Search Results - "Oblander, Samantha A."

Loss of MMP-2 disrupts skeletal and craniofacial development and results in decreased bone mineralization, joint erosion and defects in osteoblast and osteoclast growth by Mosig, Rebecca A., Dowling, Oonagh, DiFeo, Analisa, Ramirez, Maria Celeste M., Parker, Ian C., Abe, Etsuko, Diouri, Janane, Aqeel, Aida Al, Wylie, James D., Oblander, Samantha A., Madri, Joseph, Bianco, Paolo, Apte, Suneel S., Zaidi, Mone, Doty, Stephen B., Majeska, Robert J., Schaffler, Mitchell B., Martignetti, John A.

“…The ‘vanishing bone’ or inherited osteolysis/arthritis syndromes represent a heterogeneous group of skeletal disorders characterized by mineralization defects…”
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Distinctive functions of membrane type 1 matrix-metalloprotease (MT1-MMP or MMP-14) in lung and submandibular gland development are independent of its role in pro-MMP-2 activation by Oblander, Samantha A., Zhou, Zhongjun, Gálvez, Beatriz G., Starcher, Barry, Shannon, John M., Durbeej, Madeleine, Arroyo, Alicia G., Tryggvason, Karl, Apte, Suneel S.

“…Membrane type 1-matrix metalloprotease (MT1-MMP or MMP-14) is a major activator of pro-MMP-2 and is essential for skeletal development. We show here that it is…”
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Distinct PTPmu-associated signaling molecules differentially regulate neurite outgrowth on E-, N-, and R-cadherin by Oblander, Samantha A., Brady-Kalnay, Susann M.

“…Classical cadherins play distinct roles in axon growth and guidance in the visual system, however, the signaling pathways they activate remain unclear. Growth…”
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Novel peptide mimetic small molecules of the HAV motif in N-cadherin inhibit N-cadherin-mediated neurite outgrowth and cell adhesion by Burden-Gulley, Susan M., Gates, Theresa J., Craig, Sonya E.L., Lou, Sara F., Oblander, Samantha A., Howell, Scott, Gupta, Mukur, Brady-Kalnay, Susann M.

“…The cell adhesion molecule, N-cadherin, stabilizes cell–cell junctions and promotes cellular migration during tissue morphogenesis in development. N-cadherin…”
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Membrane Type 1-Matrix Metalloproteinase Is Regulated by Chemokines Monocyte-Chemoattractant Protein-1/CCL2 and Interleukin-8/CXCL8 in Endothelial Cells during Angiogenesis by Gálvez, Beatriz G., Genís, Laura, Matías-Román, Salomón, Oblander, Samantha A., Tryggvason, Karl, Apte, Suneel S., Arroyo, Alicia G.

“…We have investigated the putative role and regulation of membrane type 1-matrix metalloproteinase (MT1-MMP) in angiogenesis induced by inflammatory factors of…”
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Matrix metalloproteinases: old dogs with new tricks by Somerville, Robert P T, Oblander, Samantha A, Apte, Suneel S

“…The matrix metalloproteinase family in humans comprises 23 enzymes, which are involved in many biological processes and diseases. It was previously thought…”
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E-cadherin promotes retinal ganglion cell neurite outgrowth in a protein tyrosine phosphatase-mu-dependent manner by Oblander, Samantha A., Ensslen-Craig, Sonya E., Longo, Frank M., Brady-Kalnay, Susann M.

“…During development of the visual system, retinal ganglion cells (RGCs) require cell–cell adhesion molecules and extracellular matrix proteins for axon growth…”
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An update on metalloproteases in the musculoskeletal system by Oblander, Samantha A., Somerville, Robert P.T., Apte, Suneel S.

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