Search Results - "Oblein, Lyanne"

Abstract C067: Correlation of keratin17 expression with tumor cell proliferation and invasion in PDAC by Sarkar, Shayan, Oblein, Lyanne, Horowitz, Michael, Escobar-Hoyos, Luisa, Marchenko, Natalia, Shroyer, Kenneth

“…Abstract Background: Pancreatic ductal adenocarcinoma (PDAC) shows variable degrees of differentiation, with both intratumoral, regional, and case to case…”
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Keratin 17 Expression Predicts Poor Clinical Outcome in Patients With Advanced Esophageal Squamous Cell Carcinoma by Haye, Kester, Babu, Sruthi, Oblein, Lyanne, Gupta, Rajarsi, Akalin, Ali, Escobar-Hoyos, Luisa F., Shroyer, Kenneth R.

“…The major roles of keratin 17 (K17) as a prognostic biomarker have been highlighted in a range of human malignancies. However, its relevance to esophageal…”
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Abstract C050: The unique metabolic signatures of keratin-17 expressing pancreatic ductal adenocarcinomas by Salem, Mahmoud M., Horowitz, Michael, Oblein, Lyanne, Pan, Chun-Hao, Marchenko, Natalia, Escobar-Hoyos, Luisa, Chen, Bo, Shroyer, Kenneth

“…Abstract Background: Overexpression of Keratin 17 (K17) is associated with upregulation of de novo pyrimidine synthesis, which is linked to resistance to…”
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Abstract B065: Biomarker approach to define tumor subtype in pancreatic ductal adenocarcinoma by Ho, Carson, Horowitz, Michael, Oblein, Lyanne, Sarkar, Shayan, Kobayashi, Soma, Bai, Karen, Marchenko, Natalia, Escobar-Hoyos, Luisa, Shroyer, Kenneth

“…Abstract Background: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal tumors with a predicted five-year survival rate in 2023 of 12%. Building…”
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Abstract B066: Keratin 17 and GATA6 expression in pancreatic ductal adenocarcinoma: A subtyping stratification approach by Horowitz, Michael, Oblein, Lyanne, Oentoro, Jaymie, Porwal, Anika, Jiang, Wei, Marchenko, Natalia, Escobar-Hoyos, Luisa, Shroyer, Kenneth

“…Abstract Background: Clinically and histologically identical pancreatic ductal adenocarcinomas (PDACs) differ in response to treatment, disease progression,…”
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Abstract B012: TP53 missense mutations and keratin 17 are negative prognostic biomarkers in pancreatic ductal adenocarcinoma by Arbelaez, Carlos Mauricio Mejia, Baraks, Gabriella, Oblein, Lyanne, Horowitz, Michael, Matrisian, Lynn, Shroyer, Kenneth, Escobar-Hoyos, Luisa Fernanda

“…Abstract Background: Cancer patients with similar clinical and pathologic characteristics may have different responses to treatments and survival, which may be…”
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Abstract B049: Comparison of keratin 17 and GATA6 as prognostic markers in pancreatic cancer by Horowitz, Michael, Oblein, Lyanne, Oentoro, Jaymie, Kasliwal, Saumya, Marchenko, Natalia D., Escobar-Hoyos, Luisa F., Shroyer, Kenneth R.

“…Abstract Background: Clinically and histologically identical pancreatic ductal adenocarcinomas (PDACs) differ in response to treatment, disease progression,…”
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Abstract A042: Keratin 17 is a negative prognostic and predictive biomarker in pancreatic ductal adenocarcinoma by Oblein, Lyanne, Roa-Peña, Lucia, Babu, Sruthi, Allard, Felicia D., Marchenko, Natalia D., Escobar-Hoyos, Luisa F., Shroyer, Kenneth R.

“…Abstract Background: There is an urgent need to understand why patients with clinically and histologically identical pancreatic ductal adenocarcinomas (PDACs)…”
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Abstract B085: K17-induced pyrimidine biosynthesis drives chemoresistance in PDAC by Lyu, Yinghuan, Shroyer, Kenneth, Pan, Chun-Hao, Tseng, Robert, Siraj, Md Afjalus, Rajacharya, Girish Halemirle, Chen, Bo, Donnelly, Katie L, Horowitz, Michael, Mejia Arbelaez, Carlos Mauricio, Chowdhury, Sumedha, Oblein, Lyanne, Marchenko, Natalia, Escobar-Hoyos, Luisa, Singh, Pankaj K.

“…Abstract Background: The 5-year survival rate of pancreatic cancer is extremely low compared with other cancers, although it has increased to 12% in 2023 in…”
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Abstract C063: Keratin 17 as a predictor of chemotherapy response in pancreatic ductal adenocarcinoma by Oblein, Lyanne, Roa, Lucia, Babu, Sruthi, Horowitz, Michael, Petricoin, Emanuel, Matrisian, Lynn M., Blais, Edik, Marchenko, Natalia, Allard, Felicia, Alkalin, Ali, Jiang, Wei, Larson, Brent, Hendifar, Andrew, Picozzi, Vincent, Choi, Minsig, Escobar-Hoyos, Luisa, Shroyer, Kenneth

“…Abstract Background: Two chemotherapies based on either gemcitabine- or 5-fluorouracil (5-FU) remain standard-of-care for pancreatic ductal adenocarcinomas…”
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Abstract B041: Keratin 17 excludes CD8-positive T cells and recruits CD163-positive macrophages in pancreatic ductal adenocarcinoma by Oblein, Lyanne, Babu, Sruthi, Torrente-Goncalves, Mariana, Roa, Lucia, Horowitz, Michael, Hasan, Mahmudul, Fassler, Danielle, Oentoro, Jaymie, Petricoin, Emanuel, Matrisian, Lynn M., Marchenko, Natalia, Blais, Edik, Allard, Felicia, Alkalin, Ali, Jiang, Wei, Larson, Brent, Hendifar, Andrew, Chen, Chao, Abousamra, Shahira, Samaras, Dimitris, Kurc, Tahsin, Saltz, Joel, Escobar-Hoyos, Luisa, Shroyer, Kenneth

“…Abstract Background. Keratin 17 (K17) is a negative prognostic and predictive biomarker, overexpressed in the biologically most aggressive forms of pancreatic…”
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Abstract C071: Keratin 17 excludes CD8-positive T cells and recruits CD163-positive macrophages in pancreatic ductal adenocarcinoma by Oblein, Lyanne, Horowitz, Michael, Hasan, Mahmudul, Babu, Sruthi, Torrente-Goncalves, Mariana, Roa, Lucia, Oentoro, Jaymie, Harper, Jason, Zheng, Xin Yao, Jiang, Wei, Hendifar, Andrew, Moshayedi, Natalie, Larson, Brent, Placencio-Hickok, Veronica, Blais, Edik, Petricoin, Emmanuel, Saltz, Joel, Marchenko, Natalia D., Escobar-Hoyos, Luisa F., Shroyer, Kenneth

“…Abstract Background: Keratin 17 (K17) is a negative prognostic biomarker, overexpressed in the biologically most aggressive forms of pancreatic ductal…”
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A Novel Framework for Characterization of Tumor-Immune Spatial Relationships in Tumor Microenvironment by Hasan, Mahmudul, Kaczmarzyk, Jakub R, Paredes, David, Oblein, Lyanne, Oentoro, Jaymie, Abousamra, Shahira, Horowitz, Michael, Samaras, Dimitris, Chen, Chao, Kurc, Tahsin, Shroyer, Kenneth R, Saltz, Joel

“…Understanding the impact of tumor biology on the composition of nearby cells often requires characterizing the impact of biologically distinct tumor regions…”
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