Search Results - "Obeyesekere, Nihal U."
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p202 self-associates through a sequence conserved among the members of the 200-family proteins
Published in FEBS letters (30-10-1998)“…Murine p202 is an interferon-inducible primarily nuclear phosphoprotein (52 kDa) whose expression in transfected cells inhibits colony formation. p202-binding…”
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Cyclic Peptides Incorporating 4-Carboxyphenylalanine and Phosphotyrosine Are Potent Inhibitors of pp60c- src
Published in Biochemistry (Easton) (02-05-2000)“…The protein tyrosine kinase, pp60c- src , is involved in cellular signaling and is activated during mitosis and in various tumors. We have been employing…”
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Stereospecific synthesis of 4-carboxyphenylalanine and derivatives for use in Fmoc-based solid-phase peptide synthesis
Published in Tetrahedron letters (09-09-1996)“…Starting from N α-benzyloxycarbonyl-L-tyrosine( O-triflate)benzyl ester, we have prepared enantiomerically pure 4-carboxyphenylalanine and…”
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Solid-phase synthesis of (tyrosyl-alanyl-glutamyl)n by segment condensation
Published in International journal of peptide and protein research (01-02-1994)“…(Tyr-Ala-Glu)n, n = 1-9, were synthesized by segment condensation using the Fmoc/tert-butyl protection strategy and solid-phase techniques. The C-terminal…”
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Tight-binding inhibitory sequences against pp60(c-src) identified using a random 15-amino-acid peptide library
Published in FEBS letters (16-12-1996)“…A bacteriophage peptide library containing a random 15-amino-acid insert was screened for identification of peptide sequence(s) that bind pp60(c-src)…”
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Cyclic Peptides Incorporating 4-Carboxyphenylalanine and Phosphotyrosine Are Potent Inhibitors of pp60 c- src
Published in Biochemistry (Easton) (01-05-2000)Get full text
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Cyclic peptides incorporating 4-carboxyphenylalanine and phosphotyrosine are potent inhibitors of pp60(c-)(src)
Published in Biochemistry (Easton) (02-05-2000)“…The protein tyrosine kinase, pp60(c-)(src), is involved in cellular signaling and is activated during mitosis and in various tumors. We have been employing…”
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Tight-binding inhibitory sequences against pp60 c−src identified using a random 15-amino-acid peptide library
Published in FEBS letters (16-12-1996)“…A bacteriophage peptide library containing a random 15-amino-acid insert was screened for identification of peptide sequence(s) that bind pp60 c−src …”
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A Synthetic Peptidic Substrate of Minimal Size and Semi-optimal Sequence for the Protein Tyrosine Kinase pp60c-src
Published in Archives of biochemistry and biophysics (01-02-1996)“…We used a novel approach to determine the minimal size and semioptimal sequence of a peptide to serve as an inhibitor and/or substrate for the protein tyrosine…”
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Cyclic Peptides as Probes of the Substrate Binding Site of the Cytosolic Tyrosine Kinase, pp60c-src
Published in Archives of biochemistry and biophysics (01-07-1998)“…A series of 48 cyclic peptides based on the amino acid sequence surrounding the autophosphorylation site of pp60c-srcwas synthesized and each was tested as…”
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Silicon-functionalized silyl enol ethers. Part 2. Silyl enol ethers bearing stereogenic silicon atoms and chiral alkoxy groups: the effect of these groups upon the facial selectivity of the epoxidation of an enol double bond
Published in Journal of organic chemistry (01-02-1988)Get full text
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Enhanced phagocytosis activity of cyclic analogs of tuftsin
Published in Biochemical pharmacology (01-03-1995)“…Cyclic analogs of the physiological immunostimulating peptide tuftsin (Thr-Lys-Pro-Arg), cyclo(Thr-Lys-Pro-Arg-Gly) (ctuf-G) and cyclo(Thr-Lys-Pro-Arg-Asp)…”
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A Tyrphostin-Derived Inhibitor of Protein Tyrosine Kinases: Isolation and Characterization
Published in Archives of biochemistry and biophysics (10-11-1995)“…We recently reported that tyrphostin 23 (3,4-dihydroxybenzylidene malononitrile) is unstable in solution and that some of the degradation products are better…”
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