Search Results - "Obreztchikova, Maria N"

IKr contributes to the altered ventricular repolarization that determines long-term cardiac memory by OBREZTCHIKOVA, Maria N, PATBERG, Komelis W, ROSEN, Michael R, PLOTNIKOV, Alexei N, OZGEN, Nazira, SHLAPAKOVA, Irina N, RYBIN, Andrew V, SOSUNOV, Eugene A, DANILO, Peter, ANYUKHOVSKY, Evgeny P, ROBINSON, Richard B

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Developmental changes in IKr and IKs contribute to age-related expression of dofetilide effects on repolarization and proarrhythmia by OBREZTCHIKOVA, Maria N, SOSUNOV, Eugene A, PLOTNIKOV, Alexei, ANYUKHOVSKY, Evgeny P, GAINULLIN, Ravil Z, DANILO, Peter JR, YEOM, Zi-Ho, ROBINSON, Richard B, ROSEN, Michael R

“…Clinical and experimental studies suggest that immature hearts are as or more sensitive than adult hearts to adverse effects of I(Kr) blocking drugs. We…”
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The cAMP response element binding protein modulates expression of the transient outward current : Implications for cardiac memory by PATBERG, Kornelis W, OBREZTCHIKOVA, Maria N, SHIAPAKOVA, Iryna, DANILO, Peter JR, YANG, Jay, ROSEN, Michael R, GIARDINA, Sarah F, SYMES, Aviva J, PLOTNIKOV, Alexei N, JIHONG QU, CHANDRA, Parag, MCKINNON, David, LIOU, Shian R, RYBIN, Andrew V

“…Long-term cardiac memory (LTCM), expressed as a specific pattern of T-wave change on ECG, is associated with 1) reduced transient outward potassium current…”
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Developmental evolution of the delayed rectifier current IKs in canine heart appears dependent on the beta subunit minK by Krishnamurthy, Ganga, Patberg, Kornelis W, Obreztchikova, Maria N, Rybin, Andrew V, Rosen, Michael R

“…We tested the hypothesis that the developmental changes occurring in I(Kr) and I(Ks) can be explained by changes in the expression of ERG encoding I(Kr), and…”
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Mechanisms of α-adrenergic potentiation of ventricular arrhythmias in dogs with inherited arrhythmic sudden death by SOSUNOV, Eugene A, OBREZTCHIKOVA, Maria N, ANYUKHOVSKY, Evgeny P, MOÏSE, N. Sydney, DANILO, Peter JR, ROBINSON, Richard B, ROSEN, Michael R

“…In German shepherd dogs having inherited arrhythmias and sudden death, pause-dependent arrhythmias are triggered by early afterdepolarizations (EADs)…”
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Heterogeneous ventricular repolarization provides a substrate for arrhythmias in a German shepherd model of spontaneous arrhythmic death by OBREZTCHIKOVA, Maria N, SOSUNOV, Eugene A, ANYUKHOVSKY, Evgeny P, MOÏSE, N. Sydney, ROBINSON, Richard B, ROSEN, Michael R

“…German shepherd dogs with inherited arrhythmias and sudden death appear to be a model for catecholamine-dependent ventricular tachycardias in human subjects…”
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Electrophysiological studies of ion channels and therapeutic potential with adenovirus-mediated gene transfer by Qu, Jihong, Pham, Thai V, Obreztchikova, Maria N

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I(Kr) contributes to the altered ventricular repolarization that determines long-term cardiac memory by Obreztchikova, Maria N, Patberg, Kornelis W, Plotnikov, Alexei N, Ozgen, Nazira, Shlapakova, Irina N, Rybin, Andrew V, Sosunov, Eugene A, Danilo, Jr, Peter, Anyukhovsky, Evgeny P, Robinson, Richard B, Rosen, Michael R

“…Cardiac memory (CM) is characterized by an altered T-wave morphology, which reflects altered repolarization gradients. We hypothesized that the delayed…”
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