Search Results - "Obaydo, Reem H."
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Spider diagram and sustainability evaluation of UV-methods strategy for quantification of aspirin and sildenafil citrate in the presence of salicylic acid in their bulk and formulation
Published in Heliyon (01-04-2023)“…The cutting-edge combination of aspirin (ASA) and sildenafil citrate (SIC) has been presented as a suggested dosage form for the treatment of thin endometrium…”
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Fingerprint Spectrophotometric Methods for the Determination of Co-Formulated Otic Solution of Ciprofloxacin and Fluocinolone Acetonide in Their Challengeable Ratio
Published in Journal of analytical methods in chemistry (2019)“…Six spectrophotometric methods were developed to determine a new single-dose otic solution known as “Otovel®,” which consists of two components: the major one…”
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Erratum to “Spider diagram and sustainability evaluation of UV-methods strategy for quantification of aspirin and sildenafil citrate in the presence of salicylic acid in their bulk and formulation” [Heliyon 9(4) (April 2023) e15260]
Published in Heliyon (01-05-2023)“…[This corrects the article DOI: 10.1016/j.heliyon.2023.e15260.]…”
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Sustainable chromatographic quantitation of multi-antihypertensive medications: application on diverse combinations containing hydrochlorothiazide along with LC–MS/MS profiling of potential impurities: greenness and whiteness evaluation
Published in BMC chemistry (19-08-2023)“…Cardiovascular disorders are among the leading causes of death worldwide, especially hypertension, a silent killer syndrome requiring multiple drug therapy for…”
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Ultraviolet spectrophotometric methods for the determination of the minor component presented in fixed-dose pharmaceutical combinations through the last two decades (2000–2020)
Published in Future journal of pharmaceutical sciences (12-02-2021)“…Background The pharmaceutical industry and the National Regulatory Authorities are now focusing on the quantification of multi-component drugs for quality…”
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Ziziphus spina-christi Leaf-Derived Carbon Dots as a Fluorescence Nanosensor to Evaluate Rifaximin Antibacterial via Inner Filter Effect: Greenness and Whiteness Studies
Published in Chemosensors (03-05-2023)“…Rifaximin (RFX) is a non-absorbable antibiotic with broad-spectrum efficacy. It treats travelers’ diarrhea, irritable bowel syndrome, non-systematic bacterial…”
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New spectral resolution techniques for resolving and determining the components in binary fixed-dose combinations
Published in Heliyon (01-10-2019)“…Four spectrophotometric approaches were performed to determine a binary combination of Phenazone and Benzocaine in pure powder form and in pharmaceutical…”
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Spectrophotometric strategies for the analysis of binary combinations with minor component based on isoabsorptive point's leveling effect: An application on ciprofloxacin and fluocinolone acetonide in their recently delivered co-formulation
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (05-08-2019)“…Comparative study of the spectrophotometric strategies utilizing the isoabsorptive point present in overlapped absorption spectra of ciprofloxacin and…”
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ChlorTox scale assessment, greenness, and whiteness evaluation of selective spectrophotometric analysis of dimenhydrinate and cinnarizine
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (15-11-2024)“…[Display omitted] •Novel UV- spectrophotometric methods for simultaneous analysis of DMH and CIN in the presence of their toxic impurities BZP and DPP,…”
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Nano-scale multi-spectroscopic analysis of the anti-fibromyalgia drug pregabalin based on dihydropyridine ring formation with sustainability and whiteness evaluation
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (15-01-2025)“…[Display omitted] •Multiple-spectroscopic assay of the non-chromophoric zwitterionic drug pregabalin.•Employing Hantzsch’s one-pot cyclization reaction in…”
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Environmentally sustainable computationally spectrophotometric resolution strategy for analysis single-tablet regimens of antihypertension with overlapped spectra
Published in Talanta open (01-08-2023)“…•Analytical fingerprint technique is being developed to recover the parent spectral signal from complex medication mixtures.•Greenness evaluation using the…”
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Eco-friendly chemometric analysis: Sustainable quantification of five pharmaceutical compounds in bulk, tablets, and spiked human plasma
Published in Results in Chemistry (01-10-2024)“…[Display omitted] The development of sustainable chemometric methodologies is crucial in pharmaceutical analysis to ensure accurate chemical quantification…”
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Validated spectrofluorimetric method for the determination of netilmicin based on its interaction with o‐phthalaldehyde/mercaptoethanol: Evaluation of the method's greenness
Published in Luminescence (Chichester, England) (01-02-2024)“…In this study, netilmicin (NTM) was selectively assessed in its dosage forms after a facile derivatization reaction. The proposed approach was based on the…”
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Spider chart and whiteness assessment of synergistic spectrophotometric strategy for quantification of triple combination recommended in seasonal influenza – Detection of spurious drug
Published in Sustainable chemistry and pharmacy (01-05-2023)“…Trimed Flu® Tablets are commonly specified to treat the cold, cough, and fever in clinical management protocol for seasonal influenza. These tablets comprise…”
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Guidelines for accurate application of green and white analytical concepts: Merits Versus demerits with insights of significant milestones of assessment tools applied for antiviral drugs
Published in Microchemical journal (01-04-2024)“…[Display omitted] •Reviewing milestones of analytical assessment tools, and presenting timeline progress for their application for analysis of antiviral…”
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Chemometric-assisted spectrophotometric methods for simultaneous drug determination in new Helicobacter pylori treatment regimens - Environmental sustainability assessment
Published in Sustainable chemistry and pharmacy (01-12-2024)“…The recent FDA approval of VOQUEZNA™ TRIPLE PAK™ 7-day therapy, which includes vonoprazan (VON), amoxicillin (AMO), and clarithromycin (CLA), marks a…”
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Application of advanced environmentally benign assessment tools in determining ternary cardiovascular drug combination by RP-HPLC with analytical quality by design: Application to stability indicating method evaluation
Published in Sustainable chemistry and pharmacy (01-10-2023)“…Assessing any analytical method is becoming an important aspect for showcasing its importance and impact on the environment. The present work aimed to showcase…”
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Whiteness and greenness assessment with efficacy evaluation of two UPLC systems applied for the quantification of cinnarizine and dimenhydrinate along with their toxic impurities
Published in Sustainable chemistry and pharmacy (01-12-2023)“…Fixed-dose combination of cinnarizine (CIN) and dimenhydrinate (DMH) is an effective therapy for patients diagnosed for having central and/or peripheral…”
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Propylene carbonate as an ecofriendly solvent: Stability studies of Ripretinib in RPHPLC and sustainable evaluation using advanced tools
Published in Sustainable chemistry and pharmacy (01-02-2024)“…Ripretinib (RPB) is a U.S. Food and Drug Administration approved drug for the treatment of advanced gastrointestinal stromal tumour. According to literature…”
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Factorial design-aided derivatization-free fluorimetric ultrasensitive assay of vonoprazan with application in uniformity of dosage units and plasma samples analysis: Comprehensive and comparative greenness and whiteness assessment
Published in Microchemical journal (01-10-2024)“…[Display omitted] •A novel factorial design-optimized spectrofluorimetric method for vonoprazan without pre-derivatization.•Complex formation between…”
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