Search Results - "Obrochta, A."

The impact of patient travel time on disparities in treatment for early stage lung cancer in California by Obrochta, Chelsea A, Parada, Humberto, Murphy, James D, Nara, Atsushi, Trinidad, Dennis, Araneta, Maria Rosario (Happy), Thompson, Caroline A

“…Background Travel time to treatment facilities may impede the receipt of guideline-concordant treatment (GCT) among patients diagnosed with early-stage…”
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Accurate and safe mediastinal restaging by combined endobronchial and endoscopic ultrasound-guided needle aspiration performed by single ultrasound bronchoscope by Szlubowski, Artur, Zieliński, Marcin, Soja, Jerzy, Filarecka, Anna, Orzechowski, Stanisław, Pankowski, Juliusz, Obrochta, Anna, Jakubiak, Magdalena, Węgrzyn, Joanna, Ćmiel, Adam

“…OBJECTIVES The aim of this prospective trial was to assess the diagnostic utility of combined endobronchial (EBUS) and endoscopic (EUS) ultrasound-guided…”
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Psychological distress in pregnancy and postpartum by Obrochta, Chelsea A., Chambers, Christina, Bandoli, Gretchen

“…Depression, stress, and anxiety, termed ‘psychological distress,’ are common in pregnancy and postpartum periods. However, it is unclear whether prenatal…”
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A gene drive is a gene drive: the debate over lumping or splitting definitions by James, Stephanie L., O’Brochta, David A., Randazzo, Filippo, Akbari, Omar S.

“…We address a controversy over use of the term “gene drive” to include both natural and synthetic genetic elements that promote their own transmission within a…”
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Disentangling Racial, Ethnic, and Socioeconomic Disparities in Treatment for Colorectal Cancer by Obrochta, Chelsea A, Murphy, James D, Tsou, Ming-Hsiang, Thompson, Caroline A

“…Colorectal cancer is curable if diagnosed early and treated properly. Black and Hispanic patients with colorectal cancer are more likely to experience…”
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Organization of olfactory centres in the malaria mosquito Anopheles gambiae by Riabinina, Olena, Task, Darya, Marr, Elizabeth, Lin, Chun-Chieh, Alford, Robert, O'Brochta, David A., Potter, Christopher J.

“…Mosquitoes are vectors for multiple infectious human diseases and use a variety of sensory cues (olfactory, temperature, humidity and visual) to locate a human…”
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Advanced technologies for genetically manipulating the silkworm Bombyx mori, a model Lepidopteran insect by Xu, Hanfu, O'Brochta, David A.

“…Genetic technologies based on transposon-mediated transgenesis along with several recently developed genome-editing technologies have become the preferred…”
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Post-integration silencing of piggyBac transposable elements in Aedes aegypti by Palavesam, Azhahianambi, Esnault, Caroline, O'Brochta, David A

“…The piggyBac transposon, originating in the genome of the Lepidoptera Trichoplusia ni, has a broad host range, making it useful for the development of a number…”
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Is Saglin a mosquito salivary gland receptor for Plasmodium falciparum? by O'Brochta, David A, Alford, Robert, Harrell, Robert, Aluvihare, Channa, Eappen, Abraham G, Li, Tao, Chakravarty, Sumana, Sim, B Kim Lee, Hoffman, Stephen L, Billingsley, Peter F

“…Saglin, a 100 kDa protein composed of two 50 kDa homodimers, is present in the salivary glands of Anopheles gambiae and has been considered an essential…”
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Leveraging eco-evolutionary models for gene drive risk assessment by Combs, Matthew A., Golnar, Andrew J., Overcash, Justin M., Lloyd, Alun L., Hayes, Keith R., O’Brochta, David A., Pepin, Kim M.

“…As development of gene drive systems accelerates and diversifies, predicting outcomes for target populations and the potential for human and environmental…”
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Applications of genome editing in insects by Reid, William, O’Brochta, David A

“…•Tunable DNA binding protein systems provide platforms for gene editing and more.•Modifying/editing insect genotypes is not limited to ‘model’…”
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Transient knockdown of Anopheles stephensi LRIM1 using RNAi increases Plasmodium falciparum sporozoite salivary gland infections by Billingsley, Peter F, George, Kasim I, Eappen, Abraham G, Harrell, 2nd, Robert A, Alford, Robert, Li, Tao, Chakravarty, Sumana, Sim, B Kim Lee, Hoffman, Stephen L, O'Brochta, David A

“…Plasmodium falciparum (Pf) sporozoites (PfSPZ) can be administered as a highly protective vaccine conferring the highest protection seen to date. Sanaria®…”
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An ex vivo system for investigation of Plasmodium berghei invasion of the salivary gland of Anopheles stephensi mosquitoes by Hussien, Mai I., Soliman, Belal A., Tewfick, Maha K., O'Brochta, David A.

“…Plasmodium sporozoites associated with the midgut and in the hemolymph of mosquitoes differ from sporozoites in the secretory cavities and ducts of the…”
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An Anopheles stephensi Promoter-Trap: Augmenting Genome Annotation and Functional Genomics by Reid, William, Pilitt, Kristina, Alford, Robert, Cervantes-Medina, Adriana, Yu, Hao, Aluvihare, Channa, Harrell, Rob, O'Brochta, David A

“…The piggyBac transposon was modified to generate gene trap constructs, which were then incorporated into the genome of the Asian malaria vector, and…”
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Phylogenetic and functional characterization of the hAT transposon superfamily by Arensburger, Peter, Hice, Robert H, Zhou, Liqin, Smith, Ryan C, Tom, Ariane C, Wright, Jennifer A, Knapp, Joshua, O'Brochta, David A, Craig, Nancy L, Atkinson, Peter W

“…Transposons are found in virtually all organisms and play fundamental roles in genome evolution. They can also acquire new functions in the host organism and…”
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Cre/lox-Recombinase-Mediated Cassette Exchange for Reversible Site-Specific Genomic Targeting of the Disease Vector, Aedes aegypti by Häcker, Irina, Harrell II, Robert A., Eichner, Gerrit, Pilitt, Kristina L., O’Brochta, David A., Handler, Alfred M., Schetelig, Marc F.

“…Site-specific genome modification (SSM) is an important tool for mosquito functional genomics and comparative gene expression studies, which contribute to a…”
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A Cross-Sectional Survey of Biosafety Professionals Regarding Genetically Modified Insects by O’Brochta, David A., Tonui, Willy K., Dass, Brinda, James, Stephanie

“…Background: Genetic technologies such as gene editing and gene drive create challenges for existing frameworks used to assess risk and make regulatory…”
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Gal4-based enhancer-trapping in the malaria mosquito Anopheles stephensi by O'Brochta, David A, Pilitt, Kristina L, Harrell, 2nd, Robert A, Aluvihare, Channa, Alford, Robert T

“…Transposon-based forward and reverse genetic technologies will contribute greatly to ongoing efforts to study mosquito functional genomics. A piggyBac…”
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piggyBac transposon remobilization and enhancer detection in Anopheles mosquitoes by O'Brochta, David A, Alford, Robert T, Pilitt, Kristina L, Aluvihare, Channa U, Harrell, Robert A., II

“…Technical advances in mosquito biology are enabling the development of new approaches to vector control. Absent are powerful forward-genetics technologies,…”
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Assessing fitness costs for transgenic Aedes aegypti expressing the GFP marker and transposase genes by Irvin, N, Hoddle, M.S, O'Brochta, D.A, Carey, B, Atkinson, P.W

“…The development of transgenic mosquitoes that are refractory to the transmission of human diseases such as malaria, dengue, and yellow fever has received much…”
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