Search Results - "Obara, Masanobu"

Microhomology-mediated end-joining-dependent integration of donor DNA in cells and animals using TALENs and CRISPR/Cas9 by Nakade, Shota, Tsubota, Takuya, Sakane, Yuto, Kume, Satoshi, Sakamoto, Naoaki, Obara, Masanobu, Daimon, Takaaki, Sezutsu, Hideki, Yamamoto, Takashi, Sakuma, Tetsushi, Suzuki, Ken-ichi T.

“…Genome engineering using programmable nucleases enables homologous recombination (HR)-mediated gene knock-in. However, the labour used to construct targeting…”
Get full text

third type III module of human fibronectin mediates cell adhesion and migration by Obara, Masanobu, Sakuma, Tetsushi, Fujikawa, Kazuyuki

“…Fibronectin (FN) is a major extracellular matrix protein involved in various biological events. This study demonstrated that the third FN type III repeat…”
Get full text

Identification of vitamin A-free cells in a stellate cell-enriched fraction of normal rat liver as myofibroblasts by Ogawa, Tomohiro, Tateno, Chise, Asahina, Kinji, Fujii, Hideki, Kawada, Norifumi, Obara, Masanobu, Yoshizato, Katsutoshi

“…Myofibroblasts (MFs) as well as hepatic stellate cells (HSCs) are known to be involved in liver fibrogenesis. Quiescent HSCs (qHSCs) in culture have been…”
Get full text

Identification of the Ligand Binding Site for the Integrin α9β1 in the Third Fibronectin Type III Repeat of Tenascin-C by Yokosaki, Yasuyuki, Matsuura, Nariaki, Higashiyama, Shigeki, Murakami, Isao, Obara, Masanobu, Yamakido, Michio, Shigeto, Norikazu, Chen, John, Sheppard, Dean

Get full text

Unique expression patterns of matrix metalloproteinases in regenerating newt limbs by Kato, Tomoko, Miyazaki, Koyomi, Shimizu‐Nishikawa, Keiko, Koshiba, Kazuko, Obara, Masanobu, Mishima, Hiromu K., Yoshizato, Katsutoshi

“…The process of regeneration of urodele limbs includes a drastic remodeling of extracellular matrices (ECMs) that is induced by matrix metalloproteinases (MMPs)…”
Get full text

Typing of hepatic nonparenchymal cells using fibulin-2 and cytoglobin/STAP as liver fibrogenesis-related markers by Tateaki, Yuko, Ogawa, Tomohiro, Kawada, Norifumi, Kohashi, Toshihiko, Arihiro, Koji, Tateno, Chise, Obara, Masanobu, Yoshizato, Katsutoshi

“…Fibulin-2 and cytoglobin/stellate cell activation-associated protein (Cygb/STAP) are considered to be markers of hepatic myofibroblasts (MFs) and stellate…”
Get full text

Characterization of histone lysine-specific demethylase in relation to thyroid hormone-regulated anuran metamorphosis by Chen, Wen, Obara, Masanobu, Ishida, Yuji, Suzuki, Ken-ichi, Yoshizato, Katsutoshi

“…The thyroid hormone receptor (THR) is a member of the nuclear transcription factor and plays a central role in regulating anuran metamorphosis. Previous…”
Get full text

Metamorphosis‐dependent transcriptional regulation of xak‐c, a novel Xenopus type I keratin gene by Watanabe, Yusuke, Tanaka, Rumi, Kobayashi, Hisao, Utoh, Rie, Suzuki, Ken‐Ichi, Obara, Masanobu, Yoshizato, Katsutoshi

“…Anuran larvae transform their epidermis to the adult counterpart during metamorphosis. The major event of this process is the proliferation of larval epidermal…”
Get full text

Cloning and characterization of the full length cDNA encoding α2 type I collagen of bullfrog Rana catesbeiana by Asahina, Kinji, Oofusa, Ken, Obara, Masanobu, Yoshizato, Katsutoshi

“…The present study determined nucleotide sequences of the full-length cDNA of α2 chain of bullfrog type I collagen. Hybridization of a bullfrog cDNA library…”
Get full text

Developmentally and regionally regulated participation of epidermal cells in the formation of collagen lamella of anuran tadpole skin by Utoh, Rie, Asahina, Kinji, Suzuki, Kenichi, Kotani, Kaori, Obara, Masanobu, Yoshizato, Katsutoshi

“…We investigated the cellular mechanism of formation of subepidermal thick bundles of collagen (collagen lamella) during larval development of the bullfrog,…”
Get full text

Characterization of human stellate cell activation-associated protein and its expression in human liver by Asahina, Kinji, Kawada, Norifumi, Kristensen, Dan Bach, Nakatani, Kazuki, Seki, Shuichi, Shiokawa, Miho, Tateno, Chise, Obara, Masanobu, Yoshizato, Katsutoshi

“…This study cloned cDNA of human homologue (hSTAP) of rat stellate cell activation-associated protein (rSTAP). hSTAP gene is on chromosome 17q and is composed…”
Get full text

Vector-swapping strategy with an exonuclease in cloning and high expression of small PCR products by Obara, M, Yoshizato, K

Get full text

Production of a non-triple helical collagen α chain in transgenic silkworms and its evaluation as a gelatin substitute for cell culture by Adachi, Takahiro, Wang, Xiaobiao, Murata, Tomoko, Obara, Masanobu, Akutsu, Hidenori, Machida, Masakazu, Umezawa, Akirihiro, Tomita, Masahiro

“…We generated transgenic silkworms that synthesized human type I collagen α1 chain [α1(I) chain] in the middle silk glands and secreted it into cocoons. The…”
Get full text

The interaction of cellular fibronectin with collagen during fibroblast-mediated contraction of collagen gels by Yoshizato, K, Tsukahara, M, Oki, T, Hayashi, M, Obara, M, Morpho, Y

“…In the first instance highly hydrated collagen gels contract to dense and compact gels when populated by fibroblasts. We previously reported the involvement of…”
Get more information

Role of fibronectin in adhesion, migration, and metastasis by Humphries, M J, Obara, M, Olden, K, Yamada, K M

Get more information

Analysis of N-myc amplification in relation to disease stage and histologic types in human neuroblastomas by Tsuda, T, Obara, M, Hirano, H, Gotoh, S, Kubomura, S, Higashi, K, Kuroiwa, A, Nakagawara, A, Nagahara, N, Shimizu, K

“…Both untreated and treated primary neuroblastomas from 52 patients were analyzed to determine the correlation between the amplification of N-myc oncogene and…”
Get more information

Homeolog-specific targeted mutagenesis in Xenopus laevis using TALENs by Nakade, Shota, Sakuma, Tetsushi, Sakane, Yuto, Hara, Yoshihiro, Kurabayashi, Atsushi, Kashiwagi, Keiko, Kashiwagi, Akihiko, Yamamoto, Takashi, Obara, Masanobu

“…Transcription activator-like effector nucleases (TALENs) have previously been used for targeted genome editing in various organisms including Xenopus laevis…”
Get full text

Gene expression and tissue distribution of cytoglobin and myoglobin in the Amphibia and Reptilia: Possible compensation of myoglobin with cytoglobin in skeletal muscle cells of anurans that lack the myoglobin gene by Xi, Yang, Obara, Masanobu, Ishida, Yuji, Ikeda, Shino, Yoshizato, Katsutoshi

“…Cytoglobin (Cygb), a recently discovered vertebrate cytoplasmic heme-binding globin, is considered to be in a clade with vertebrate myoglobin (Mb), which is…”
Get full text

Production of a non-triple helical collagen [alpha] chain in transgenic silkworms and its evaluation as a gelatin substitute for cell culture by Adachi, Takahiro, Wang, Xiaobiao, Murata, Tomoko, Obara, Masanobu, Akutsu, Hidenori, Machida, Masakazu, Umezawa, Akirihiro, Tomita, Masahiro

“…We generated transgenic silkworms that synthesized human type I collagen α1 chain [α1(I) chain] in the middle silk glands and secreted it into cocoons. The…”
Get full text

Hydrocortisone-induced enhancement of expression and changes in methylation of pepsinogen genes in stomach mucosa of the developing rat by Ichinose, M, Miki, K, Tatematsu, M, Furihata, C, Matsushima, M, Ichihara, Y, Tanji, M, Konishi, T, Obara, M, Inoue, H

“…Administration of hydrocortisone to infant rats caused a precocious increase in levels of mucosal pepsinogen and its mRNA together with morphological…”
Get more information