Siblings With Cystic Leukoencephalopathy and Megalencephaly

Siblings With Cystic Leukoencephalopathy and Megalencephaly

Cystic leukoencephalopathy with megalencephaly is a newly described entity with mild clinical involvement. Patients suffer from developmental problems and seizures in childhood. Progression is gradual into adulthood. Typical magnetic resonance imaging findings include subcortical cysts and diffuse l...

Full description

Saved in:
Bibliographic Details
Published in:Journal of child neurology Vol. 15; no. 10; pp. 690 - 693
Main Authors: Yalçinkaya, Cengiz, Çomu, Sinan, Koçer, Naci, Yüksel, Adnan, Gündüz, Erem, Demirbilek, Veysi, Ocal, Ayla
Format: Journal Article
Language:English
Published: Thousand Oaks, CA Sage Publications 01-10-2000
SAGE PUBLICATIONS, INC
Subjects:
Adults
Attendance
Brain - abnormalities
Brain Diseases - complications
Brain Diseases - diagnosis
Brain Diseases - genetics
Child
Consanguinity
Cysts - complications
Cysts - diagnosis
Cysts - genetics
Dementia, Vascular - complications
Dementia, Vascular - diagnosis
Dementia, Vascular - genetics
Developmental Delays
Diagnosis, Differential
Etiology
Family (Sociological Unit)
Genetic Disorders
Humans
Magnetic Resonance Imaging
Male
Motor Development
Patients
Pedigree
Pregnancy
Seizures
Severity (of Disability)
Siblings
Trauma
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Cystic leukoencephalopathy with megalencephaly is a newly described entity with mild clinical involvement. Patients suffer from developmental problems and seizures in childhood. Progression is gradual into adulthood. Typical magnetic resonance imaging findings include subcortical cysts and diffuse leukoencephalopathy. The etiology is unknown with possibly autosomal-recessive inheritance. We present two pairs of siblings with this disease and emphasize the characteristic and variable patterns even within the same family. (J Child Neurol 2000;15:690-693).
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ObjectType-Case Study-2
ObjectType-Feature-4
ObjectType-Report-1
ObjectType-Article-3
ISSN:0883-0738
1708-8283
DOI:10.1177/088307380001501010