Search Results - "Obaid, Ahmad A."
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1
Flavonoids as Promising Neuroprotectants and Their Therapeutic Potential against Alzheimer’s Disease
Published in Oxidative medicine and cellular longevity (28-08-2022)“…Alzheimer’s disease (AD) is one of the serious and progressive neurodegenerative disorders in the elderly worldwide. Various genetic, environmental, and…”
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2
Appraisal of the Antioxidant Activity, Polyphenolic Content, and Characterization of Selected Himalayan Herbs: Anti-Proliferative Potential in HepG2 Cells
Published in Molecules (Basel, Switzerland) (01-12-2022)“…Natural antioxidants derived from plants have played a vital role in preventing a wide range of human chronic conditions and provide novel bioactive leads for…”
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3
Identification of miRNA–mRNA–TFs regulatory network and crucial pathways involved in asthma through advanced systems biology approaches
Published in PloS one (20-10-2022)“…Asthma is a life-threatening and chronic inflammatory lung disease that is posing a true global health challenge. The genetic basis of the disease is fairly…”
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4
Antibacterial Effects of Commiphora gileadensis Methanolic Extract on Wound Healing
Published in Molecules (Basel, Switzerland) (21-05-2022)“…Commiphora gileadensis (CG) is a small tree distributed throughout the Middle East. It was traditionally used in perfumes in countries in this area. In Saudi…”
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5
Key Disease-Related Genes and Immune Cell Infiltration Landscape in Inflammatory Bowel Disease: A Bioinformatics Investigation
Published in International journal of molecular sciences (01-09-2024)“…Inflammatory Bowel Diseases (IBD), which encompass ulcerative colitis (UC) and Crohn's disease (CD), are characterized by chronic inflammation and tissue…”
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6
Improved Glycaemic Control and Nephroprotective Effects of Empagliflozin and Paricalcitol Co-Therapy in Mice with Type 2 Diabetes Mellitus
Published in International journal of molecular sciences (12-12-2023)“…Herein, we measured the antidiabetic and nephroprotective effects of the sodium-glucose cotransporter-2 inhibitor (empagliflozin; SGLT2i) and synthetic active…”
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7
Bilateral Glaucoma as Possible Additional Feature for PGAP3-Associated Hyperphosphatasia
Published in Case reports in genetics (23-03-2024)“…Hyperphosphatasia with mental disorder (HPMRS) is a rare autosomal recessive disease caused by gene mutations in enzymes involved in the synthesis and…”
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8
Influence of the Gut Microbiota on the Development of Neurodegenerative Diseases
Published in Mediators of inflammation (30-09-2022)“…Neurodegenerative disorders are marked by neuronal death over time, causing a variety of cognitive and motor dysfunctions. Protein misfolding,…”
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9
Metabolite Alterations in Autoimmune Diseases: A Systematic Review of Metabolomics Studies
Published in Metabolites (01-09-2023)“…Autoimmune diseases, characterized by the immune system’s loss of self-tolerance, lack definitive diagnostic tests, necessitating the search for reliable…”
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10
Therapeutic Antiaging Strategies
Published in Biomedicines (01-10-2022)“…Aging constitutes progressive physiological changes in an organism. These changes alter the normal biological functions, such as the ability to manage…”
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11
Copper-mediated β-amyloid toxicity and its chelation therapy in Alzheimer's disease
Published in Metallomics (13-06-2022)“…Abstract The link between bio-metals, Alzheimer's disease (AD), and its associated protein, amyloid-β (Aβ), is very complex and one of the most studied aspects…”
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12
Vitamin D and calcium co-therapy mitigates pre-established cadmium nephropathy by regulating renal calcium homeostatic molecules and improving anti-oxidative and anti-inflammatory activities in rat
Published in Journal of trace elements in medicine and biology (01-09-2023)“…Cadmium (Cd) is a major environmental pollutant and chronic toxicity could induce nephropathy by increasing renal oxidative stress and inflammation. Although…”
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13
Enhanced hepatoprotective effects of empagliflozin and vitamin D dual therapy against metabolic dysfunction‐associated steatohepatitis in mice by boosted modulation of metabolic, oxidative stress, and inflammatory pathways
Published in International journal of experimental pathology (01-12-2024)“…Although single treatment with sodium‐glucose cotransporter‐2 inhibitors (SGLT2i) or vitamin D3 (VD3) inhibited metabolic dysfunction‐associated…”
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14
Protection of Phytoextracts against Rotenone-Induced Organismal Toxicities in Drosophila melanogaster via the Attenuation of ROS Generation
Published in Applied sciences (01-10-2022)“…Nutraceuticals play an essential role in the reduction in free radical generation in cells. A similar idea was used in the present study to determine the…”
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15
Relationship of Vitamin-D Deficiency with Kidney Disease in Patients with Type-2 Diabetes Mellitus (T2DM) in the Makkah Region: A Cross-Sectional Study
Published in Diabetes, metabolic syndrome and obesity (01-01-2024)“…Vitamin D deficiency is linked with type 2 diabetes mellitus (T2DM) and the occurrence of complications in patients with type 2 diabetes mellitus. None of the…”
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16
A Cross-Sectional Study of Anesthesia Safety in Wad Medani, Sudan: A Pre-war Status Indicating a Post-war Crisis
Published in Curēus (Palo Alto, CA) (22-03-2024)“…As the surgical burden grows, increasing patient safety during anesthesia and surgery becomes a major global public health priority. Anesthesia can be safely…”
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17
Bilateral Glaucoma as Possible Additional Feature for PGAP3 -Associated Hyperphosphatasia
Published in Case reports in genetics (2024)“…Hyperphosphatasia with mental disorder (HPMRS) is a rare autosomal recessive disease caused by gene mutations in enzymes involved in the synthesis and…”
Get full text
Journal Article -
18
Relationship of Vitamin-D Deficiency with Kidney Disease in Patients with Type-2 Diabetes Mellitus
Published in Diabetes, metabolic syndrome and obesity (31-01-2024)“…Aim: Vitamin D deficiency is linked with type 2 diabetes mellitus (T2DM) and the occurrence of complications in patients with type 2 diabetes mellitus. None of…”
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Journal Article -
19
Identification of miRNA–mRNA–TFs regulatory network and crucial pathways involved in asthma through advanced systems biology approaches
Published in PloS one (01-01-2022)“…Asthma is a life-threatening and chronic inflammatory lung disease that is posing a true global health challenge. The genetic basis of the disease is fairly…”
Get full text
Journal Article -
20
Development of Human and Rat Ptc Monolayers as in Vitro Models of Nephrotoxicity
Published 01-01-2019“…Nephrotoxicity is a serious side effect of many drugs due to the kidney being one of the major sites for their excretion. In vitro models of nephrotoxicity are…”
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Dissertation