Search Results - "Ochi, Takafumi"
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1
c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
Published in Nature (09-04-2009)“…c-Myc links cancer to metabolism c-Myc is an oncogene involved in many forms of cancer. Proteomic analysis of human P-493 B lymphoma cells and PC3 prostate…”
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2
BubR1 Is Essential for Thio-Dimethylarsinic Acid-Induced Spindle Assembly Checkpoint and Mitotic Cell Death for Preventing the Accumulation of Abnormal Cells
Published in Biological & pharmaceutical bulletin (01-07-2019)“…Thio-dimethylarsinic acid (thio-DMA) was detected in human urine after exposure to inorganic arsenic and arsenosugars consumed by marine algae. Our previous…”
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3
Diphenylarsinic Acid Promotes Degradation of Glutaminase C by Mitochondrial Lon Protease
Published in The Journal of biological chemistry (25-05-2012)“…Glutaminase C (GAC), a splicing variant of the kidney-type glutaminase (KGA) gene, is a vital mitochondrial enzyme protein that catalyzes glutamine to…”
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4
Analysis of risk factors for anastomotic leakage after lower rectal Cancer resection, including drain type: a retrospective single-center study
Published in BMC gastroenterology (25-09-2020)“…We investigated the correlations between surgery-related factors and the incidence of anastomotic leakage after low anterior resection (LAR) for lower rectal…”
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5
New direct production of gluconic acid from polysaccharides using a bifunctional catalyst in hot water
Published in Catalysis communications (10-02-2011)“…Gluconic acid was produced from polysaccharides, such as starch and cellobiose, in water media at 393K under air by a one-pot process using a bifunctional…”
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6
Lactic acid production from glucose over activated hydrotalcites as solid base catalysts in water
Published in Catalysis communications (31-03-2008)“…The catalytic production of lactic acid from biomass derivatives over solid base catalysts was studied for future sustainable societies. The activated…”
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7
Thio-dimethylarsinate is a common metabolite in urine samples from arsenic-exposed women in Bangladesh
Published in Toxicology and applied pharmacology (01-08-2007)“…Over the last 6 years, much work on arsenic species in urine samples has been directed toward the determination of the reduced dimethylated arsenic species,…”
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Journal Article Conference Proceeding -
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Phosphorylation of histone H3 at serine 10 has an essential role in arsenite-induced expression of FOS, EGR1 and IL8 mRNA in cultured human cell lines
Published in Journal of applied toxicology (01-08-2013)“…ABSTRACT Trivalent inorganic arsenite [iAs(III)] is known to alter the expression of a number of genes associated with transcription and cell proliferation,…”
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Cytotoxic, genotoxic and cell-cycle disruptive effects of thio-dimethylarsinate in cultured human cells and the role of glutathione
Published in Toxicology and applied pharmacology (01-04-2008)“…Thio-dimethylarsinate (thio-DMA), a recently discovered urine metabolite in humans, was investigated for its cytotoxic, genotoxic and cell-cycle disruptive…”
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Diphenylarsinic acid produces behavioral effects in mice relevant to symptoms observed in citizens who ingested polluted well water
Published in Neurotoxicology and teratology (01-01-2012)“…Abstract Citizens in an area of Kamisu City, Ibaraki, Japan had exhibited unusual health problems, and pollution of well water by diphenylarsinic acid (DPAA)…”
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11
Urine analysis of patients exposed to phenylarsenic compounds via accidental pollution
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15-05-2008)“…New methods involving high-performance liquid chromatography/inductively coupled plasma mass spectrometry were examined for the determination of phenylarsenic…”
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12
Trivalent dimethylarsenic compound induces histone H3 phosphorylation and abnormal localization of Aurora B kinase in HepG2 cells
Published in Toxicology and applied pharmacology (15-12-2009)“…Trivalent dimethylarsinous acid [DMA(III)] has been shown to induce mitotic abnormalities, such as centrosome abnormality, multipolar spindles, multipolar…”
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13
Down-regulation of glutaminase C in human hepatocarcinoma cell by diphenylarsinic acid, a degradation product of chemical warfare agents
Published in Toxicology and applied pharmacology (01-05-2007)“…In a poisonous incident in Kamisu, Japan, it is understood that diphenylarsinic acid (DPAA) was a critical contaminant of ground water. Most patients showed…”
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14
In vitro cytotoxic and genotoxic effects of diphenylarsinic acid, a degradation product of chemical warfare agents
Published in Toxicology and applied pharmacology (01-10-2004)“…Diphenylarsinic acid [DPAs(V)], a degradation product of diphenylcyanoarsine or diphenylchloroarsine, both of which were developed as chemical warfare agents,…”
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15
Structure-effect relationship in the down-regulation of glutaminase in cultured human cells by phenylarsenic compounds
Published in Toxicology (Amsterdam) (28-04-2009)“…Abstract Diphenylarsinic acid [DPAA(V)] was detected in ground water used as drinking water after a poisonous incident in Kamisu, Japan. An approach to define…”
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16
Glutathione plays a role in regulating the formation of toxic reactive intermediates from diphenylarsinic acid
Published in Toxicology (Amsterdam) (15-08-2006)“…The role of glutathione (GSH) in the cytotoxicity of diphenylarsinic acid [DPAA(V)], which was detected in drinking well water after a poisoning incident in…”
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ジメチルヒ素処理哺乳類細胞における染色体異数性,中心体異常,多極紡錘体,多極分裂の誘発
Published in YAKUGAKU ZASSHI (01-06-2016)“…環境中のヒ素はそれぞれ三価と五価の無機ヒ素化合物として存在する. また種々のメチル化代謝物としても存在する. 生態系において, 無機ヒ素は嫌気性菌によって還元され, またメチル化され, メチルアルソン酸methylarsonic acid[MAA(V)]及びジメチルアルシン酸dimethylarsinic…”
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The role of glutathione on the cytotoxic effects and cellular uptake of diphenylarsinic acid, a degradation product of chemical warfare agents
Published in Archives of toxicology (01-08-2006)“…The mechanism underlying enhancement of the cytotoxic effects of diphenylarsinic acid (DPAA) by sulfhydryl (SH) compounds, such as glutathione (GSH) and…”
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Induction of Aneuploidy, Centrosome Abnormality, Multipolar Spindle, and Multipolar Division in Cultured Mammalian Cells Exposed to an Arsenic Metabolite, Dimethylarsinate
Published in YAKUGAKU ZASSHI (01-06-2016)“…Toxicological studies of arsenic compounds were conducted in cultured mammalian cells to investigate the effects of glutathione (GSH) depletion…”
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Hydrolysis of Cellulose Selectively into Glucose Over Sulfonated Activated-Carbon Catalyst Under Hydrothermal Conditions
Published in Topics in catalysis (01-06-2009)“…A sulfonated activated-carbon (AC-SO 3 H) catalyst selectively hydrolyzes cellulose with β-1,4-glycosidic bonds into glucose in the catalytic hydrothermal…”
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