Search Results - "Oates, Adam J."

Predicting benefit from anti-angiogenic agents in malignancy by Jubb, Adrian M, Oates, Adam J, Holden, Scott, Koeppen, Hartmut

“…A high probability of benefit is desirable to justify the choice of anti-angiogenic therapy from an ever-expanding list of expensive new anticancer agents…”
Get full text

Parenchymal brain injuries in abusive head trauma by Oates, Adam J., Sidpra, Jai, Mankad, Kshitij

“…The consequences of abusive head trauma (AHT) can be devastating for both the individual child and for wider society. Death is undoubtedly a very real…”
Get full text

The utility of Multicentre Epilepsy Lesion Detection (MELD) algorithm in identifying epileptic activity and predicting seizure freedom in MRI lesion-negative paediatric patients by Goel, Aimee, Seri, Stefano, Agrawal, Shakti, Kumar, Ratna, Sudarsanam, Annapurna, Carr, Bryony, Lawley, Andrew, Macpherson, Lesley, Oates, Adam J., Williams, Helen, Walsh, A. Richard, Lo, William B., Pepper, Joshua

“…Paediatric patients with drug-resistant focal epilepsy (DRFE) who have no clear focal lesion identified on conventional structural magnetic resonance imaging…”
Get full text

Traumatic disruption of dura at suture lines: a consistent finding in non-accidental head injury? by Gallo, Pasquale, Baig, Rehman Ali, Lo, William B., Oates, Adam J., Solanki, Guirish A.

Get full text

Sibling screening in suspected abusive head trauma: a proposed guideline by Mankad, Kshitij, Sidpra, Jai, Oates, Adam J., Calder, Alistair, Offiah, Amaka C., Choudhary, Arabinda

“…Abusive head trauma (AHT) is the leading cause of death from child abuse in children younger than 5 years. It is well documented that the infant contacts of…”
Get full text

International Consensus Statement on the Radiological Screening of Contact Children in the Context of Suspected Child Physical Abuse by Mankad, Kshitij, Sidpra, Jai, Mirsky, David M, Oates, Adam J, Colleran, Gabrielle C, Lucato, Leandro T, Kan, Elaine, Kilborn, Tracy, Agrawal, Nina, Teeuw, Arianne H, Kelly, Patrick, Zeitlin, Deborah, Carter, Jamieson, Debelle, Geoff D, Berger, Rachel P, Christian, Cindy W, Lindberg, Daniel M, Raissaki, Maria, Argyropoulou, Maria, Adamsbaum, Catherine, Cain, Timothy, van Rijn, Rick R, Silvera, V Michelle, Rossi, Andrea, Kemp, Alison M, Choudhary, Arabinda K, Offiah, Amaka C

“…Physical abuse is a common but preventable cause of long-term childhood morbidity and mortality. Despite the strong association between abuse in an index child…”
Get more information

Rate and severity of radiological features of physical abuse in children during the first UK-wide COVID-19 enforced national lockdown by Stivaros, Stavros, Paddock, Michael, Rajai, Azita, Cliffe, Helen, Connolly, Daniel JA, Dineen, Robert A, Dixon, Rachel, Edwards, Harriet, Evans, Emily, Halliday, Katherine, Jackson, Kandise, Landes, Caren, Oates, Adam J, Stoodley, Neil, Offiah, Amaka C

“…Rate and severity of radiological features of physical abuse in children during the first UK-wide COVID-19 enforced national lockdown.ObjectiveTo assess the…”
Get full text

Abusive head trauma: neuroimaging mimics and diagnostic complexities by Sidpra, Jai, Chhabda, Sahil, Oates, Adam J., Bhatia, Aashim, Blaser, Susan I., Mankad, Kshitij

“…Traumatic brain injury is responsible for approximately half of all childhood deaths from infancy to puberty, the majority of which are attributable to abusive…”
Get full text

A homozygous variant disrupting the PIGH start‐codon is associated with developmental delay, epilepsy, and microcephaly by Pagnamenta, Alistair T., Murakami, Yoshiko, Anzilotti, Consuelo, Titheradge, Hannah, Oates, Adam J., Morton, Jenny, Kinoshita, Taroh, Kini, Usha, Taylor, Jenny C.

“…Defective glycosylphosphatidylinositol (GPI)‐anchor biogenesis can cause a spectrum of predominantly neurological problems. For eight genes critical to this…”
Get full text

The radiological diagnosis of midgut volvulus — wow, it’s difficult by Oates, Adam J., Suleman, Nageena J., Low, Samantha B. L., Patel, Hiten J., Thyagarajan, Manigandan

Get full text

An overview of the analysis of DNA methylation in mammalian genomes by Shiraishi, Masahiko, Oates, Adam J, Sekiya, Takao

“…DNA methylation at position C5 of the pyrimidine ring of cytosine in mammalian genomes has received a great deal of research interest due to its importance in…”
Get more information

Methyl-CpG binding domain column chromatography as a tool for the analysis of genomic DNA methylation by Shiraishi, Masahiko, Sekiguchi, Azumi, Oates, Adam J, Terry, Michael J, Miyamoto, Yuji, Sekiya, Takao

Get full text

A comprehensive catalog of CpG islands methylated in human lung adenocarcinomas for the identification of tumor suppressor genes by SHIRAISHI, Masahiko, SEKIGUCHI, Azumi, TERRY, Michael J, OATES, Adam J, MIYAMOTO, Yuji, CHUU, Ying H, MUNAKATA, Miyo, SEKIYA, Takao

“…CpG island methylation is an important mechanism in gene silencing and is a key epigenetic event in cancer development. As yet, the number and identities of…”
Get full text

Delayed presentation of a caecal haematoma initially managed as appendicitis by Oates, Adam J., Sutcliffe, Jonathan, Stahlschmidt, Jens, Kraft, Jeannette K.

“…A 15-year-old boy with caecal haematoma required a right hemicolectomy due to development of small bowel obstruction and near caecal perforation having…”
Get full text

DNA methylation, a biomarker for colorectal cancer: implications for screening and pathological utility by Jubb, Adrian M, Quirke, Phil, Oates, Adam J

“…Currently up to one-third of colorectal cancer patients present with locally advanced or metastatic disease that precludes a surgical cure. Performance…”
Get full text

Standard of reporting for studies on inflammatory Bowel disease by Oates, Adam J, Tolan, Damian J M

Get more information

HOX gene clusters are hotspots of de novo methylation in CpG islands of human lung adenocarcinomas by SHIRAISHI, Masahiko, SEKIGUCHI, Azumi, OATES, Adam J, TERRY, Michael J, MIYAMOTO, Yuji

“…CpG island methylation results in the silencing of the associated gene and is an important step in tumorigenesis. Following a comprehensive isolation of CpG…”
Get full text

DNA Methylation, a Biomarker for Colorectal Cancer by JUBB, ADRIAN M., QUIRKE, PHIL, OATES, ADAM J.

“…: Currently up to one‐third of colorectal cancer patients present with locally advanced or metastatic disease that precludes a surgical cure. Performance…”
Get full text

The mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R), a putative breast tumor suppressor gene by Oates, A J, Schumaker, L M, Jenkins, S B, Pearce, A A, DaCosta, S A, Arun, B, Ellis, M J

“…Loss of heterozygosity (LOH) at the mannose 6-phosphate/insulin-like growth factor 2 receptor gene locus (M6P/IGF2R) on 6q26-27 has recently been demonstrated…”
Get full text

Segregation of partly melted molecules: isolation of CpG islands by polyacrylamide gel electrophoresis by Shiraishi, Masahiko, Oates, Adam J, Li, Xu, Chuu, Ying H, Sekiya, Takao

“…The technique of segregation of partly melted molecules (SPM) is a convenient and efficient method to isolate DNA fragments associated with CpG islands. The…”
Get more information