Search Results - "Oba, Kazuhito"

Suprabasin-derived bioactive peptides identified by plasma peptidomics by Taguchi, Tomomi, Kodera, Yoshio, Oba, Kazuhito, Saito, Tatsuya, Nakagawa, Yuzuru, Kawashima, Yusuke, Shichiri, Masayoshi

“…Identification of low-abundance, low-molecular-weight native peptides using non-tryptic plasma has long remained an unmet challenge, leaving potential…”
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Use of Dementia Assessment Sheet for Community‐based Integrated Care System 8‐items (DASC‐8) for the screening of frailty and components of comprehensive geriatric assessment by Toyoshima, Kenji, Araki, Atsushi, Tamura, Yoshiaki, Ishikawa, Joji, Kodera, Remi, Oba, Kazuhito, Chiba, Yuko, Awata, Shuichi

“…Aim We examined whether the Dementia Assessment Sheet for Community‐based Integrated Care System 8‐items (DASC‐8) is useful for screening frailty and as a…”
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Dynapenic abdominal obesity is associated with mild cognitive impairment in patients with cardiometabolic disease: a cross-sectional study by Oba, Kazuhito, Tamura, Yoshiaki, Ishikawa, Joji, Suzuki, Hiroyuki, Fujiwara, Yoshinori, Tachibana, Aya, Kodera, Remi, Toyoshima, Kenji, Chiba, Yuko, Araki, Atsushi

“…Dementia is an important health issue for older people and requires early intervention in the mild cognitive impairment (MCI) stage to manage risk factors…”
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Hypopituitarism with secondary adrenocortical insufficiency and arginine vasopressin deficiency due to hypophysitis after COVID-19 vaccination: a case report by Watanabe, So, Tamura, Yoshiaki, Oba, Kazuhito, Kitayama, Saori, Sato, Motoya, Kodera, Remi, Toyoshima, Kenji, Chiba, Yuko, Araki, Atsushi

“…Although vaccination against coronavirus disease (COVID-19) has several side effects, hypopituitarism due to hypophysitis has rarely been reported. An…”
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Suppressed recruitment of alternatively activated macrophages reduces TGF-β1 and impairs wound healing in streptozotocin-induced diabetic mice by Okizaki, Shin-ichiro, Ito, Yoshiya, Hosono, Kanako, Oba, Kazuhito, Ohkubo, Hirotoki, Amano, Hideki, Shichiri, Masayoshi, Majima, Masataka

“…Abstract Background Diabetes mellitus inhibits wound-induced angiogenesis, impairing the wound healing process and leading to the development of chronic…”
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Associations between sarcopenia and white matter alterations in older adults with diabetes mellitus: A diffusion tensor imaging study by Tamura, Yoshiaki, Shimoji, Keigo, Ishikawa, Joji, Tachibana, Aya, Kodera, Remi, Oba, Kazuhito, Toyoshima, Kenji, Chiba, Yuko, Tokumaru, Aya M, Araki, Atsushi

“…Aims/Introduction Older adults with diabetes mellitus are susceptible to sarcopenia. Diffusion tensor imaging studies have also shown that patients with…”
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Serum growth differentiation factor 15 level is associated with muscle strength and lower extremity function in older patients with cardiometabolic disease by Oba, Kazuhito, Ishikawa, Joji, Tamura, Yoshiaki, Fujita, Yasunori, Ito, Masafumi, Iizuka, Ai, Fujiwara, Yoshinori, Kodera, Remi, Toba, Ayumi, Toyoshima, Kenji, Chiba, Yuko, Mori, Seijiro, Tanaka, Masashi, Ito, Hideki, Harada, Kazumasa, Araki, Atsushi

“…Aims Sarcopenia is a serious problem because of its poor prognosis. Growth differentiation factor 15 (GDF15) is associated with mitochondrial dysfunction,…”
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The cross-sectional area of erector spinae muscle and the liver-to-spleen ratio are associated with frailty in older patients with diabetes: a cross-sectional study by Sato, Motoya, Tamura, Yoshiaki, Murao, Yuji, Yorikawa, Fumino, Katsumata, Yuu, Watanabe, So, Zen, Shugo, Kodera, Remi, Oba, Kazuhito, Toyoshima, Kenji, Chiba, Yuko, Araki, Atsushi

“…Older patients with diabetes mellitus are more susceptible to frailty. Although some imaging markers of appendicular skeletal muscle mass obtained using…”
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Coexistence of high visceral fat area and sarcopenia is associated with atherosclerotic markers in old‐old patients with diabetes: A cross‐sectional study by Sato, Motoya, Tamura, Yoshiaki, Murao, Yuji, Yorikawa, Fumino, Katsumata, Yuu, Watanabe, So, Zen, Shugo, Kodera, Remi, Oba, Kazuhito, Toyoshima, Kenji, Chiba, Yuko, Araki, Atsushi

“…ABSTRACT Aims/Introduction To investigate whether sarcopenic obesity is associated with the progression of atherosclerotic lesions in older patients with…”
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Adrenal Insufficiency and Thyrotoxicosis Following Combined Immune Checkpoint Inhibitor Use: A Case Report and Literature Review by Fukushima, Kaoruko, Kitayama, Saori, Sazuka, Manami, Kodera, Remi, Oba, Kazuhito, Toyoshima, Kenji, Chiba, Yuko, Yamamoto, Hiroshi, Araki, Atsushi, Tamura, Yoshiaki

“…Destructive thyroiditis and secondary adrenal insufficiency are major endocrinological immune-related adverse events of immune checkpoint inhibitors (ICIs)…”
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Association between white matter alterations on diffusion tensor imaging and incidence of frailty in older adults with cardiometabolic diseases by Tamura, Yoshiaki, Shimoji, Keigo, Ishikawa, Joji, Murao, Yuji, Yorikawa, Fumino, Kodera, Remi, Oba, Kazuhito, Toyoshima, Kenji, Chiba, Yuko, Tokumaru, Aya M., Araki, Atsushi

“…Diffusion tensor imaging (DTI) can be used for the early detection of abnormal changes in the integrity of cerebral white matter tracts, and we have previously…”
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Subclinical Atherosclerosis, Vascular Risk Factors, and White Matter Alterations in Diffusion Tensor Imaging Findings of Older Adults With Cardiometabolic Diseases by Tamura, Yoshiaki, Shimoji, Keigo, Ishikawa, Joji, Matsuo, Yoshinori, Watanabe, So, Takahashi, Hisae, Zen, Shugo, Tachibana, Aya, Omura, Takuya, Kodera, Remi, Oba, Kazuhito, Toyoshima, Kenji, Chiba, Yuko, Tokumaru, Aya M., Araki, Atsushi

“…White matter abnormalities may reflect cerebral microvessel disease. Diffusion tensor imaging (DTI) can help detect early changes in white matter integrity in…”
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Oldest‐old type 1 diabetes patient receiving insulin pump treatment with positive myeloperoxidase‐antineutrophil cytoplasmic antibody complication: A case report by Omura, Takuya, Tamura, Yoshiaki, Kodera, Remi, Oba, Kazuhito, Toyoshima, Kenji, Chiba, Yuko, Sugihara, Takahiro, Itabashi, Mitsuyo, Shigemoto, Kazuhiro, Araki, Atsushi

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Pancreatic cancer manifesting as Sister Mary Joseph nodule during follow up of a patient with type 2 diabetes mellitus: A case report by Omura, Takuya, Tamura, Yoshiaki, Kodera, Remi, Oba, Kazuhito, Toyoshima, Kenji, Chiba, Yuko, Matsuda, Yoko, Uegaki, Satoko, Kuroiwa, Kojiro, Araki, Atsushi

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Downregulation of the proangiogenic prostaglandin E receptor EP3 and reduced angiogenesis in a mouse model of diabetes mellitus by Oba, Kazuhito, Hosono, Kanako, Amano, Hideki, Okizaki, Shin-ichiro, Ito, Yoshiya, Shichiri, Masayoshi, Majima, Masataka

“…Abstract Vascular complications such as foot ulcers are a hallmark of diabetes mellitus (DM), although the molecular mechanisms that underlie vascular…”
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Primary Aldosteronism Associated with Multiple Adrenocortical Micronodules in a Patient with Renal Cell Carcinoma by Toyoshima, Koichi, Kodera, Remi, Tamura, Yoshiaki, Nagata, Takashi, Yamazaki, Yuto, Sasano, Hironobu, Araki, Atsushi, Tachibana, Aya, Hashimoto, Seiji, Akahoshi, Miho, Aoyama, Rie, Kumakawa, Takeshi, Matsuda, Yoko, Chiba, Yuko, Oba, Kazuhito, Toyoshima, Kenji

“…A 47-year-old woman with a history of diabetes mellitus (DM) and obesity was admitted to our hospital for glucose control. She was detected to have…”
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Risk factor of disability as new certification of long‐term care needs in older Japanese adults with diabetes mellitus: A longitudinal study by Toyoshima, Kenji, Tamura, Yoshiaki, Murao, Yuji, Kodera, Remi, Oba, Kazuhito, Ishikawa, Joji, Chiba, Yuko, Araki, Atsushi

“…Aim This observational longitudinal study aimed to explore the risk factors for disabilities in older Japanese individuals with diabetes at a frailty clinic,…”
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Vascular Endothelial Growth Factor Receptor Type 1 Signaling Prevents Delayed Wound Healing in Diabetes by Attenuating the Production of IL-1β by Recruited Macrophages by Okizaki, Shin-ichiro, Ito, Yoshiya, Hosono, Kanako, Oba, Kazuhito, Ohkubo, Hirotoki, Kojo, Ken, Nishizawa, Nobuyuki, Shibuya, Masabumi, Shichiri, Masayoshi, Majima, Masataka

“…The persistence of proinflammatory macrophages, which are recruited to the granulation tissue, impairs the healing of diabetic wounds. Herein, we examined the…”
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Serum Growth Differentiation Factor 15 Levels Predict the Incidence of Frailty among Patients with Cardiometabolic Diseases by Oba, Kazuhito, Ishikawa, Joji, Tamura, Yoshiaki, Fujita, Yasunori, Ito, Masafumi, Iizuka, Ai, Fujiwara, Yoshinori, Kodera, Remi, Toyoshima, Kenji, Chiba, Yuko, Tanaka, Masashi, Araki, Atsushi

“…Frailty is a crucial health issue among older adults. Growth differentiation factor 15 (GDF15) is associated with inflammation, oxidative stress, insulin…”
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ANGT_HUMAN[448–462], an Anorexigenic Peptide Identified Using Plasma Peptidomics by Sasaki, Sayaka, Oba, Kazuhito, Kodera, Yoshio, Itakura, Makoto, Shichiri, Masayoshi

“…Abstract The discovery of bioactive peptides is an important research target that enables the elucidation of the pathophysiology of human diseases and provides…”
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