Search Results - "Obniska, J"

Synthesis, anticonvulsant activity and 5-HT1A, 5-HT2A receptor affinity of new N-[(4-arylpiperazin-1-yl)-alkyl] derivatives of 2-azaspiro[4.4]nonane and [4.5]decane-1,3-dione by OBNISKA, J, KOLACZKOWSKI, M, BOJARSKI, A. J, DUSZYNSKA, B

“…The synthesis, physicochemical and pharmacological properties of new N-[(4-arylpiperazin-1-yl)-alkyl]-2-azaspiro[4.4]nonane- (8a-c, 10a-d) and…”
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Preliminary study on application of impregnated synthetic peptide TLC stationary phases for the pre-screening of 5-HT1A ligands by Zajdel, PaweŁ, Bojarski, Andrzej J., Byrtus, Hanna, ChŁoń-Rzepa, Grażyna, Obniska, Jolanta, Chevallet, Pierre, Martinez, Jean, PawŁowski, Maciej

“…Chromatographic parameters (ΔRf), defined as a difference in the migration of tested compound on the control and peptide impregnated silica gel TLC plates,…”
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Antiallodynic and antihyperalgesic activity of new 3,3-diphenyl-propionamides with anticonvulsant activity in models of pain in mice by Rapacz, Anna, Obniska, Jolanta, Koczurkiewicz, Paulina, Wójcik-Pszczoła, Katarzyna, Siwek, Agata, Gryboś, Anna, Rybka, Sabina, Karcz, Aleksandra, Pękala, Elżbieta, Filipek, Barbara

“…Anticonvulsant drugs are used to treat a wide range of non-epileptic conditions, including chronic pain. The aim of the present experiments was to examine…”
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Analgesic-like activity of piperazine derivatives of 3,3-disubstituted pyrrolidine-2,5-diones in mice by Jastrzebska-Wiesek, M, Fabian, M, Partyka, A, Obniska, J, Wesolowska, A

“…Serotonin (5-HT) and its receptors play a multifaceted role in pain modulation. Among the many subtypes of 5-HT receptors potentially contributing to…”
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CO…HC interactions as packing motifs in the crystals: Part 4. Intermolecular interactions in the structures of N-[(4-arylpiperazin-1-yl)-alkyl]2-azaspiro[4.4]nonane and [4.5]decane-1,3-dione derivatives by Karolak-Wojciechowska, J., Mrozek, A., Dzierżawska-Majewska, A., Obniska, J.

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CO…HC interactions as packing motifs in crystals: Part 3. Impact of chloro-substituents on the structures of N-(chloro)-benzyl-3-spirocycloalkylopyrrolidine-2,5-diones by Karolak-Wojciechowska, J., Dzierżwska-Majewska, A., Obniska, J.

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C O…H C interactions as packing motifs in crystals: Part 3. Impact of chloro-substituents on the structures of N-(chloro)-benzyl-3-spirocycloalkylopyrrolidine-2,5-diones by Karolak-Wojciechowska, J., Dzierżwska-Majewska, A., Obniska, J.

“…In continuation of the studies on weak H-bond formation in N-benzyl- and N-aminophenyl-succinimides, a series of six…”
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C O…H C interactions as packing motifs in the crystals: Part 4. Intermolecular interactions in the structures of N-[(4-arylpiperazin-1-yl)-alkyl]2-azaspiro[4.4]nonane and [4.5]decane-1,3-dione derivatives by Karolak-Wojciechowska, J., Mrozek, A., Dzierżawska-Majewska, A., Obniska, J.

“…In continuation of the studies on weak H-bond formation in N-substituted-spiro-succinimides, the crystal structures of three derivatives from the series of…”
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Synthesis and pharmacological investigation of new N-dimethylpyridyl and N-chloropyridyl substituted arylsuccinimides by Zejc, A, Obniska, J, Jakowicz, I

“…In the reaction of alpha-phenyl-, alpha-p-chlorophenyl-, alpha-m-chlorophenyl-, alpha-p-bromophenyl and alpha-m-bromophenyl succinic acids with various…”
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Structures of three N-pyridyl-2-phenylsuccinimides and structural evidence for substituent effects on anticonvulsant properties by Kwiatkowski, W, Karolak-Wojciechowska, J, Obniska, J, Zejc, A

“…T = 295 K, Mo K alpha with lambda = 0.70930 A. Compound (I-6): C15H12N2O2, Mr = 252.26, monoclinic, P2(1)/c, a = 8.441 (3), b = 15.269 (1), c = 9.745 (2) A,…”
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Synthesis, anticonvulsant activity and 5-HT 1A, 5-HT 2A receptor affinity of new N-[(4-arylpiperazin-1-yl)-alkyl] derivatives of 2-azaspiro[4.4]nonane and [4.5]decane-1,3-dione by Obniska, J., Kołaczkowski, M., Bojarski, A.J., Duszyńska, B.

“…The synthesis, physicochemical and pharmacological properties of new N-[(4-arylpiperazin-1-yl)-alkyl]-2-azaspiro[4.4]nonane- ( 8a–c, 10a–d) and…”
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Synthesis and anticonvulsant activity of new fluorinated N-phenyl- and N-benzyl-2-azaspiro[4.4]nonane- and [4.5]decane-1,3-dione derivatives: Part III by Obniska, Jolanta, Kaminski, Krzysztof, Zagorska, Agnieszka, Dzierzawska-Majewska, Agnieszka, Karolak-Wojciechowska, Janina

“…A series of fluorinated N-phenyl and N-benzyl-2-azaspiro[4.4]nonane- and [4.5]decane-1.3-dione derivatives, with F and CF 3 substituents at the aromatic ring…”
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Anticonvulsant properties of N-(4-methylpiperazin-1-yl)- and N-[3-(4-methyl-piperazin-1-yl)propyl] derivatives of 3-aryl- and 3-spirocycloalkyl-pyrrolidine-2,5-dione by Obniska, Jolanta, Jurczyk, Sławomir, Zejc, Alfred, Kamiński, Krzysztof, Tatarczyńska, Ewa, Stachowicz, Katarzyna

“…Two series of N-(4-methylpiperazin-1-yl)- and N-[3-(4-methylpiperazin-1-yl)-propyl]-3-aryl- and 3-spirocycloalkyl-pyrrolidine-2,5-dione derivatives were…”
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Synthesis of N-alkyloamino- or arylo-imide derivatives of succinic acid by Lucka-Sobstel, B, Zejc, A, Obniska, J

“…10 new imide derivatives of phenylsuccinic acid possessing alkyloamine, alkyloaryl or aryl groups at nitrogen atom were obtained…”
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Synthesis, anticonvulsant properties and 5-HT1A/5-HT2A receptor affinity of new N-[(4-arylpiperazin-1-yl)-propyl]-2-aza-spiro[4.4]nonane and [4.5]decane-1,3-dione derivatives by Obniska, Jolanta, Kołaczkowski, Marcin, Charakchieva-Minol, Sijka, Nedza, Krystyna, Dybała, Małgorzata, Bojarski, Andrzej J

“…A series of twenty new N-[(4-arylpiperazin-1-yl)-propyl]-2-aza-spiro[4.4]nonane- and [4.5]decane-1,3-dione derivatives were synthesized and their…”
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Synthesis and 5-HT1A/5-HT2A receptor activity of N-(4-arylpiperazin-1-yl)alkyl derivatives of 2-azaspiro([4.4]nonane and [4.5]decane-1,3-dione by Obniska, Jolanta, Tatarczyńska, Ewa, Nikiforuk, Agnieszka, Charakchieva-Minol, Sijka, Duszyńska, Beata

“…Two series of N-[(4-arylpiperazin-1-yl)-alkyl]-2-azaspiro[4.4]nonane (5-10) and [4.5]decane-1,3-dione (11-16) derivatives were synthesized and their serotonin…”
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Synthesis and anticonvulsant properties of N-methylpyridyl derivatives of m- and p-bromophenylsuccinimides by Zejc, A, Obniska, J, Chojnacka-Wójcik, E, Tatarczyńska, E, Wiczyńska, B

“…The reaction of m- or p-bromophenylsuccinic acids with 2-aminomethylpyridines yielded respective N-methylpyridylimides 1-8. Only compounds 1 and 6 show…”
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Synthesis and anticonvulsant properties of some arylsuccinate methylpyridylimides by Zejc, A, Obniska, J, Wilimowski, M, Rutkowská, M, Witkowska, M, Barczyńska, J, Kedzierska-Goździk, L, Wojewódzki, W, Orzechowska-Juzwenko, K, Pławiak, T

“…In reaction of alpha-phenyl, alpha-p-chlorophenyl and alpha-m-chlorophenylsuccinic acid with various aminopyridines, N-pyridyl-substituted succinimides…”
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Synthesis and anticonvulsant properties of new N-piperazinylalkyl imides of succinic acid by Obniska, J, Kulig, K, Zejc, A

“…A number of N-[(4-aryl)- or (4-methyl)-l-piperazinyl)alkyl]imides of 3-aryl or 3,3-pentamethylenesuccinic acid were synthesized and tested for anticonvulsant…”
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Preliminary study on application of impregnated synthetic peptide TLC stationary phases for the pre-screening of 5-HT sub(1A) ligands by Zajdel, P, Bojarski, A J, Byrtus, H, Chon-Rzepa, G, Obniska, J, Chevallet, P, Martinez, J, Pawowski, M

“…Chromatographic parameters ([Delta]R sub(f)), defined as a difference in the migration of tested compound on the control and peptide impregnated silica gel TLC…”
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