Search Results - "Ocak, Meltem"

Application of response surface methodology and quality by design to [68Ga]Ga-PSMA-11 preparation by Pehlivanoglu, Huseyin, Ocak, Meltem, Caglar-Andac, Sena

“…In this study, the optimum conditions for the synthesis of [ 68 Ga]Ga-PSMA-11 were determined for the first time using the Quality by Design (QbD). The…”
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EANM guideline on the validation of analytical methods for radiopharmaceuticals by Gillings, Nic, Todde, Sergio, Behe, Martin, Decristoforo, Clemens, Elsinga, Philip, Ferrari, Valentina, Hjelstuen, Olaug, Peitl, Petra Kolenc, Koziorowski, Jacek, Laverman, Peter, Mindt, Thomas L., Ocak, Meltem, Patt, Marianne

“…Background To fulfil good manufacturing requirements, analytical methods for the analysis of pharmaceuticals for human and vetinary use must be validated. The…”
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Guideline on current good radiopharmacy practice (cGRPP) for the small-scale preparation of radiopharmaceuticals by Gillings, Nic, Hjelstuen, Olaug, Ballinger, Jim, Behe, Martin, Decristoforo, Clemens, Elsinga, Philip, Ferrari, Valentina, Peitl, Petra Kolenc, Koziorowski, Jacek, Laverman, Peter, Mindt, Thomas L., Neels, Oliver, Ocak, Meltem, Patt, Marianne, Todde, Sergio

“…This guideline on current good radiopharmacy practice (cGRPP) for small-scale preparation of radiopharmaceuticals represents the view of the Radiopharmacy…”
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Evaluation of F-18 DOPA PET/CT in the detection of recurrent or metastatic medullary thyroid carcinoma: comparison with GA-68 DOTA-TATE PET/CT by Asa, Sertac, Sonmezoglu, Kerim, Uslu-Besli, Lebriz, Sahin, Onur Erdem, Karayel, Emre, Pehlivanoglu, Huseyin, Sager, Sait, Kabasakal, Levent, Ocak, Meltem, Sayman, Haluk B.

“…Objective PET imaging with F-18 DOPA (FDOPA) and Ga-68 DOTATATE (TATE) shows the most promising results to detect medullary thyroid cancer (MTC) recurrence. We…”
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[68Ga]DOTA-FAPI-04 PET/CT imaging in a case of a signet ring cell carcinoma of stomach by Alan-Selçuk, Nalan, Ergen, Selçuk, Demirci, Emre, Ocak, Meltem, Kabasakal, Levent

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Performance of F-18 Fluorocholine PET/CT for Detection of Hyperfunctioning Parathyroid Tissue in Patients with Elevated Parathyroid Hormone Levels and Negative or Discrepant Results in conventional Imaging by Uslu-Beşli, Lebriz, Sonmezoglu, Kerim, Teksoz, Serkan, Akgun, Elife, Karayel, Emre, Pehlivanoglu, Huseyin, Khosroshahi, Baresh Razavi, Ocak, Meltem, Kabasakal, Levent, Sager, Sait, Bukey, Yusuf

“…Our aim was to assess the diagnostic performance of F-18 fluorocholine (FCH) positron emission tomography/computed tomography (PET/CT) in detecting…”
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Folate Receptor-Targeted Multimodality Imaging of Ovarian Cancer in a Novel Syngeneic Mouse Model by Ocak, Meltem, Gillman, Andrea G, Bresee, Jamee, Zhang, Lixin, Vlad, Anda M, Müller, Cristina, Schibli, Roger, Edwards, W. Barry, Anderson, Carolyn J, Gach, H. Michael

“…A new transplantable ovarian tumor model is presented using a novel folate receptor (FR) positive, murine ovarian cancer cell line that emulates the human…”
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Preclinical Evaluation of F-ML-10 to Determine Timing of Apoptotic Response to Chemotherapy in Solid Tumors by Emre Demirci MD, Rafay Ahmed MD, Meltem Ocak PhD, Joseph Latoche BS, April Radelet BS, Nicole DeBlasio BS, N. Scott Mason PhD, Carolyn J. Anderson PhD, James M. Mountz MD, PhD

“…Purpose: We investigated 2-(5-fluoro-pentyl)-2-methyl-malonic acid ( 18 F-ML-10) positron emission tomography (PET) imaging of apoptosis posttherapy to…”
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Lu-177-PSMA-617 Prostate-Specific Membrane Antigen Inhibitor Therapy in Patients with Castration-Resistant Prostate Cancer: Stability, Bio-distribution and Dosimetry by Kabasakal, Levent, Toklu, Türkay, Yeyin, Nami, Demirci, Emre, Abuqbeitah, Mohammad, Ocak, Meltem, Aygün, Aslan, Karayel, Emre, Pehlivanoğlu, Hüseyin, Alan Selçuk, Nalan

“…The aim of the study was to estimate the radiation-absorbed doses and to study the in vivo and in vitro stability as well as pharmacokinetic characteristics of…”
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Radiolabelling of peptides for PET, SPECT and therapeutic applications using a fully automated disposable cassette system by Petrik, Milos, Knetsch, Peter A, Knopp, Roger, Imperato, Giovanni, Ocak, Meltem, von Guggenberg, Elisabeth, Haubner, Roland, Silbernagl, Roland, Decristoforo, Clemens

“…OBJECTIVESRadiolabelled somatostatin analogues have found wide clinical use in nuclear medicine for both diagnostic and therapeutic applications. Here, we…”
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Pre-therapeutic dosimetry of normal organs and tissues of (177)Lu-PSMA-617 prostate-specific membrane antigen (PSMA) inhibitor in patients with castration-resistant prostate cancer by Kabasakal, Levent, AbuQbeitah, Mohammad, Aygün, Aslan, Yeyin, Nami, Ocak, Meltem, Demirci, Emre, Toklu, Turkay

“…(177)Lu-617-prostate-specific membrane antigen (PSMA) ligand seems to be a promising tracer for radionuclide therapy of progressive prostate cancer. However,…”
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(68)Ga-PSMA PET/CT imaging of metastatic clear cell renal cell carcinoma by Demirci, Emre, Ocak, Meltem, Kabasakal, Levent, Decristoforo, Clemens, Talat, Zübeyir, Halaç, Metin, Kanmaz, Bedii

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Post-therapy imaging of 225Ac-DOTATATE treatment in a patient with recurrent neuroendocrine tumor by Ocak, Meltem, Toklu, Türkay, Demirci, Emre, Selçuk, Nalan, Kabasakal, Levent

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Comparison of 68Ga-DOTATATE and 68Ga-DOTANOC PET/CT imaging in the same patient group with neuroendocrine tumours by Kabasakal, Levent, Demirci, Emre, Ocak, Meltem, Decristoforo, Clemens, Araman, Ahmet, Ozsoy, Yıldız, Uslu, Ilhami, Kanmaz, Bedii

“…Purpose Recent studies have suggested that positron emission tomography (PET) imaging with 68 Ga-labelled DOTA-somatostatin analogues (SST) like octreotide and…”
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Clinical Experience with [ 225 Ac]Ac-PSMA Treatment in Patients with [ 177 Lu]Lu-PSMA–Refractory Metastatic Castration-Resistant Prostate Cancer by Alan-Selcuk, Nalan, Beydagi, Gamze, Demirci, Emre, Ocak, Meltem, Celik, Serkan, Oven, Bala B., Toklu, Turkay, Karaaslan, Ipek, Akcay, Kaan, Sonmez, Omer, Kabasakal, Levent

“…For patients with advanced-stage metastatic castration-resistant prostate cancer (mCRPC) who do not respond to [177Lu]Lu-PSMA therapy, there are limited…”
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Development and validation of a UV-Radio-HPLC method to assess chemical and radiochemical purity of [68Ga] Ga-PSMA-11 by Pehli̇vanoglu, Huseyin, Ocak, Meltem, Caglar-Andac, Sena

“…[68Ga]Ga-PSMA-11, a urea-based peptidomimetic, has been widely used in recent years for PET imaging of patients with prostate cancer. Since it has short…”
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Interobserver and intraobserver agreement on prostate-specific membrane antigen PET/CT images according to the miTNM and PSMA-RADS criteria by Demirci, Emre, Akyel, Reşit, Caner, Biray, Alan-Selçuk, Nalan, Güven-Meşe, Şermin, Ocak, Meltem, Kabasakal, Levent

“…AIMIn this study, we aimed to measure interobserver and intraobserver agreement in Ga-68–prostate-specific membrane antigen (PSMA) PET/computed tomography (CT)…”
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EANM guideline on quality risk management for radiopharmaceuticals by Gillings, Nic, Hjelstuen, Olaug, Behe, Martin, Decristoforo, Clemens, Elsinga, Philip H., Ferrari, Valentina, Kiss, Oliver C., Kolenc, Petra, Koziorowski, Jacek, Laverman, Peter, Mindt, Thomas L., Ocak, Meltem, Patt, Marianne, Todde, Sergio, Walte, Almut

“…This document is intended as a supplement to the EANM “Guidelines on current Good Radiopharmacy Practice (cGRPP)” issued by the Radiopharmacy Committee of the…”
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The role of PSMA PET/CT imaging in restaging of prostate cancer patients with low prostate-specific antigen levels by Kabasakal, Levent, Demirci, Emre, Nematyazar, Jamal, Akyel, Reşit, Razavi, Baresh, Ocak, Meltem, Aygun, Aslan, Obek, Can, Kural, Ali R

“…INTRODUCTIONProstate-specific membrane antigen (PSMA) is increasingly being recognized as a novel target for the PET imaging of prostate cancer (PCa) and…”
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Post-therapy imaging of 225 Ac-DOTATATE treatment in a patient with recurrent neuroendocrine tumor by Ocak, Meltem, Toklu, Türkay, Demirci, Emre, Selçuk, Nalan, Kabasakal, Levent

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