Search Results - "Ocone, Andrea"
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1
Reconstructing gene regulatory dynamics from high-dimensional single-cell snapshot data
Published in Bioinformatics (Oxford, England) (15-06-2015)“…High-dimensional single-cell snapshot data are becoming widespread in the systems biology community, as a mean to understand biological processes at the…”
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Journal Article -
2
A stochastic hybrid model of a biological filter
Published in Electronic proceedings in theoretical computer science (22-08-2013)“…We present a hybrid model of a biological filter, a genetic circuit which removes fast fluctuations in the cell's internal representation of the extra cellular…”
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Journal Article -
3
Systems analysis of transcription factor activities in environments with stable and dynamic oxygen concentrations
Published in Open biology (01-07-2012)“…Understanding gene regulation requires knowledge of changes in transcription factor (TF) activities. Simultaneous direct measurement of numerous TF activities…”
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Journal Article -
4
A subsystems approach for parameter estimation of ODE models of hybrid systems
Published in Electronic proceedings in theoretical computer science (15-08-2012)“…We present a new method for parameter identification of ODE system descriptions based on data measurements. Our method works by splitting the system into a…”
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Journal Article -
5
Reconstructing transcription factor activities in hierarchical transcription network motifs
Published in Bioinformatics (15-10-2011)“…Motivation: A knowledge of the dynamics of transcription factors is fundamental to understand the transcriptional regulation mechanism. Nowadays, an…”
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Journal Article -
6
Hybrid regulatory models: a statistically tractable approach to model regulatory network dynamics
Published in Bioinformatics (01-04-2013)“…Computational modelling of the dynamics of gene regulatory networks is a central task of systems biology. For networks of small/medium scale, the dominant…”
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Journal Article -
7
Variational inference for gaussian-jump processes with application in gene regulation
Published 01-01-2013“…In the last decades, the explosion of data from quantitative techniques has revolutionised our understanding of biological processes. In this scenario,…”
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Dissertation -
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A stochastic hybrid model of a biological filter
Published 24-08-2013“…EPTCS 124, 2013, pp. 100-108 We present a hybrid model of a biological filter, a genetic circuit which removes fast fluctuations in the cell's internal…”
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Journal Article -
9
A subsystems approach for parameter estimation of ODE models of hybrid systems
Published 19-08-2012“…EPTCS 92, 2012, pp. 30-41 We present a new method for parameter identification of ODE system descriptions based on data measurements. Our method works by…”
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Journal Article