Search Results - "Oberlick, Elaine M"

BRD9 defines a SWI/SNF sub-complex and constitutes a specific vulnerability in malignant rhabdoid tumors by Wang, Xiaofeng, Wang, Su, Troisi, Emma C., Howard, Thomas P., Haswell, Jeffrey R., Wolf, Bennett K., Hawk, William H., Ramos, Pilar, Oberlick, Elaine M., Tzvetkov, Evgeni P., Ross, Aaron, Vazquez, Francisca, Hahn, William C., Park, Peter J., Roberts, Charles W. M.

“…Bromodomain-containing protein 9 (BRD9) is a recently identified subunit of SWI/SNF(BAF) chromatin remodeling complexes, yet its function is poorly understood…”
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Author Correction: BRD9 defines a SWI/SNF sub-complex and constitutes a specific vulnerability in malignant rhabdoid tumors by Wang, Xiaofeng, Wang, Su, Troisi, Emma C., Howard, Thomas P., Haswell, Jeffrey R., Wolf, Bennett K., Hawk, William H., Ramos, Pilar, Oberlick, Elaine M., Tzvetkov, Evgeni P., Ross, Aaron, Vazquez, Francisca, Hahn, William C., Park, Peter J., Roberts, Charles W. M.

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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GATA1 deletion in human pluripotent stem cells increases differentiation yield and maturity of neutrophils by Harper, Thomas C., Oberlick, Elaine M., Smith, Tomas J., Nunes, Duncan E., Bray, Mark-Anthony, Park, Seonmi, Driscoll, Corey D., Mowbray, Sarah F., Antczak, Christophe

“…Human pluripotent stem cell (hPSC)-derived tissues can be used to model diseases in cell types that are challenging to harvest and study at-scale, such as…”
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MDM2 and MDM4 Are Therapeutic Vulnerabilities in Malignant Rhabdoid Tumors by Howard, Thomas P, Arnoff, Taylor E, Song, Melinda R, Giacomelli, Andrew O, Wang, Xiaofeng, Hong, Andrew L, Dharia, Neekesh V, Wang, Su, Vazquez, Francisca, Pham, Minh-Tam, Morgan, Ann M, Wachter, Franziska, Bird, Gregory H, Kugener, Guillaume, Oberlick, Elaine M, Rees, Matthew G, Tiv, Hong L, Hwang, Justin H, Walsh, Katherine H, Cook, April, Krill-Burger, John M, Tsherniak, Aviad, Gokhale, Prafulla C, Park, Peter J, Stegmaier, Kimberly, Walensky, Loren D, Hahn, William C, Roberts, Charles W M

“…Malignant rhabdoid tumors (MRT) are highly aggressive pediatric cancers that respond poorly to current therapies. In this study, we screened several MRT cell…”
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Rhabdoid Tumors Are Sensitive to the Protein-Translation Inhibitor Homoharringtonine by Howard, Thomas P, Oberlick, Elaine M, Rees, Matthew G, Arnoff, Taylor E, Pham, Minh-Tam, Brenan, Lisa, DoCarmo, Mariana, Hong, Andrew L, Kugener, Guillaume, Chou, Hsien-Chao, Drosos, Yiannis, Mathias, Kaeli M, Ramos, Pilar, Seashore-Ludlow, Brinton, Giacomelli, Andrew O, Wang, Xiaofeng, Freeman, 3rd, Burgess B, Blankenship, Kaley, Hoffmann, Lauren, Tiv, Hong L, Gokhale, Prafulla C, Johannessen, Cory M, Stewart, Elizabeth A, Schreiber, Stuart L, Hahn, William C, Roberts, Charles W M

“…Rhabdoid tumors are devastating pediatric cancers in need of improved therapies. We sought to identify small molecules that exhibit and efficacy against…”
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Small-Molecule and CRISPR Screening Converge to Reveal Receptor Tyrosine Kinase Dependencies in Pediatric Rhabdoid Tumors by Oberlick, Elaine M., Rees, Matthew G., Seashore-Ludlow, Brinton, Vazquez, Francisca, Nelson, Geoffrey M., Dharia, Neekesh V., Weir, Barbara A., Tsherniak, Aviad, Ghandi, Mahmoud, Krill-Burger, John M., Meyers, Robin M., Wang, Xiaofeng, Montgomery, Phil, Root, David E., Bieber, Jake M., Radko, Sandi, Cheah, Jaime H., Hon, C. Suk-Yee, Shamji, Alykhan F., Clemons, Paul A., Park, Peter J., Dyer, Michael A., Golub, Todd R., Stegmaier, Kimberly, Hahn, William C., Stewart, Elizabeth A., Schreiber, Stuart L., Roberts, Charles W.M.

“…Cancer is often seen as a disease of mutations and chromosomal abnormalities. However, some cancers, including pediatric rhabdoid tumors (RTs), lack recurrent…”
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Abstract 2867: MDM2 and MDM4 are therapeutic vulnerabilities in malignant rhabdoid tumors by Howard, Thomas P., Arnoff, Taylor E., Song, Melinda R., Giacomelli, Andrew O., Wang, Xiaofeng, Hong, Andrew L., Dharia, Neekesh V., Wang, Su, Vazquez, Francisca, Pham, Minh-Tam, Morgan, Ann M., Wachter, Franziska, Bird, Gregory H., Kugener, Guillaume, Oberlick, Elaine M., Rees, Matthew G., Tiv, Hong, Hwang, Justin H., Walsh, Katherine H., Cook, April, Krill-Burger, John M., Tsherniak, Aviad, Gokhale, Prafulla C., Park, Peter J., Stegmaier, Kimberly, Walensky, Loren D., Hahn, William C., Roberts, Charles W.

“…Abstract Malignant rhabdoid tumors (MRT) are aggressive cancers of early childhood that are largely resistant to traditional therapies. MRT exhibit a…”
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Abstract 342: Silencing of IGF1R induces mesenchymal-to-epithelial transition and inhibits the metastatic properties of triple negative breast cancer cells by Taliaferro-Smith, LaTonia D., Oberlick, Elaine M., Liu, Tongriu, Adams, Amy, Eggers, Carrie, Kline, Erik, Nagaraju, Ganji P., Cohen, Cynthia, Marcus, Adam, O'Regan, Ruth

“…Abstract Next to skin cancer, breast cancer is the second most common cancer diagnosed among American women and affects nearly 1.3 million women worldwide each…”
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Small-molecule and CRISPR screening converge to reveal RTK dependencies in pediatric rhabdoid tumors by Oberlick, Elaine M., Rees, Matthew G., Seashore-Ludlow, Brinton, Vazquez, Francisca, Nelson, Geoffrey M., Dharia, Neekesh V., Weir, Barbara A., Tsherniak, Aviad, Ghandi, Mahmoud, Krill-Burger, John M., Meyers, Robin M., Wang, Xiaofeng, Montgomery, Phil, Root, David E., Bieber, Jake M., Radko, Sandi, Cheah, Jaime H., Hon, C. Suk-Yee, Shamji, Alykhan F., Clemons, Paul A., Park, Peter J., Dyer, Michael A., Golub, Todd R., Stegmaier, Kimberly, Hahn, William C., Stewart, Elizabeth A., Schreiber, Stuart L., Roberts, Charles W. M.

“…Cancer is often seen as a disease of mutations and chromosomal abnormalities. However, some cancers, including pediatric rhabdoid tumors (RTs), lack recurrent…”
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