Search Results - "Oberlander, T. F."

Sustained Neurobehavioral Effects of Exposure to SSRI Antidepressants During Development: Molecular to Clinical Evidence by Oberlander, T F, Gingrich, J A, Ansorge, M S

“…Selective serotonin reuptake inhibitor (SSRI) antidepressants are frequently used in the management of antenatal maternal mood disturbances. SSRIs readily…”
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Prevalence and characteristics of adults with fetal alcohol spectrum disorder in corrections: a Canadian case ascertainment study by McLachlan, K, McNeil, A, Pei, J, Brain, U, Andrew, G, Oberlander, T F

“…Individuals with fetal alcohol spectrum disorder (FASD) experience a range of cognitive, affective, and physical deficits following prenatal alcohol exposure…”
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A register study of the impact of stopping third trimester selective serotonin reuptake inhibitor exposure on neonatal health by Warburton, W., Hertzman, C., Oberlander, T. F.

“…Warburton W, Hertzman C, Oberlander TF. A register study of the impact of stopping third trimester selective serotonin reuptake inhibitor exposure on neonatal…”
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Expert consensus on neurodevelopmental outcomes in pregnancy pharmacovigilance studies by Bromley, R L, Bickle Graz, M, Bluett-Duncan, M, Chambers, C, Damkier, P, Dietrich, K, Dolk, H, Grant, K, Mattson, S, Meador, K J, Nordeng, H, Oberlander, T F, Ornoy, A, Revet, A, Richardson, J, Rovet, J, Schuler-Faccini, L, Smearman, E, Simms, V, Vorhees, C, Wide, K, Wood, A, Yates, L, Ystrom, E, Supraja, T A, Adams, J

“…Exposure to certain medications can disrupt processes of fetal development, including brain development, leading to a continuum of neurodevelopmental…”
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Cytochrome P4502D6 ( ) Gene Locus Heterogeneity: Characterization of Gene Duplication Events by Gaedigk, A, Ndjountché, L, Divakaran, K, DiAnne Bradford, L, Zineh, I, Oberlander, T F, Brousseau, D C, McCarver, D G, Johnson, J A, Alander, S W, Wayne Riggs, K, Steven Leeder, J

“…Duplications and multiplications of active CYP2D6 genes can cause ultrarapid drug metabolism and lead to therapeutic failure. Multiple functional and…”
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The application of epiphenotyping approaches to DNA methylation array studies of the human placenta by Khan, A, Inkster, A. M, Peéaherrera, M. S, King, S, Kildea, S, Oberlander, T. F, Olson, D. M, Vaillancourt, C, Brain, U, Beraldo, E. O, Beristain, A. G, Clifton, V. L, Del Gobbo, G. F, Lam, W. L, Metz, G. A. S, Ng, J. W. Y, Price, E. M, Schuetz, J. M, Yuan, V, Portales-Casamar, É, Robinson, W. P

“…Genome-wide DNA methylation (DNAme) profiling of the placenta with Illumina Infinium Methylation bead arrays is often used to explore the connections between…”
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Infant serotonin transporter (SLC6A4) promoter genotype is associated with adverse neonatal outcomes after prenatal exposure to serotonin reuptake inhibitor medications by Oberlander, T F, Bonaguro, R J, Misri, S, Papsdorf, M, Ross, C J D, Simpson, E M

“…Reduced Apgar scores and birth weight, increased risk of respiratory distress, jitteriness and increased tone have been reported in up to 30% of neonates with…”
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Developmental changes in serotonin signaling: Implications for early brain function, behavior and adaptation by Brummelte, S, Mc Glanaghy, E, Bonnin, A, Oberlander, T.F

“…Highlights • The 5HT system starts to develop early and plays a crucial role in brain maturation. • Alterations in the serotonergic tone during development can…”
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Infants and adults have similar regional functional brain organization for the perception of emotions by Rotem-Kohavi, N., Oberlander, T.F., Virji-Babul, N.

“…•Graph analysis was applied during emotional faces observation in infants and adults.•Parietal and temporal nodes are most influential in the network in both…”
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Prenatal exposure to maternal depression is related to the functional connectivity organization underlying emotion perception in 8-10-month-old infants – Preliminary findings by Rotem-Kohavi, N., Virji-Babul, N., Oberlander, T.F.

“…•We tested association between prenatal mood and infants’ response to emotions.•Network organization for viewing emotional faces interacted with prenatal…”
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Depression during pregnancy: the potential impact of increased risk for fetal aneuploidy on maternal mood by Hippman, C, Oberlander, TF, Honer, WG, Misri, S, Austin, JC

“…Depression during pregnancy can have serious consequences for families. Indications of fetal aneuploidy can induce maternal stress, a risk factor for…”
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Complex chronic conditions among children born to women with schizophrenia by Toufeili, A., Cohen, E., Ray, J.G., Wilton, A.S., Brown, H.K., Saunders, N.R., Dennis, C.L., Holloway, A.C., Morrison, K.M., Hanley, G.E., Oberlander, T.F., Bérard, A., Tu, K., Barker, L.C., Vigod, S.N.

“…Maternal schizophrenia is linked to complications in offspring near the time of birth. Whether there is also a higher future risk of the child having a complex…”
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Demographic and Therapeutic Determinants of Pain Reactivity in Very Low Birth Weight Neonates at 32 Weeks' Postconceptional Age by Grunau, Ruth Eckstein, Oberlander, Tim F, Whitfield, Michael F, Fitzgerald, Colleen, Lee, Shoo K

“…Management of pain in very low birth weight infants is limited by a lack of empiric knowledge about the multiple determinants of biobehavioral reactivity in…”
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Biobehavioral Pain Responses in Former Extremely Low Birth Weight Infants at Four Months' Corrected Age by Oberlander, Tim F, Grunau, Ruth Eckstein, Whitfield, Michael F, Fitzgerald, Colleen, Pitfield, Sandy, Saul, J. Philip

“…To compare biobehavioral responses to acute pain at 4 months' corrected age between former extremely low birth weight (ELBW) infants and term-born controls…”
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Infants Tolerate Spinal Anesthesia with Minimal Overall Autonomic Changes: Analysis of Heart Rate Variability in Former Premature Infants Undergoing Hernia Repair by Oberlander, Tim F., Berde, Charles B., Lam, Kar H., Rappaport, L. A., Saul, J. Philip

“…Unlike adults, neonates tolerate high thoracic spinal anesthesia with minimal changes in heart rate (HR) and arterial blood pressure.To examine the potential…”
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Antidepressant use during pregnancy and serotonin transporter genotype (SLC6A4) Affect newborn serum reelin levels by Brummelte, S., Galea, L.A.M., Devlin, A.M., Oberlander, T.F.

“…This study was undertaken to determine whether altered early serotonin signaling either via gestational serotonin reuptake inhibitor (SRI) exposure or genetic…”
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Beliefs about pain among professionals working with children with significant neurologic impairment by Oberlander, Tim F, O'Donnell, Maureen E

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Genetic variation in catechol-O-methyltransferase modifies effects of clonidine treatment in chronic fatigue syndrome by Hall, K T, Kossowsky, J, Oberlander, T F, Kaptchuk, T J, Saul, J P, Wyller, V B, Fagermoen, E, Sulheim, D, Gjerstad, J, Winger, A, Mukamal, K J

“…Clonidine, an α2-adrenergic receptor agonist, decreases circulating norepinephrine and epinephrine, attenuating sympathetic activity. Although catechol- O…”
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The developmental character of cardiac autonomic responses to an acute noxious event in 4- and 8-month-old healthy infants by OBERLANDER, T. F, GRUNAU, R. E, PITFIELD, S, WHITFIELD, M. F, SAUL, J. P

“…Heart rate (HR) has been widely studied as a measure of an individual's response to painful stimuli. It remains unclear whether changes in mean HR or the…”
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Biobehavioral Responses to Acute Pain in Adolescents with a Significant Neurologic Impairment by Oberlander, Tim F, Gilbert, Cheryl A, Chambers, Christine T, O'Donnell, Maureen E, Craig, Kenneth D

“…OBJECTIVE:To further understand acute pain response in children with a significant neurologic impairment (SNI), we undertook a descriptive…”
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