Search Results - "Ochiai, Koji"

Tissue Distribution of Orally Administered Prenylated Isoflavones, Glyceollins, in Sprague-Dawley Rats by Zhang, Ye, Abe, Chizumi, Ochiai, Koji, Matsui, Toshiro

“…Apart from the physiological effects of glyceollins, information regarding their tissue distribution is scarce in the literature. Thus, the aim of this study…”
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Identification of a Unique Type of Isoflavone O-Methyltransferase, GmIOMT1, Based on Multi-Omics Analysis of Soybean under Biotic Stress by Uchida, Kai, Sawada, Yuji, Ochiai, Koji, Sato, Muneo, Inaba, Jun, Hirai, Masami Yokota

“…Abstract Isoflavonoids are commonly found in leguminous plants. Glycitein is one of the isoflavones produced by soybean. The genes encoding the enzymes in the…”
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Upregulation of Piezo2 in the mesangial, renin, and perivascular mesenchymal cells of the kidney of Dahl salt-sensitive hypertensive rats and its reversal by esaxerenone by Ochiai, Koji, Mochida, Yuki, Nagase, Takashi, Fukuhara, Hiroshi, Yamaguchi, Yoshihiro, Nagase, Miki

“…The recent discovery of mechanosensitive ion channels has promoted mechanobiological research in the field of hypertension and nephrology. We previously…”
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Piezo2 expression and its alteration by mechanical forces in mouse mesangial cells and renin-producing cells by Mochida, Yuki, Ochiai, Koji, Nagase, Takashi, Nonomura, Keiko, Akimoto, Yoshihiro, Fukuhara, Hiroshi, Sakai, Tatsuo, Matsumura, George, Yamaguchi, Yoshihiro, Nagase, Miki

“…The kidney plays a central role in body fluid homeostasis. Cells in the glomeruli and juxtaglomerular apparatus sense mechanical forces and modulate glomerular…”
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Different cell imaging methods did not significantly improve immune cell image classification performance by Ogawa, Taisaku, Ochiai, Koji, Iwata, Tomoharu, Ikawa, Tomokatsu, Tsuzuki, Taku, Shiroguchi, Katsuyuki, Takahashi, Koichi

“…Developments in high-throughput microscopy have made it possible to collect huge amounts of cell image data that are difficult to analyse manually. Machine…”
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Intestinal Absorption of Prenylated Isoflavones, Glyceollins, in Sprague–Dawley Rats by Zhang, Ye, Takao, Kazuhiro, Abe, Chizumi, Sasaki, Kuni, Ochiai, Koji, Matsui, Toshiro

“…Although prenylated isoflavones or glyceollins elicit physiological effects more potent than those by isoflavones, the bioavailability remains unclear. The…”
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Automated evaluation of retinal pigment epithelium disease area in eyes with age-related macular degeneration by Motozawa, Naohiro, Miura, Takuya, Ochiai, Koji, Yamamoto, Midori, Horinouchi, Takaaki, Tsuzuki, Taku, Kanda, Genki N., Ozawa, Yosuke, Tsujikawa, Akitaka, Takahashi, Koichi, Takahashi, Masayo, Kurimoto, Yasuo, Maeda, Tadao, Mandai, Michiko

“…The retinal pigment epithelium (RPE) is essential for the survival and function of retinal photoreceptor cells. RPE dysfunction causes various retinal diseases…”
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8-Prenyl daidzein and 8-prenyl genistein from germinated soybean modulate inflammatory response in activated macrophages by Jheng, Huei-Fen, Takase, Miho, Kawarasaki, Satoko, Ni, Zheng, Mohri, Shinsuke, Hayashi, Kanako, Izumi, Atsushi, Sasaki, Kuni, Shinyama, Yu, Kwon, Jungin, Ng, Su-Ping, Takahashi, Haruya, Nomura, Wataru, Yu, Rina, Ochiai, Koji, Inoue, Kazuo, Kawada, Teruo, Goto, Tsuyoshi

“…ABSTRACT Soy isoflavones have been shown to have anti-inflammatory properties; however, the anti-inflammatory effects of isoflavone metabolites produced during…”
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Endocrine therapy-resistant breast cancer model cells are inhibited by soybean glyceollin I through Eleanor non-coding RNA by Yamamoto, Tatsuro, Sakamoto, Chiyomi, Tachiwana, Hiroaki, Kumabe, Mitsuru, Matsui, Toshiro, Yamashita, Tadatoshi, Shinagawa, Masatoshi, Ochiai, Koji, Saitoh, Noriko, Nakao, Mitsuyoshi

“…Long-term estrogen deprivation (LTED) of an estrogen receptor (ER) α-positive breast cancer cell line recapitulates cancer cells that have acquired…”
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Metabolome analysis revealed that soybean-Aspergillus oryzae interaction induced dynamic metabolic and daidzein prenylation changes by Takahashi, Haruya, Ochiai, Koji, Sasaki, Kuni, Izumi, Atsushi, Shinyama, Yu, Mohri, Shinsuke, Nomura, Wataru, Jheng, Huei-Fen, Kawada, Teruo, Inoue, Kazuo, Goto, Tsuyoshi

“…Several isoflavonoids are well known for their ability to act as soybean phytoalexins. However, the overall effects of the soybean-Aspergillus oryzae…”
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Delayed tension gastrothorax caused necrosis of stomach and re-expansion pulmonary edema: a case report by Mochida, Yuki, Nishizawa, Ryohei, Ochiai, Koji, Inoue, Yoshitaka, Kaita, Yasuhiko, Yamaguchi, Yoshihiro

“…Background Traumatic tension gastrothorax is a rare and potentially fatal condition occurring in patients with congenital or acquired diaphragmatic defects…”
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Persistent Vegetative State after Diabetic Ketoacidosis Triggered by an Overdose of Psychotropic Agents by Kawashita, Takeshi, Nakajima, Mikio, Kaszynski, Richard H., Shirokawa, Masamitsu, Nakano, Tomotsugu, Ochiai, Koji, Inoue, Yoshitaka, Goto, Hideaki

“…A 28-year-old man with type 1 diabetes mellitus was admitted for shock and coma due to diabetic ketoacidosis. Despite aggressive treatment and management of…”
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Total Synthesis of the 7,10-Epimer of the Proposed Structure of Amphidinolide N, Part II: Synthesis of C17-C29 Subunit and Completion of the Synthesis by Ochiai, Koji, Kuppusamy, Sankar, Yasui, Yusuke, Harada, Kenji, Gupta, Nishant R., Takahashi, Yohei, Kubota, Takaaki, Kobayashi, Jun'ichi, Hayashi, Yujiro

“…The total synthesis of 7,10‐epimer of the proposed structure of amphidinolide N was accomplished. The requisite chiral C17–C29 subunit was assembled…”
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Total Synthesis of the 7,10-Epimer of the Proposed Structure of Amphidinolide N, Part I: Synthesis of the C1-C13 Subunit by Ochiai, Koji, Kuppusamy, Sankar, Yasui, Yusuke, Okano, Tsubasa, Matsumoto, Yasunobu, Gupta, Nishant R., Takahashi, Yohei, Kubota, Takaaki, Kobayashi, Jun'ichi, Hayashi, Yujiro

“…Amphidinolide N, the structure of which has been recently revised, is a 26‐membered macrolide featuring allyl epoxide and tetrahydropyran moieties with 13…”
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Ribosomal protein L5 facilitates rDNA-bundled condensate and nucleolar assembly by Matsumori, Haruka, Watanabe, Kenji, Tachiwana, Hiroaki, Fujita, Tomoko, Ito, Yuma, Tokunaga, Makio, Sakata-Sogawa, Kumiko, Osakada, Hiroko, Haraguchi, Tokuko, Awazu, Akinori, Ochiai, Hiroshi, Sakata, Yuka, Ochiai, Koji, Toki, Tsutomu, Ito, Etsuro, Goldberg, Ilya G, Tokunaga, Kazuaki, Nakao, Mitsuyoshi, Saitoh, Noriko

“…The nucleolus is the site of ribosome assembly and formed through liquid-liquid phase separation. Multiple ribosomal DNA (rDNA) arrays are bundled in the…”
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An Improved Method for Synthesis of 4,4-Dimethylpyrazolone and Application to Dihydropyridazinone Ring Formation by Ochiai, Koji, Kojima, Akihiko, Kohno, Yasushi

“…An improved method for 4,4-dimethylpyrazolone synthesis with t-butylcarbazate was described. The applicability of this method to dihydropyridazinone formation…”
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PS-BPB06-2: PIEZO2 EXPRESSION AND ITS ALTERATION BY MECHANICAL FORCES IN MOUSE MESANGIAL CELLS AND RENIN PRODUCING CELLS by Mochida, Yuki, Ochiai, Koji, Nagase, Miki

“…The kidney plays a central role in body fluid homeostasis. Cells in the glomeruli and juxtaglomerular apparatus sense mechanical forces and modulate glomerular…”
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Visualization Analysis of Glyceollin Production in Germinating Soybeans by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometric Imaging Technique by Abe, Chizumi, Zhang, Ye, Takao, Kazuhiro, Sasaki, Kuni, Ochiai, Koji, Matsui, Toshiro

“…Apart from the physiological functions of soybean phytoalexins, the production sites in soybeans remain unknown. In this study, the dynamic production of…”
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Carbohydrate Moiety of Time-Interval Measuring Enzyme Regulates Time Measurement through Its Interaction with Time-Holding Peptide PIN by Tani, Naoki, Kamada, Genji, Ochiai, Koji, Isobe, Minoru, Suwan, Sathorn, Kai, Hidenori

“…An ATPase called EA4 seems to measure time as a diapause-duration timer in the seasonal cycle of the silkworm, Bombyx mori. A peptide named PIN seems to…”
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Discovery of Novel Bicyclic Pyrazoles as Potent PIP5K1C Inhibitors by Ochiai, Koji, Seto, Shigeki, Yajima, Masanobu, Namie, Ryosuke, Hashimoto, Noriaki, Fujita, Motomichi, Yokoyama, Akinobu, Suezawa, Takahiro, Matsui, Hitomi, Tomizawa, Satoshi, Ishibashi, Yuji, Tanaka, Yuta, Yajima, Miho, Nagasawa, Michiaki, Ando, Naoki

“…Phosphatidylinositol-4,5-bisphosphate (PI­(4,5)­P2) is generated by phosphatidylinositol 4-phosphate 5-kinases (PIP5Ks) from phosphatidylinositol 4-phosphate…”
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