Search Results - "Oancea, Alina R."
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Involvement of a proapoptotic gene (BBC3) in islet injury mediated by cold preservation and rewarming
Published in American journal of physiology: endocrinology and metabolism (01-06-2016)“…Long-term pancreatic cold ischemia contributes to decreased islet number and viability after isolation and culture, leading to poor islet transplantation…”
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Human Pancreatic Islets Isolated From Donors With Elevated HbA1c Levels: Islet Yield and Graft Efficacy
Published in Cell transplantation (01-09-2015)“…The aim of this study was to investigate the effects of elevated donor HbA1c levels (type 2 diabetes, T2D) on the islet yield and functionality postisolation…”
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Maintaining functional islets through encapsulation in an injectable saccharide–peptide hydrogel
Published in Biomaterials (01-05-2013)“…Abstract Islet transplantation offers a promising treatment for type 1 diabetes (T1D). However, a major hurdle in this treatment is the rapid loss of…”
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Inflammatory biomarkers in the blood and pancreatic tissue of organ donors that predict human islet isolation success and function
Published in Islets (02-01-2020)“…The pancreas of brain-dead donors is the primary source of islets for transplantation. However, brain death mediates systemic inflammation, which may affect…”
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