Search Results - "Oba, Shigeyoshi"

Therapeutic Effects of Mesenchymal Stem Cell-Derived Exosomes in Cardiovascular Disease by Suzuki, Etsu, Fujita, Daishi, Takahashi, Masao, Oba, Shigeyoshi, Nishimatsu, Hiroaki

“…Mesenchymal stem cells (MSCs) are multipotent stem cells that reside in various organs. They have the capacity to differentiate into various cell types,…”
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Salt causes aging-associated hypertension via vascular Wnt5a under Klotho deficiency by Kawarazaki, Wakako, Mizuno, Risuke, Nishimoto, Mitsuhiro, Ayuzawa, Nobuhiro, Hirohama, Daigoro, Ueda, Kohei, Kawakami-Mori, Fumiko, Oba, Shigeyoshi, Marumo, Takeshi, Fujita, Toshiro

“…Aging is associated with a high prevalence of hypertension due to elevated susceptibility of BP to dietary salt, but its mechanism is unknown. Serum levels of…”
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Mineralocorticoid receptor blockade suppresses dietary salt-induced ACEI/ARB-resistant albuminuria in non-diabetic hypertension: a sub-analysis of evaluate study by Nishimoto, Mitsuhiro, Ohtsu, Hiroshi, Marumo, Takeshi, Kawarazaki, Wakako, Ayuzawa, Nobuhiro, Ueda, Kohei, Hirohama, Daigoro, Kawakami-Mori, Fumiko, Shibata, Shigeru, Nagase, Miki, Isshiki, Masashi, Oba, Shigeyoshi, Shimosawa, Tatsuo, Fujita, Toshiro

“…Excessive dietary salt intake can counteract the renoprotective effects of renin-angiotensin system (RAS) blockade in hypertensive patients with chronic kidney…”
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Rac1 deficiency impairs postnatal development of the renal papilla by Ayuzawa, Nobuhiro, Nishimoto, Mitsuhiro, Kawarazaki, Wakako, Oba, Shigeyoshi, Marumo, Takeshi, Aiba, Atsu, Fujita, Toshiro

“…Development of the renal medulla continues after birth to form mature renal papilla and obtain urine-concentrating ability. Here, we found that a small GTPase,…”
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miR-200b precursor can ameliorate renal tubulointerstitial fibrosis by Oba, Shigeyoshi, Kumano, Shintaro, Suzuki, Etsu, Nishimatsu, Hiroaki, Takahashi, Masao, Takamori, Hajime, Kasuya, Masatoshi, Ogawa, Yousuke, Sato, Kenichiro, Kimura, Kenjiro, Homma, Yukio, Hirata, Yasunobu, Fujita, Toshiro

“…Members of the miR-200 family of micro RNAs (miRNAs) have been shown to inhibit epithelial-mesenchymal transition (EMT). EMT of tubular epithelial cells is the…”
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Histone methylation and demethylation are implicated in the transient and sustained activation of the interleukin-1β gene in murine macrophages by Imuta, Hiroyuki, Fujita, Daishi, Oba, Shigeyoshi, Kiyosue, Arihiro, Nishimatsu, Hiroaki, Yudo, Kazuo, Suzuki, Etsu

“…Macrophages play a crucial role in the development of atherosclerosis. To explore the mechanism by which macrophages attain a proinflammatory phenotype for a…”
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Aberrant DNA methylation of Tgfb1 in diabetic kidney mesangial cells by Oba, Shigeyoshi, Ayuzawa, Nobuhiro, Nishimoto, Mitsuhiro, Kawarazaki, Wakako, Ueda, Kohei, Hirohama, Daigoro, Kawakami-Mori, Fumiko, Shimosawa, Tatsuo, Marumo, Takeshi, Fujita, Toshiro

“…Epigenetic modulation may underlie the progression of diabetic nephropathy (DN). Involvement of TGFB1 in mesangial fibrosis of DN led us to hypothesize that…”
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Adipose tissue-derived stem cells as a therapeutic tool for cardiovascular disease by Suzuki, Etsu, Fujita, Daishi, Takahashi, Masao, Oba, Shigeyoshi, Nishimatsu, Hiroaki

“…Adipose tissue-deried stem cells( ADSCs) are adult stem cells that can be easily harvested from subcutaneous adipose tissue. Many studies have demonstrated…”
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Endogenous Interleukin-1β Is Implicated in Intraplaque Hemorrhage in Apolipoprotein E Gene Null Mice by Suzuki, Etsu, Imuta, Hiroyuki, Fujita, Daishi, Takahashi, Masao, Oba, Shigeyoshi, Kiyosue, Arihiro, Nishimatsu, Hiroaki

“…Background:Intraplaque hemorrhage (IPH) has been implicated in plaque instability and rupture in atherosclerotic lesions, although the mechanisms by which IPH…”
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miR-133 regulates Evi1 expression in AML cells as a potential therapeutic target by Yamamoto, Haruna, Lu, Jun, Oba, Shigeyoshi, Kawamata, Toyotaka, Yoshimi, Akihide, Kurosaki, Natsumi, Yokoyama, Kazuaki, Matsushita, Hiromichi, Kurokawa, Mineo, Tojo, Arinobu, Ando, Kiyoshi, Morishita, Kazuhiro, Katagiri, Koko, Kotani, Ai

“…The Ecotropic viral integration site 1 (Evi1) is a zinc finger transcription factor, which is located on chromosome 3q26, over-expression in some acute myeloid…”
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Oncogene- and Oxidative Stress-Induced Cellular Senescence Shows Distinct Expression Patterns of Proinflammatory Cytokines in Vascular Endothelial Cells by Nishimatsu, Hiroaki, Oba, Shigeyoshi, Takahashi, Masao, Suzuki, Etsu

“…Senescent cells are metabolically active and produce a variety of proinflammatory cytokines. It was previously reported that atherosclerotic plaques contain…”
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Aberrant DNA methylation of hypothalamic angiotensin receptor in prenatal programmed hypertension by Kawakami-Mori, Fumiko, Nishimoto, Mitsuhiro, Reheman, Latapati, Kawarazaki, Wakako, Ayuzawa, Nobuhiro, Ueda, Kohei, Hirohama, Daigoro, Kohno, Daisuke, Oba, Shigeyoshi, Shimosawa, Tatsuo, Marumo, Takeshi, Fujita, Toshiro

“…Maternal malnutrition, which causes prenatal exposure to excessive glucocorticoid, induces adverse metabolic programming, leading to hypertension in offspring…”
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Adipose tissue-derived stem cells inhibit neointimal formation in a paracrine fashion in rat femoral artery by Takahashi, Masao, Suzuki, Etsu, Oba, Shigeyoshi, Nishimatsu, Hiroaki, Kimura, Kenjiro, Nagano, Tetsuo, Nagai, Ryozo, Hirata, Yasunobu

“…Subcutaneous adipose tissue contains a lot of stem cells [adipose-derived stem cells (ASCs)] that can differentiate into a variety of cell lineages. In this…”
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Renoprotective effect of erythropoietin in ischemia/reperfusion injury: Possible roles of the Akt/endothelial nitric oxide synthase-dependent pathway by Oba, Shigeyoshi, Suzuki, Etsu, Nishimatsu, Hiroaki, Kumano, Shintaro, Hosoda, Chihiro, Homma, Yukio, Hirata, Yasunobu

“…Objectives:  It has been reported that erythropoietin protects the kidneys from ischemia/reperfusion injury. In the present study, we examined the role of Akt…”
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Adipose-Derived Stem Cells Stimulate Reendothelialization in Stented Rat Abdominal Aorta by Sato, Tomohiko, Takahashi, Masao, Fujita, Daishi, Oba, Shigeyoshi, Nishimatsu, Hiroaki, Nagano, Tetsuo, Suzuki, Etsu

“…Background: Although drug-eluting stents (DES) have been widely used for the treatment of coronary artery disease, they potentially increase the risk of late…”
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Angiopoietin-1 Mediates Adipose Tissue-Derived Stem Cell-Induced Inhibition of Neointimal Formation in Rat Femoral Artery by Takahashi, Masao, Suzuki, Etsu, Kumano, Shintaro, Oba, Shigeyoshi, Sato, Tomohiko, Nishimatsu, Hiroaki, Kimura, Kenjiro, Nagano, Tetsuo, Hirata, Yasunobu

“…Background: Adipose tissue-derived stem cells (ASC) produce a variety of cytokines that potentially mediate the proangiogenic and antiapoptotic effects of the…”
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Stem cell-derived exosomes as a therapeutic tool for cardiovascular disease by Suzuki, Etsu, Fujita, Daishi, Takahashi, Masao, Oba, Shigeyoshi, Nishimatsu, Hiroaki

“…Mesenchymal stem cells (MSCs) have been used to treat patients suffering from acute myocardial infarction (AMI) and subsequent heart failure. Although it was…”
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Adult stem cells as a tool for kidney regeneration by Suzuki, Etsu, Fujita, Daishi, Takahashi, Masao, Oba, Shigeyoshi, Nishimatsu, Hiroaki

“…Kidney regeneration is a challenging but promising strategy aimed at reducing the progression to end-stage renal disease(ESRD) and improving the quality of…”
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Blockade of endogenous cytokines mitigates neointimal formation in obese Zucker rats by TAKEDA, Ryo, SUZUKI, Etsu, SATONAKA, Hiroshi, OBA, Shigeyoshi, NISHIMATSU, Hiroaki, OMATA, Masao, FUJITA, Toshiro, NAGAI, Ryozo, HIRATA, Yasunobu

“…It is well known that diabetes mellitus is a major risk factor for vascular diseases such as atherosclerosis and restenosis after angioplasty. It has become…”
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Blockade of Endogenous Proinflammatory Cytokines Ameliorates Endothelial Dysfunction in Obese Zucker Rats by Nishimatsu, Hiroaki, Suzuki, Etsu, Takeda, Ryo, Takahashi, Masao, Oba, Shigeyoshi, Kimura, Kenjiro, Nagano, Tetsuo, Hirata, Yasunobu

“…To study the role of endogenous proinflammatory cytokines in endothelial dysfunction in diabetes, we administered semapimod, an inhibitor of proinflammatory…”
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