Search Results - "Obradovic, Milan"
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1
Glucocorticoids promote breast cancer metastasis
Published in Nature (London) (01-03-2019)“…Diversity within or between tumours and metastases (known as intra-patient tumour heterogeneity) that develops during disease progression is a serious hurdle…”
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2
Single-cell Analysis Reveals Inter- and Intratumour Heterogeneity in Metastatic Breast Cancer
Published in Journal of mammary gland biology and neoplasia (01-12-2023)“…Metastasis is the leading cause of cancer-related deaths of breast cancer patients. Some cancer cells in a tumour go through successive steps, referred to as…”
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3
Leptin and Obesity: Role and Clinical Implication
Published in Frontiers in endocrinology (Lausanne) (18-05-2021)“…The peptide hormone leptin regulates food intake, body mass, and reproductive function and plays a role in fetal growth, proinflammatory immune responses,…”
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4
Review of the speculative role of co-infections in Streptococcus suis-associated diseases in pigs
Published in Veterinary research (Paris) (20-03-2021)“…Streptococcus suis is one of the most important bacterial swine pathogens affecting post-weaned piglets, causing mainly meningitis, arthritis and sudden death…”
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5
Tryptophan Metabolism in Atherosclerosis and Diabetes
Published in Current medicinal chemistry (2022)“…The essential amino acid tryptophan (Trp) undergoes catabolism through several pathways, producing biologically active metabolites that significantly impact…”
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Link between Metabolic Syndrome and Insulin Resistance
Published in Current vascular pharmacology (01-01-2017)“…Metabolic syndrome (MetS) is a leading public health and clinical challenge worldwide. MetS represents a group of interrelated risk factors that predict…”
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7
Experimental evaluation of protection and immunogenicity of Streptococcus suis bacterin-based vaccines formulated with different commercial adjuvants in weaned piglets
Published in Veterinary research (Paris) (19-10-2021)“…Abstract Streptococcus suis is an important swine pathogen responsible for economic losses to the swine industry worldwide. There is no effective commercial…”
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The Role of miRNAs in Metabolic Diseases
Published in Current medicinal chemistry (01-01-2023)“…Metabolic diseases such as obesity, diabetes, dyslipidemia, and insulin resistance are characterized by glucose and lipid metabolism alterations and represent…”
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Role of C-Reactive Protein in Diabetic Inflammation
Published in Mediators of inflammation (2022)“…Even though type 2 diabetes mellitus (T2DM) represents a worldwide chronic health issue that affects about 462 million people, specific underlying determinants…”
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10
Glutathione “Redox Homeostasis” and Its Relation to Cardiovascular Disease
Published in Oxidative medicine and cellular longevity (01-01-2019)“…More people die from cardiovascular diseases (CVD) than from any other cause. Cardiovascular complications are thought to arise from enhanced levels of free…”
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11
Immune response and protection against Lawsonia intracellularis infections in pigs
Published in Veterinary immunology and immunopathology (01-01-2020)“…Lawsonia intracellularis are Gram-negative, obligate intracellular bacteria that cause proliferative enteropathy (PE), an economically important disease for…”
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12
Evidence for a common mucosal immune system in the pig
Published in Molecular immunology (01-07-2015)“…•There is evidence that the common mucosal immune system exists in pigs.•Vaccination at an easily accessible mucosal site may assist in providing protection at…”
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13
Immune response induced by a Streptococcus suis multi-serotype autogenous vaccine used in sows to protect post-weaned piglets
Published in Veterinary research (Paris) (07-05-2024)“…Streptococcus suis is a bacterial pathogen that causes important economic losses to the swine industry worldwide. Since there are no current commercial…”
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14
Endothelial Dysfunction in Dyslipidaemia: Molecular Mechanisms and Clinical Implications
Published in Current medicinal chemistry (01-01-2020)“…The endothelium consists of a monolayer of Endothelial Cells (ECs) which form the inner cellular lining of veins, arteries, capillaries and lymphatic vessels…”
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15
Drug Delivery Systems for Diabetes Treatment
Published in Current pharmaceutical design (01-01-2019)“…Insulin is essential for the treatment of Type 1 diabetes mellitus (T1DM) and is necessary in numerous cases of Type 2 diabetes mellitus (T2DM). Prolonged…”
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16
PCSK9 inhibition - a novel mechanism to treat lipid disorders?
Published in Current pharmaceutical design (2013)“…Plasma low-density lipoprotein cholesterol (LDL-C) is one of the biomarkers of cardiovascular disease (CVD) risk. LDL is cleared from the circulation…”
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17
Regulation of nitric oxide production in hypothyroidism
Published in Biomedicine & pharmacotherapy (01-04-2020)“…Hypothyroidism is a common endocrine disorder that predominantly occurs in females. It is associated with an increased risk of cardiovascular diseases (CVD),…”
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18
The Na + /K + -ATPase: A potential therapeutic target in cardiometabolic diseases
Published in Frontiers in endocrinology (Lausanne) (28-02-2023)“…Cardiometabolic diseases (CMD) are a direct consequence of modern living and contribute to the development of multisystem diseases such as cardiovascular…”
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Insulin-like growth factor-1 reduces cardiac autosis through decreasing AMPK/FOXO1 signaling and Na + /K + -ATPase-Beclin-1 interaction
Published in Archives of medical science (01-01-2024)“…Insulin-like growth factor-1 (IGF-1) promotes survival and inhibits cardiac autophagy disruption. Male Wistar rats were treated with IGF-1 (50 µg/kg), and 24 h…”
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Nitric oxide, thyroglobulin, and calcitonin: unraveling the nature of thyroid nodules
Published in Frontiers in endocrinology (Lausanne) (28-09-2023)“…Background Thyroid nodules (TN) are localized morphological changes in the thyroid gland and can be benign or malignant. Objective The present study…”
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