Search Results - "Oberemm, Axel"

Proteomic analysis of 3-MCPD and 3-MCPD dipalmitate-induced toxicity in rat kidney by Sawada, Stefanie, Oberemm, Axel, Buhrke, Thorsten, Merschenz, Julia, Braeuning, Albert, Lampen, Alfonso

“…3-Chloropropane-1,2-diol (3-MCPD) and its fatty acid esters are formed during thermal treatment of fat-containing foodstuff in the presence of salt…”
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Proteomic analysis of hepatic effects of okadaic acid in HepaRG human liver cells by Wuerger, Leonie T D, Birkholz, Greta, Oberemm, Axel, Sieg, Holger, Braeuning, Albert

“…The marine biotoxin okadaic acid (OA) is produced by dinoflagellates and enters the human food chain by accumulating in the fatty tissue of filter-feeding…”
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Proteomic responses of human intestinal Caco-2 cells exposed to silver nanoparticles and ionic silver by Oberemm, Axel, Hansen, Ulf, Böhmert, Linda, Meckert, Christine, Braeuning, Albert, Thünemann, Andreas F., Lampen, Alfonso

“…Even although quite a number of studies have been performed so far to demonstrate nanoparticle‐specific effects of substances in living systems, clear evidence…”
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The Use of Human Biomonitoring to Assess Occupational Exposure to PAHs in Europe: A Comprehensive Review by Louro, Henriqueta, Gomes, Bruno Costa, Saber, Anne Thoustrup, Iamiceli, Anna Laura, Göen, Thomas, Jones, Kate, Katsonouri, Andromachi, Neophytou, Christiana M, Vogel, Ulla, Ventura, Célia, Oberemm, Axel, Duca, Radu Corneliu, Fernandez, Mariana F, Olea, Nicolas, Santonen, Tiina, Viegas, Susana, Silva, Maria João

“…Polycyclic aromatic hydrocarbons (PAHs) are among the chemicals with proven impact on workers’ health. The use of human biomonitoring (HBM) to assess…”
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Pharmacokinetics explain in vivo/in vitro discrepancies of carcinogen-induced gene expression alterations in rat liver and cultivated hepatocytes by Schug, Markus, Stöber, Regina, Heise, Tanja, Mielke, Hans, Gundert-Remy, Ursula, Godoy, Patricio, Reif, Raymond, Blaszkewicz, Meinolf, Ellinger-Ziegelbauer, Heidrun, Ahr, Hans-Jürgen, Selinski, Silvia, Günther, Georgia, Marchan, Rosemarie, Sachinidis, Agapios, Nüssler, Andreas, Oberemm, Axel, Hengstler, Jan G.

“…Cultivated hepatocytes represent a well-established in vitro system. However, the applicability of hepatocytes in toxicogenomics is still controversially…”
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Identification of an enzymatically formed glutathione conjugate of the cyanobacterial hepatotoxin microcystin-LR: the first step of detoxication by Pflugmacher, Stephan, Wiegand, Claudia, Oberemm, Axel, Beattie, Kenneth A., Krause, Eberhard, Codd, Geoffrey A., Steinberg, Christian E.W.

“…Cyanobacterial toxins have adverse effects on mammals, birds and fish and are being increasingly recognised as a potent stress factor and health hazard factor…”
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Comparative proteomic data of M13SV1 human breast epithelial cells and their tumorigenic variants under treatment with estrogenic compounds by Braeuning, Albert, Schmidt, Claudia, Oberemm, Axel, Lampen, Alfonso

“…Data from a comparative proteomic analysis of three human breast epithelial cell lines are presented. M13SV1 cells and their tumorigenic derivatives…”
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The contributions of specific amino acid side chains to signal intensities of peptides in matrix-assisted laser desorption/ionization mass spectrometry by Baumgart, Sabine, Lindner, Yvonne, Kühne, Ronald, Oberemm, Axel, Wenschuh, Holger, Krause, Eberhard

“…Matrix‐assisted laser desorption/ionization mass spectrometry (MALDI‐MS) analysis of complex peptide mixtures is often hampered by signal suppression effects…”
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Uptake and effects of microcystin-LR on detoxication enzymes of early life stages of the zebra fish (Danio rerio) by Wiegand, Claudia, Pflugmacher, Stephan, Oberemm, Axel, Meems, Nanke, Beattie, Kenneth A., Steinberg, Christian E. W., Codd, Geoffrey A.

“…The effects of cyanotoxins on fish have been studied mainly in adults, rather than in early life stages which could be more sensitive or, in view of their…”
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Differential signatures of protein expression in marmoset liver and thymus induced by single-dose TCDD treatment by Oberemm, Axel, Meckert, Christine, Brandenburger, Linda, Herzig, Andrea, Lindner, Yvonne, Kalenberg, Kareen, Krause, Eberhard, Ittrich, Carina, Kopp-Schneider, Annette, Stahlmann, Ralf, Richter-Reichhelm, Hans-Bernhard, Gundert-Remy, Ursula

“…2,3,7,8-Tetrachlorodibenzo- p-dioxin (TCDD) is an ubiquitously distributed environmental pollutant. Health effects have been studied intensively, but low-dose…”
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Proteomic analysis of 2-monochloropropanediol (2-MCPD) and 2-MCPD dipalmitate toxicity in rat kidney and liver in a 28-days study by Frenzel, Falko, Oberemm, Axel, Braeuning, Albert, Lampen, Alfonso

“…2-monochloropropanediol (2-MCPD), 3-monochloropropanediol (3-MCPD) and their fatty acid esters have recently been identified as heat-induced contaminants in…”
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Proteomic effects of repeated-dose oral exposure to 2-monochloropropanediol and its dipalmitate in rat testes by Frenzel, Falko, Oberemm, Axel, Lampen, Alfonso, Braeuning, Albert

“…2- and 3-monochloropropanediol (2-MCPD) and their fatty acid esters are food contaminants which are concomitantly formed upon thermal treatment of foodstuff…”
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Analysis of 3-MCPD- and 3-MCPD dipalmitate-induced proteomic changes in rat liver by Braeuning, Albert, Sawada, Stefanie, Oberemm, Axel, Lampen, Alfonso

“…3-Monochloropropane-1,2-diol (3-MCPD) and 3-MCPD fatty acid esters are process contaminants in foodstuff which are generated during thermal treatment…”
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3-MCPD as contaminant in processed foods: State of knowledge and remaining challenges by Eisenreich, Andreas, Monien, Bernhard H., Götz, Mario E., Buhrke, Thorsten, Oberemm, Axel, Schultrich, Katharina, Abraham, Klaus, Braeuning, Albert, Schäfer, Bernd

“…•3-Chloro-1,2-propanediol (3-MCPD) is present as contaminants in different foods.•3-MCPD is a non-genotoxic compound exhibiting secondary carcinogenic…”
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Proteomic analysis of 3-MCPD and 3-MCPD dipalmitate toxicity in rat testis by Sawada, Stefanie, Oberemm, Axel, Buhrke, Thorsten, Meckert, Christine, Rozycki, Christel, Braeuning, Albert, Lampen, Alfonso

“…Thermal treatment of foodstuff containing fats and salt promotes the formation of 3-chloropropane-1,2-diol (3-MCPD) and its fatty acid esters. 3-MCPD-exposed…”
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Biomarkers of effect as determined in human biomonitoring studies on hexavalent chromium and cadmium in the period 2008–2020 by Ventura, Célia, Gomes, Bruno Costa, Oberemm, Axel, Louro, Henriqueta, Huuskonen, Pasi, Mustieles, Vicente, Fernández, Mariana F., Ndaw, Sophie, Mengelers, Marcel, Luijten, Mirjam, Gundacker, Claudia, Silva, Maria João

“…A number of human biomonitoring (HBM) studies have presented data on exposure to hexavalent chromium [Cr(VI)] and cadmium (Cd), but comparatively few include…”
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Comparative proteomic analysis of 2-MCPD- and 3-MCPD-induced heart toxicity in the rat by Schultrich, Katharina, Frenzel, Falko, Oberemm, Axel, Buhrke, Thorsten, Braeuning, Albert, Lampen, Alfonso

“…The chlorinated propanols 2- and 3-monochloropropanediol (MCPD), and their fatty acid esters have gained public attention due to their frequent occurrence as…”
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Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations by Albrecht, Wiebke, Kappenberg, Franziska, Brecklinghaus, Tim, Stoeber, Regina, Marchan, Rosemarie, Zhang, Mian, Ebbert, Kristina, Kirschner, Hendrik, Grinberg, Marianna, Leist, Marcel, Moritz, Wolfgang, Cadenas, Cristina, Ghallab, Ahmed, Reinders, Jörg, Vartak, Nachiket, van Thriel, Christoph, Golka, Klaus, Tolosa, Laia, Castell, José V., Damm, Georg, Seehofer, Daniel, Lampen, Alfonso, Braeuning, Albert, Buhrke, Thorsten, Behr, Anne-Cathrin, Oberemm, Axel, Gu, Xiaolong, Kittana, Naim, van de Water, Bob, Kreiling, Reinhard, Fayyaz, Susann, van Aerts, Leon, Smedsrød, Bård, Ellinger-Ziegelbauer, Heidrun, Steger-Hartmann, Thomas, Gundert-Remy, Ursula, Zeigerer, Anja, Ullrich, Anett, Runge, Dieter, Lee, Serene M. L., Schiergens, Tobias S., Kuepfer, Lars, Aguayo-Orozco, Alejandro, Sachinidis, Agapios, Edlund, Karolina, Gardner, Iain, Rahnenführer, Jörg, Hengstler, Jan G.

“…Drug-induced liver injury (DILI) cannot be accurately predicted by animal models. In addition, currently available in vitro methods do not allow for the…”
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Comparative proteomic analysis of silver nanoparticle effects in human liver and intestinal cells by Braeuning, Albert, Oberemm, Axel, Görte, Josephine, Böhmert, Linda, Juling, Sabine, Lampen, Alfonso

“…Consumers are orally exposed to nanoparticulate or soluble species of the non‐essential element silver due to its use in food contact materials or as a food…”
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Fish early life stage tests as a tool to assess embryotoxic potentials in small streams by Luckenbach, T, Kilian, M, Triebskorn, R, Oberemm, A

“…Early life stage (ELS) studies with brown trout (Salmo trutta f. fario L.) and stone loach (Barbatula barbatula L.) were performed between 1995 and 2000 to…”
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