Search Results - "Oasa, Sho"

Thioflavin-T: application as a neuronal body and nucleolar stain and the blue light photo enhancement effect by Min, Jin-Hong, Sarlus, Heela, Oasa, Sho, Harris, Robert A.

“…Thioflavin-T (THT) is a common and indispensable tool for the study of amyloid pathologies and protein aggregation, both in vitro and for histological samples…”
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A Quantitative Study of Internal and External Interactions of Homodimeric Glucocorticoid Receptor Using Fluorescence Cross-Correlation Spectroscopy in a Live Cell by Tiwari, Manisha, Oasa, Sho, Yamamoto, Johtaro, Mikuni, Shintaro, Kinjo, Masataka

“…Glucocorticoid receptor (GRα) is a well-known ligand-dependent transcription-regulatory protein. The classic view is that unliganded GRα resides in the…”
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Increased intracellular crowding during hyperosmotic stress by Kitamura, Akira, Oasa, Sho, Kawaguchi, Haruka, Osaka, Misato, Vukojević, Vladana, Kinjo, Masataka

“…Hyperosmotic stress activates in live cells numerous processes and also promotes intracellular protein/RNA aggregation and phase separation. However, the time…”
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Small molecular decoys in Alzheimer's disease by Oasa, Sho, Kouznetsova, Valentina L, Tsigelny, Igor F, Terenius, Lars

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Homodimerization of glucocorticoid receptor from single cells investigated using fluorescence correlation spectroscopy and microwells by Oasa, Sho, Sasaki, Akira, Yamamoto, Johtaro, Mikuni, Shintaro, Kinjo, Masataka

“…•FCS can determine a 0.17nM concentration of EGFP with background correction.•The dissociation constant for homodimerization of GR was determined in the…”
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Relationship Between Homodimeric Glucocorticoid Receptor and Transcriptional Regulation Assessed via an In Vitro Fluorescence Correlation Spectroscopy-Microwell System by Oasa, Sho, Mikuni, Shintaro, Yamamoto, Johtaro, Kurosaki, Tsumugi, Yamashita, Daisuke, Kinjo, Masataka

“…Glucocorticoid receptor (GR) is a hormone-activated transcription regulatory protein involved in metabolism as well as adrenocortical responses to psychosocial…”
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Temperature and pH sensitivity of a stabilized self-nanoemulsion formed using an ionizable lipid-like material via an oil-to-surfactant transition by Tanaka, Hiroki, Oasa, Sho, Kinjo, Masataka, Tange, Kota, Nakai, Yuta, Harashima, Hideyoshi, Akita, Hidetaka

“…Nano-sized self-emulsion was prepared using ionizable lipid (SS-cleavable pH-Activated Lipid-like material), which had fusogenecity to anionic liposome with…”
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The interwoven fibril-like structure of amyloid-beta plaques in mouse brain tissue visualized using super-resolution STED microscopy by Johansson, Björn, Oasa, Sho, Muntsant Soria, Aida, Tiiman, Ann, Söderberg, Linda, Amandius, Ebba, Möller, Christer, Lannfelt, Lars, Terenius, Lars, Giménez-Llort, Lydia, Vukojević, Vladana

“…Standard neuropathologic analysis of Alzheimer's brain relies on traditional fluorescence microscopy, which suffers from limited spatial resolution due to…”
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Scanning‐Free functional Fluorescence Microscopy Imaging Toward Spatial Mapping of Biomolecular Information in Live Cell by Oasa, Sho, Krmpot, Aleksandar, Nikolic, Stanko, Clayton, Andrew, Tsigelny, Igor, Changeux, Jean‐Pierre, Terenius, Lars, Rigler, Rudolf, Vukojevic, Vladana

“…Live cells form signaling network and control it via molecular interactions and transporting processes. Through molecular interactions and transporting…”
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Cytosolic GPR37, but not GPR37L1, multimerization and its reversal by Parkin: A live cell imaging study by Li, Tianyi, Oasa, Sho, Ciruela, Francisco, Terenius, Lars, Vukojević, Vladana, Svenningsson, Per

“…Biochemical data have shown aggregated G protein‐coupled receptor 37 (GPR37) in the cytoplasm and Lewy bodies in Parkinson's disease (PD). Properly folded…”
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Mapping the Direction of Nucleocytoplasmic Transport of Glucocorticoid Receptor (GR) in Live Cells Using Two-Foci Cross-Correlation in Massively Parallel Fluorescence Correlation Spectroscopy (mpFCS) by Nikolić, Stanko N., Oasa, Sho, Krmpot, Aleksandar J., Terenius, Lars, Belić, Milivoj R., Rigler, Rudolf, Vukojević, Vladana

“…Nucleocytoplasmic transport of transcription factors is vital for normal cellular function, and its breakdown is a major contributing factor in many diseases…”
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Mapping the Spatiotemporal Heterogeneity of Biomolecules Concentration, Mobility and Local Environment in Live Cells using Quantitative Time-Resolved Confocal Fluorescence Microscopy Imaging Without Scanning and Fluorescence Lifetime Imaging Microscopy by Oasa, Sho, Krmpot, Aleksandar, Nikolic, Stanko, Terenius, Lars, Rigler, Rudolf, Vukojevic, Vladana

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Small Molecule Decoys of Aggregation for Elimination of A?-Peptide Toxicity by Oasa, S, Kouznetsova, VL, Tiiman, A, Vukojevic, V, Tsigelny, IF, Terenius, L

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Small Molecule Decoys of Aggregation for Elimination of Aβ-Peptide Toxicity by Oasa, Sho, Kouznetsova, Valentina L., Tiiman, Ann, Vukojević, Vladana, Tsigelny, Igor F., Terenius, Lars

“…Several lines of evidence suggest that a characteristic of the neuropathology of Alzheimer’s disease (AD) is the aggregation of the amyloid beta peptides (Aβ),…”
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A strategy for designing allosteric modulators of transcription factor dimerization by Oasa, Sho, Vukojević, Vladana, Rigler, Rudolf, Tsigelny, Igor F., Changeux, Jean-Pierre, Terenius, Lars

“…Transcription factors (TFs) are fundamental in the regulation of gene expression in the development and differentiation of cells. They may act as oncogenes and…”
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Functional Fluorescence Microscopy Imaging: Quantitative Scanning-Free Confocal Fluorescence Microscopy for the Characterization of Fast Dynamic Processes in Live Cells by Krmpot, Aleksandar J, Nikolić, Stanko N, Oasa, Sho, Papadopoulos, Dimitrios K, Vitali, Marco, Oura, Makoto, Mikuni, Shintaro, Thyberg, Per, Tisa, Simone, Kinjo, Masataka, Nilsson, Lennart, Terenius, Lars, Rigler, Rudolf, Vukojević, Vladana

“…Functional fluorescence microscopy imaging (fFMI), a time-resolved (21 μs/frame) confocal fluorescence microscopy imaging technique without scanning, is…”
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Dynamic Cellular Cartography: Mapping the Local Determinants of Oligodendrocyte Transcription Factor 2 (OLIG2) Function in Live Cells Using Massively Parallel Fluorescence Correlation Spectroscopy Integrated with Fluorescence Lifetime Imaging Microscopy (mpFCS/FLIM) by Oasa, Sho, Krmpot, Aleksandar J, Nikolić, Stanko N, Clayton, Andrew H. A, Tsigelny, Igor F, Changeux, Jean-Pierre, Terenius, Lars, Rigler, Rudolf, Vukojević, Vladana

“…Compartmentalization and integration of molecular processes through diffusion are basic mechanisms through which cells perform biological functions. To…”
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Interactions of ultrashort laser pulses with hemoglobin: Photophysical aspects and potential applications by Radmilović, Mihajlo D., Drvenica, Ivana T., Rabasović, Mihailo D., Ilić, Vesna Lj, Pavlović, Danica, Oasa, Sho, Vukojević, Vladana, Perić, Mina, Nikolić, Stanko N., Krmpot, Aleksandar J.

“…Hemoglobin (Hb), a life-sustaining and highly abundant erythrocyte protein, is not readily fluorescent. A few studies have already reported Two-Photon Excited…”
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