Search Results - "Obi, Engels N."
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Sacubitril/Valsartan Initiation Among Veterans Who Are Renin-Angiotensin-Aldosterone System Inhibitor Naïve With Heart Failure and Reduced Ejection Fraction
Published in Journal of the American Heart Association (19-10-2021)“…Background Sacubitril/valsartan, a first-in-class angiotensin receptor neprilysin inhibitor, received US Food and Drug Administration approval in 2015 for…”
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Recurrent Clostridioides difficile infection worsens anxiety-related patient-reported quality of life
Published in Journal of patient-reported outcomes (14-05-2022)“…Background Clostridioides difficile infection (CDI) is associated with high recurrence rates impacting health-related quality of life (HrQOL). However,…”
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Incidence of acute kidney injury (AKI) and its impact on patient outcomes among adult hospitalized patients with carbapenem-resistant Gram-negative infections who received targeted treatment with a newer β-lactam or β-lactam/β-lactamase inhibitor-, polymyxin- or aminoglycoside-containing regimen
Published in Journal of antimicrobial chemotherapy (03-01-2024)“…Abstract Background Limited comparative data exist on acute kidney injury (AKI) risk and AKI-associated outcomes in hospitalized patients with…”
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Comparative evaluation of early treatment with ceftolozane/tazobactam versus ceftazidime/avibactam for non-COVID-19 patients with pneumonia due to multidrug-resistant Pseudomonas aeruginosa
Published in Journal of antimicrobial chemotherapy (11-09-2024)“…Ceftolozane/tazobactam and ceftazidime/avibactam are commonly used in patients with MDR-Pseudomonas aeruginosa (PSA) pneumonia (PNA). This study compared…”
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Risk assessment of post-discharge mortality among recently hospitalized Medicare heart failure patients with reduced or preserved ejection fraction
Published in Current medical research and opinion (01-02-2020)“…Objective: Targeted care management for hospitalized patients with acute decompensated heart failure (ADHF) with reduced or preserved ejection fraction…”
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Budget Impact Analysis of Fidaxomicin Versus Vancomycin for the Treatment of Clostridioides difficile Infection in the United States
Published in Infectious diseases and therapy (01-02-2022)“…Introduction Fidaxomicin is as effective as vancomycin in treating Clostridioides difficile infection (CDI) but more effective at preventing recurrence…”
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Adoption and Trends in Uptake of Updated ICD-10 Codes for Clostridioides difficile—A Retrospective Observational Study
Published in Open forum infectious diseases (01-12-2022)“…Abstract Background In October 2017, the single International Classification of Diseases, Tenth Revision (ICD-10), code for Clostridioides difficile infection…”
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A Retrospective Assessment of Guideline Adherence and Treatment Outcomes From Clostridioides difficile Infection Following the IDSA 2021 Clinical Guideline Update: Clostridioides difficile Infection
Published in Open forum infectious diseases (01-10-2024)“…The 2021 update to the Infectious Diseases Society of America infection (CDI) guidelines recommended fidaxomicin as the preferred treatment over vancomycin for…”
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Appropriate cleaning reduces potential risk of spore transmission from patients with Clostridioides difficile infection treated in outpatient infusion centers
Published in Anaerobe (01-10-2022)“…Patients with Clostridioides difficile infection (CDI) who receive treatment at outpatient infusion centers (OICs) pose a risk for spore transmission. We…”
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Health Care Costs for Patients with Heart Failure Escalate Nearly 3-Fold in Final Months of Life
Published in Journal of managed care & specialty pharmacy (01-12-2016)“…Heart failure (HF) is a severe chronic disease with growing prevalence and health care burden as well as high mortality. End-of-life cost data for patients…”
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Patients' Self-Reported Value of Avoiding Key Heart Failure Outcomes Differs Based on Disease Knowledge
Published in Journal of cardiac failure (01-08-2016)Get full text
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Quantifying the relative importance to patients of avoiding symptoms and outcomes of heart failure
Published in Current medical research and opinion (02-11-2017)“…Objective: To evaluate heart failure (HF) patients' disease knowledge and preferences for avoiding different disease outcomes. Methods: An online survey was…”
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Impact of Updated Clinical Practice Guidelines on Outpatient Treatment for Clostridioides difficile Infection and Associated Clinical Outcomes
Published in Open forum infectious diseases (01-10-2022)“…BackgroundThe 2017 Infectious Diseases Society of America/Society for Healthcare Epidemiology of America (IDSA/SHEA) Clostridium (Clostridioides) difficile…”
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Clinical and Economic Outcomes After Implementation of a Fidaxomicin Treatment Optimization and Access Pathway at a US Hospital System
Published in Infectious diseases and therapy (01-01-2023)“…Introduction This study aimed to evaluate the clinical and economic outcomes of implementing a Clostridiodes difficile infection (CDI) Treatment Optimization…”
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Placement of selected new FDA-approved drugs in Medicare Part D formularies, 2009-2013
Published in The American journal of managed care (01-06-2018)“…To assess formulary decisions by Part D plans for selected newly approved drugs. Retrospective cohort study. Formulary placement and restrictions were…”
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Risk Factors Associated with Severe Clostridioides difficile Infection in Patients with Cancer
Published in Infectious diseases and therapy (01-01-2023)“…Introduction Antibiotic use is a risk factor for Clostridioides difficile infection (CDI). Few studies have correlated use of prior antibiotic classes with…”
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Healthcare Costs Among Patients with Heart Failure: A Comparison of Costs between Matched Decedent and Survivor Cohorts
Published in Advances in therapy (2017)“…Introduction Prior research suggests increased costs during the final months of life, yet little is known about healthcare cost differences between patients…”
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HEALTHCARE COSTS AND RESOURCE UTILIZATION IN HEART FAILURE: DIFFERENCES BASED ON HEART FAILURE HISTORY
Published in Journal of the American College of Cardiology (17-03-2015)“…Methods: A retrospective study of medical and pharmacy claims data from a large US health plan (commercial and Medicare Advantage enrollees) was conducted…”
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RELATIONSHIP BETWEEN HEART FAILURE THERAPY AND COST BURDEN OF HEART FAILURE IN A MANAGED CARE POPULATION
Published in Journal of the American College of Cardiology (17-03-2015)“…Cohort assignment (2) was based on pharmacy claims for HF-related therapy (angiotensin-converting enzyme inhibitor, angiotensin-receptor blocker, beta blocker,…”
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