopoulos, Nikolaos G, Prof, Polack, Fernando P, Prof, Ramilo, Octavio, Prof, Sharland, Mike, Prof, Stein, Renato, Prof, Madhi, Shabir A, Prof, Bont, Louis, Prof

“…Summary Respiratory syncytial virus (RSV) is a major worldwide cause of morbidity and mortality in children under five years of age. Evidence-based management…”
Get full text

The respiratory syncytial virus vaccine landscape: lessons from the graveyard and promising candidates by Mazur, Natalie I, Higgins, Deborah, Nunes, Marta C, Melero, José A, Langedijk, Annefleur C, Horsley, Nicole, Buchholz, Ursula J, Openshaw, Peter J, McLellan, Jason S, Englund, Janet A, Mejias, Asuncion, Karron, Ruth A, Simões, Eric AF, Knezevic, Ivana, Ramilo, Octavio, Piedra, Pedro A, Chu, Helen Y, Falsey, Ann R, Nair, Harish, Kragten-Tabatabaie, Leyla, Greenough, Anne, Baraldi, Eugenio, Papadopoulos, Nikolaos G, Vekemans, Johan, Polack, Fernando P, Powell, Mair, Satav, Ashish, Walsh, Edward E, Stein, Renato T, Graham, Barney S, Bont, Louis J

“…The global burden of disease caused by respiratory syncytial virus (RSV) is increasingly recognised, not only in infants, but also in older adults (aged ≥65…”
Get full text

Differences in SARS-CoV-2 Clinical Manifestations and Disease Severity in Children and Adolescents by Infecting Variant by Quintero, Ana Maria, Eisner, Mariah, Sayegh, Rouba, Wright, Tori, Ramilo, Octavio, Leber, Amy L, Wang, Huanyu, Mejias, Asuncion

“…Since the COVID-19 pandemic began, different SARS-CoV-2 variants have been identified and associated with higher transmissibility than the ancestral nonvariant…”
Get full text

Development of a fixed module repertoire for the analysis and interpretation of blood transcriptome data by Altman, Matthew C., Rinchai, Darawan, Baldwin, Nicole, Toufiq, Mohammed, Whalen, Elizabeth, Garand, Mathieu, Syed Ahamed Kabeer, Basirudeen, Alfaki, Mohamed, Presnell, Scott R., Khaenam, Prasong, Ayllón-Benítez, Aaron, Mougin, Fleur, Thébault, Patricia, Chiche, Laurent, Jourde-Chiche, Noemie, Phillips, J. Theodore, Klintmalm, Goran, O’Garra, Anne, Berry, Matthew, Bloom, Chloe, Wilkinson, Robert J., Graham, Christine M., Lipman, Marc, Lertmemongkolchai, Ganjana, Bedognetti, Davide, Thiebaut, Rodolphe, Kheradmand, Farrah, Mejias, Asuncion, Ramilo, Octavio, Palucka, Karolina, Pascual, Virginia, Banchereau, Jacques, Chaussabel, Damien

“…As the capacity for generating large-scale molecular profiling data continues to grow, the ability to extract meaningful biological knowledge from it remains a…”
Get full text

The larger attachment glycoprotein of respiratory syncytial virus produced in primary human bronchial epithelial cultures reduces infectivity for cell lines by King, Tiffany, Mejias, Asuncion, Ramilo, Octavio, Peeples, Mark E

“…Respiratory syncytial virus (RSV) infects the upper and lower respiratory tracts and can cause lower respiratory tract infections in children and elders. RSV…”
Get full text

Accuracy of the Urinalysis for Urinary Tract Infections in Febrile Infants 60 Days and Younger by Tzimenatos, Leah, Mahajan, Prashant, Dayan, Peter S, Vitale, Melissa, Linakis, James G, Blumberg, Stephen, Borgialli, Dominic, Ruddy, Richard M, Van Buren, John, Ramilo, Octavio, Kuppermann, Nathan

“…Reports of the test accuracy of the urinalysis for diagnosing urinary tract infections (UTIs) in young febrile infants have been variable. We evaluated the…”
Get full text

Whole blood gene expression profiles to assess pathogenesis and disease severity in infants with respiratory syncytial virus infection by Mejias, Asuncion, Dimo, Blerta, Suarez, Nicolas M, Garcia, Carla, Suarez-Arrabal, M Carmen, Jartti, Tuomas, Blankenship, Derek, Jordan-Villegas, Alejandro, Ardura, Monica I, Xu, Zhaohui, Banchereau, Jacques, Chaussabel, Damien, Ramilo, Octavio

“…Respiratory syncytial virus (RSV) is the leading cause of viral lower respiratory tract infection (LRTI) and hospitalization in infants. Mostly because of the…”
Get full text

Infliximab for intensification of primary therapy for Kawasaki disease: a phase 3 randomised, double-blind, placebo-controlled trial by Tremoulet, Adriana H, Dr, Jain, Sonia, PhD, Jaggi, Preeti, MD, Jimenez-Fernandez, Susan, MD, Pancheri, Joan M, RN, Sun, Xiaoying, MS, Kanegaye, John T, MD, Kovalchin, John P, MD, Printz, Beth F, MD, Ramilo, Octavio, Prof, Burns, Jane C, Prof

“…Summary Background Kawasaki disease, the most common cause of acquired heart disease in developed countries, is a self-limited vasculitis that is treated with…”
Get full text

Macrolide-Resistant Mycoplasma pneumoniae Infections in Children, Ohio, USA by Lanata, Mariana M, Wang, Huanyu, Everhart, Kathy, Moore-Clingenpeel, Melisa, Ramilo, Octavio, Leber, Amy

“…Emergence of macrolide-resistant Mycoplasma pneumoniae (MRMp) challenges empiric macrolide therapy. Our goal was to determine MRMp rates and define…”
Get full text

Blood genome expression profiles in infants with congenital cytomegalovirus infection by Ouellette, Christopher P., Sánchez, Pablo J., Xu, Zhaohui, Blankenship, Derek, Zeray, Fiker, Ronchi, Andrea, Shimamura, Masako, Chaussabel, Damien, Lee, Lizette, Owen, Kris E., Shoup, Angela G., Ramilo, Octavio, Mejias, Asuncion

“…Congenital CMV infection (cCMVi) affects 0.5–1% of all live births worldwide, making it the leading cause of sensorineural hearing loss (SNHL) in childhood…”
Get full text

Respiratory Syncytial Virus (RSV)–Specific Antibodies in Pregnant Women and Subsequent Risk of RSV Hospitalization in Young Infants by Koivisto, Karoliina, Nieminen, Tea, Mejias, Asuncion, Capella Gonzalez, Cristina, Ye, Fang, Mertz, Sara, Peeples, Mark, Ramilo, Octavio, Saxén, Harri

“…Abstract Background The fusion (F) glycoprotein of respiratory syncytial virus (RSV) represents the major neutralizing antigen, and antibodies against the…”
Get full text

Plasticity and Virus Specificity of the Airway Epithelial Cell Immune Response during Respiratory Virus Infection by LOANNIDIS, Loannis, MCNALLY, Beth, WILLETTE, Meredith, PEEPLES, Mark E, CHAUSSABEL, Damien, DURBIN, Joan E, RAMILO, Octavio, MEJIAS, Asuncion, FLANO, Emilio

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Key clinical research priorities for the pediatric community during the COVID-19 pandemic by Noel, Gary J., Davis, Jonathan M., Ramilo, Octavio, Bradley, John S., Connor, Edward

Get full text

Infant Immune Response to Respiratory Viral Infections by Heinonen, Santtu, MD, PhD, Rodriguez-Fernandez, Rosa, MD, PhD, Diaz, Alejandro, MD, Rodriguez-Pastor, Silvia Oliva, MD, Ramilo, Octavio, MD, Mejias, Asuncion, MD, PhD

“…Of all respiratory viruses that affect infants, respiratory syncytial virus (RSV) and rhinovirus (RV) represent the leading pathogens causing acute disease…”
Get full text

Infliximab Treatment of Intravenous Immunoglobulin–Resistant Kawasaki Disease by Burns, Jane C., MD, Best, Brookie M., PharmD, MAS, Mejias, Asuncion, MD, Mahony, Lynn, MD, Fixler, David E., MD, Jafri, Hasan S., MD, Melish, Marian E., MD, Jackson, Mary Anne, MD, Asmar, Basim I., MD, Lang, David J., MD, Connor, James D., MD, Capparelli, Edmund V., PharmD, Keen, Monica L., BS, Mamun, Khalid, BS, Keenan, Gregory F., MD, Ramilo, Octavio, MD

“…Objective To investigate the safety, tolerability, and pharmacokinetics of the anti–tumor necrosis factor-α monoclonal antibody infliximab in subjects with…”
Get full text

Whole blood transcriptional profiles as a prognostic tool in complete and incomplete Kawasaki Disease by Jaggi, Preeti, Mejias, Asuncion, Xu, Zhaohui, Yin, Han, Moore-Clingenpeel, Melissa, Smith, Bennett, Burns, Jane C, Tremoulet, Adriana H, Jordan-Villegas, Alejandro, Chaussabel, Damien, Texter, Karen, Pascual, Virginia, Ramilo, Octavio

“…Early identification of children with Kawasaki Disease (KD) is key for timely initiation of intravenous immunoglobulin (IVIG) therapy. However, the diagnosis…”
Get full text

Young infants display heterogeneous serological responses and extensive but reversible transcriptional changes following initial immunizations by Nouri, Nima, Cao, Raquel Giacomelli, Bunsow, Eleonora, Nehar-Belaid, Djamel, Marches, Radu, Xu, Zhaohui, Smith, Bennett, Heinonen, Santtu, Mertz, Sara, Leber, Amy, Smits, Gaby, van der Klis, Fiona, Mejías, Asunción, Banchereau, Jacques, Pascual, Virginia, Ramilo, Octavio

“…Infants necessitate vaccinations to prevent life-threatening infections. Our understanding of the infant immune responses to routine vaccines remains limited…”
Get full text