Search Results - "Ober, Elke A."

Vegfc Regulates Bipotential Precursor Division and Prox1 Expression to Promote Lymphatic Identity in Zebrafish by Koltowska, Katarzyna, Lagendijk, Anne Karine, Pichol-Thievend, Cathy, Fischer, Johanna C., Francois, Mathias, Ober, Elke A., Yap, Alpha S., Hogan, Benjamin M.

“…Lymphatic vessels arise chiefly from preexisting embryonic veins. Genetic regulators of lymphatic fate are known, but how dynamic cellular changes contribute…”
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Interplay between Wnt2 and Wnt2bb controls multiple steps of early foregut-derived organ development by Poulain, Morgane, Ober, Elke A

“…The vertebrate liver, pancreas and lung arise in close proximity from the multipotent foregut endoderm. Tissue-explant experiments uncovered instructive…”
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EphrinB1/EphB3b Coordinate Bidirectional Epithelial-Mesenchymal Interactions Controlling Liver Morphogenesis and Laterality by Cayuso, Jordi, Dzementsei, Aliaksandr, Fischer, Johanna C., Karemore, Gopal, Caviglia, Sara, Bartholdson, Josefin, Wright, Gavin J., Ober, Elke A.

“…Positioning organs in the body often requires the movement of multiple tissues, yet the molecular and cellular mechanisms coordinating such movements are…”
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Lineage tracing identifies heterogeneous hepatoblast contribution to cell lineages and postembryonic organ growth dynamics by Unterweger, Iris. A, Klepstad, Julie, Hannezo, Edouard, Lundegaard, Pia R, Trusina, Ala, Ober, Elke A

“…To meet the physiological demands of the body, organs need to establish a functional tissue architecture and adequate size as the embryo develops to adulthood…”
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Divergence of zebrafish and mouse lymphatic cell fate specification pathways by van Impel, Andreas, Zhao, Zhonghua, Hermkens, Dorien M A, Roukens, M Guy, Fischer, Johanna C, Peterson-Maduro, Josi, Duckers, Henricus, Ober, Elke A, Ingham, Philip W, Schulte-Merker, Stefan

“…In mammals, the homeodomain transcription factor Prox1 acts as the central regulator of lymphatic cell fate. Its restricted expression in a subset of cardinal…”
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Bone Morphogenetic Protein 2 Signaling Negatively Modulates Lymphatic Development in Vertebrate Embryos by Dunworth, William P, Cardona-Costa, Jose, Bozkulak, Esra Cagavi, Kim, Jun-Dae, Meadows, Stryder, Fischer, Johanna C, Wang, Yeqi, Cleaver, Ondine, Qyang, Yibing, Ober, Elke A, Jin, Suk-Won

“…RATIONALE:The emergence of lymphatic endothelial cells (LECs) seems to be highly regulated during development. Although several factors that promote the…”
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A morphogenetic EphB/EphrinB code controls hepatopancreatic duct formation by Thestrup, M. Ilcim, Caviglia, Sara, Cayuso, Jordi, Heyne, Ronja L. S., Ahmad, Racha, Hofmeister, Wolfgang, Satriano, Letizia, Wilkinson, David G., Andersen, Jesper B., Ober, Elke A.

“…The hepatopancreatic ductal (HPD) system connects the intrahepatic and intrapancreatic ducts to the intestine and ensures the afferent transport of the bile…”
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The Spinster Homolog, Two of Hearts, Is Required for Sphingosine 1-Phosphate Signaling in Zebrafish by Osborne, Nick, Brand-Arzamendi, Koroboshka, Ober, Elke A., Jin, Suk-Won, Verkade, Heather, Holtzman, Nathalia Glickman, Yelon, Deborah, Stainier, Didier Y.R.

“…The bioactive lipid sphingosine 1-phosphate (S1P) and its G protein-coupled receptors play critical roles in cardiovascular, immunological, and neural…”
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Genetic and cellular analyses of zebrafish atrioventricular cushion and valve development by Beis, Dimitris, Bartman, Thomas, Jin, Suk-Won, Scott, Ian C, D'Amico, Leonard A, Ober, Elke A, Verkade, Heather, Frantsve, Julie, Field, Holly A, Wehman, Ann, Baier, Herwig, Tallafuss, Alexandra, Bally-Cuif, Laure, Chen, Jau-Nian, Stainier, Didier Y R, Jungblut, Benno

“…Defects in cardiac valve morphogenesis and septation of the heart chambers constitute some of the most common human congenital abnormalities. Some of these…”
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Bmp and Fgf signaling are essential for liver specification in zebrafish by Shin, Donghun, Shin, Chong Hyun, Tucker, Jennifer, Ober, Elke A, Rentzsch, Fabian, Poss, Kenneth D, Hammerschmidt, Matthias, Mullins, Mary C, Stainier, Didier Y R

“…Based on data from in vitro tissue explant and ex vivo cell/bead implantation experiments, Bmp and Fgf signaling have been proposed to regulate hepatic…”
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ahctf1 and kras mutations combine to amplify oncogenic stress and restrict liver overgrowth in a zebrafish model of hepatocellular carcinoma by Morgan, Kimberly J, Doggett, Karen, Geng, Fansuo, Mieruszynski, Stephen, Whitehead, Lachlan, Smith, Kelly A, Hogan, Benjamin M, Simons, Cas, Baillie, Gregory J, Molania, Ramyar, Papenfuss, Anthony T, Hall, Thomas E, Ober, Elke A, Stainier, Didier Y R, Gong, Zhiyuan, Heath, Joan K

“…The nucleoporin (NUP) ELYS, encoded by , is a large multifunctional protein with essential roles in nuclear pore assembly and mitosis. Using both larval and…”
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Minor class splicing shapes the zebrafish transcriptome during development by Markmiller, Sebastian, Cloonan, Nicole, Lardelli, Rea M., Doggett, Karen, Keightley, Maria-Cristina, Boglev, Yeliz, Trotter, Andrew J., Ng, Annie Y., Wilkins, Simon J., Verkade, Heather, Ober, Elke A., Field, Holly A., Grimmond, Sean M., Lieschke, Graham J., Stainier, Didier Y. R., Heath, Joan K.

“…Minor class or U12-type splicing is a highly conserved process required to remove a minute fraction of introns from human pre-mRNAs. Defects in this splicing…”
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Development of the liver: Insights into organ and tissue morphogenesis by Ober, Elke A., Lemaigre, Frédéric P.

“…Recent development of improved tools and methods to analyse tissues at the three-dimensional level has expanded our capacity to investigate morphogenesis of…”
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Foregut organ progenitors and their niche display distinct viscoelastic properties in vivo during early morphogenesis stages by Dzementsei, Aliaksandr, Barooji, Younes F., Ober, Elke A., Oddershede, Lene B.

“…Material properties of living matter play an important role for biological function and development. Yet, quantification of material properties of internal…”
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Ssrp1a controls organogenesis by promoting cell cycle progression and RNA synthesis by Koltowska, Katarzyna, Apitz, Holger, Stamataki, Despina, Hirst, Elizabeth M A, Verkade, Heather, Salecker, Iris, Ober, Elke A

“…Tightly controlled DNA replication and RNA transcription are essential for differentiation and tissue growth in multicellular organisms. Histone chaperones,…”
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Loss of eyes in zebrafish caused by mutation of chokh/rx3 by Loosli, Felix, Staub, Wendy, Finger-Baier, Karin C, Ober, Elke A, Verkade, Heather, Wittbrodt, Joachim, Baier, Herwig

“…The vertebrate eye forms by specification of the retina anlage and subsequent morphogenesis of the optic vesicles, from which the neural retina differentiates…”
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Non-conventional protrusions: the diversity of cell interactions at short and long distance by Caviglia, Sara, Ober, Elke A

“…Cells use different means to communicate within and between tissues and thereby coordinate their behaviours. Following the initial observations of enigmatic…”
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Making It New Again: Insight Into Liver Development, Regeneration, and Disease From Zebrafish Research by Wang, Shuang, Miller, Sophie R, Ober, Elke A, Sadler, Kirsten C

“…The adult liver of most vertebrates is predominantly comprised of hepatocytes. However, these cells must work in concert with biliary, stellate, vascular, and…”
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Vegfc is required for vascular development and endoderm morphogenesis in zebrafish by Ober, Elke A, Olofsson, Birgitta, Mäkinen, Taija, Jin, Suk-Won, Shoji, Wataru, Koh, Gou Young, Alitalo, Kari, Stainier, Didier Y R

“…During embryogenesis, complex morphogenetic events lead endodermal cells to coalesce at the midline and form the primitive gut tube and associated organs…”
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Genome editing using FACS enrichment of nuclease-expressing cells and indel detection by amplicon analysis by Lonowski, Lindsey A, Narimatsu, Yoshiki, Riaz, Anjum, Delay, Catherine E, Yang, Zhang, Niola, Francesco, Duda, Katarzyna, Ober, Elke A, Clausen, Henrik, Wandall, Hans H, Hansen, Steen H, Bennett, Eric P, Frödin, Morten

“…This protocol provides a pipeline for increasing and evaluating the efficiency of genome editing by ZFNs, TALENs or CRISPR–Cas9 that includes enrichment of…”
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