Search Results - "Oakley, Jacqueline"

loss-of-function screen reveals SNX5 and SNX6 as potential components of the mammalian retromer by Wassmer, Thomas, Attar, Naomi, Bujny, Miriam V, Oakley, Jacqueline, Traer, Colin J, Cullen, Peter J

“…The mammalian retromer is a multimeric protein complex involved in mediating endosome-to-trans-Golgi-network retrograde transport of the cation-independent…”
Get full text

Balancing constraints and requirements in an application process by McLachlan, Stela, Evans, Katharine, Whitehorn, Rebecca, Turner, Emma, Oakley, Jacqueline, Boyd, Andy, Flaig, Robin

“…ObjectivesDeveloping a rigorous application process for linked data within the UK Longitudinal Linkage Collaboration’s Trusted Research Environment (TRE)…”
Get full text

The challenges of developing an application process for a new linked data resource by McLachlan, Stela, Berman, Samantha, Evans, Katharine, Levein, Christie, Whitehorn, Rebecca, Oakley, Jacqueline, Campbell, Kirsteen, Flaig, Robin

“…ObjectivesDeveloping a rigorous application process for COVID-19 linked data within the UK Longitudinal Linkage Collaboration’s Trusted Research Environment…”
Get full text

How public and participant voices have influenced the UK Longitudinal Linkage Collaboration and its Trusted Research Environment by Campbell, Kirsteen, Whitehorn, Rebecca, Boyd, Andy, Flaig, Robin, McLachlan, Stela, Levein, Christie, Oakley, Jacqueline, Chave, Sarah, Gregg, Michael, Ogunleye, Della

“…ObjectivesUK longitudinal population studies have complex governance structures and participant safeguards. As a new Trusted Research Environment (TRE) for >20…”
Get full text

A public panel reviews applications and questions applicants: Team member and public contributor discuss a transparent and inclusive approach to data access reviews by Campbell, Kirsteen, Whitehorn, Rebecca, Browning, Simon, Harmston, Rebecca, Harris, Ray, Huang, Szu-Chia, Moylan, Dianna, Williams, Karen, Oakley, Jacqueline, Evans, Katharine, McLachlan, Stela, Thomas, Richard, Turner, Emma, Flaig, Robin, Boyd, Andy

“…ObjectivesWe created a panel with members of the public and longitudinal study participants who review our data access requests. This panel forms an integral…”
Get full text

Tyrphostin A23 Inhibits Internalization of the Transferrin Receptor by Perturbing the Interaction between Tyrosine Motifs and the Medium Chain Subunit of the AP-2 Adaptor Complex by Banbury, David N, Oakley, Jacqueline D, Sessions, Richard B, Banting, George

“…Several intracellular membrane trafficking events are mediated by tyrosine-containing motifs within the cytosolic domains of integral membrane proteins. Many…”
Get full text

Triggering of Apoptosis is not Sufficient to Induce Human Immunodeficiency Virus Gene Expression by Oakley, Jacqueline, Taher, Mohiuddin, Hershey, Chad, Aggarwal, Puneet, Estwani, Isam, Valerie, Kristoffer

“…We examined whether there is any causative link between apoptosis and HIV gene expression elicited in response to ultraviolet light (UV) and ionizing radiation…”
Get full text

Activation of NF-κB and p38 MAP Kinase Is Not Sufficient for Triggering Efficient HIV Gene Expression in Response to Stress by Taher, Mohiuddin M, Oakley, Jacqueline D, Hershey, Chad, Valerie, Kristoffer

“…Recent studies have established an essential role for p38 MAP kinase in UV activation of human immunodeficiency virus (HIV) gene expression. However, p38 MAP…”
Get full text

The Retromer Coat Complex Coordinates Endosomal Sorting and Dynein-Mediated Transport, with Carrier Recognition by the trans-Golgi Network by Wassmer, Thomas, Attar, Naomi, Harterink, Martin, van Weering, Jan R.T., Traer, Colin J., Oakley, Jacqueline, Goud, Bruno, Stephens, David J., Verkade, Paul, Korswagen, Hendrik C., Cullen, Peter J.

“…Early endosome-to-trans-Golgi network (TGN) transport is organized by the retromer complex. Consisting of cargo-selective and membrane-bound subcomplexes,…”
Get full text

SNX4 coordinates endosomal sorting of TfnR with dynein-mediated transport into the endocytic recycling compartment by Carlton, Jez G, Stephens, David J, Palmer, Krysten J, Rutherford, Anna C, Oakley, Jacqueline, Kremerskothen, Joachim, Wassmer, Thomas, Attar, Naomi, Cullen, Peter J, Traer, Colin J

“…SNX-BAR proteins are a sub-family of sorting nexins implicated in endosomal sorting. Here, we establish that through its phox homology (PX) and…”
Get full text

Role of the p38 and MEK-1/2/p42/44 MAP kinase pathways in the differential activation of human immunodeficiency virus gene expression by ultraviolet and ionizing radiation by Taher, M M, Hershey, C M, Oakley, J D, Valerie, K

“…Ultraviolet (UV) radiation is a potent activator of human immunodeficiency virus (HIV) gene expression in a HeLa cell clone having stably integrated copies of…”
Get full text

Role of the p38 and MEK-½/p42/44 MAP Kinase Pathways in the Differential Activation of Human Immunodeficiency Virus Gene Expression by Ultraviolet and Ionizing Radiation by Taher, Mohiuddin M., Hershey, Chad M., Oakley, Jacqueline D., Valerie, Kristoffer

“…ABSTRACT Ultraviolet (UV) radiation is a potent activator of human immunodeficiency virus (HIV) gene expression in a HeLa cell clone having stably integrated…”
Get full text

Role of the p38 and MEK-1/2p42/44 MAP kinase pathways in the differention activation of human immunodeficiency virus gene expression by ultraviolet and ionizing radiation by Taher, Mohiuddin M, Hershey, Chad M, Oakley, Jacqueline D, Kristoffer Valerie

“…Ultraviolet (UV) radiation is a potent activator of human immunodeficiency virus (HIV) gene expression in a HeLa cell clone having stably integrated copies of…”
Get full text

Role of the p38 and MEK-½/p42/44 MAP Kinase Pathways in the Differential Activation of Human Immunodeficiency Virus Gene Expression by Ultraviolet and Ionizing Radiation by Taher, Mohiuddin M., Hershey, Chad M., Oakley, Jacqueline D., Valerie, Kristoffer

“…Ultraviolet (UV) radiation is a potent activator of human immunodeficiency virus (HIV) gene expression in a HeLa cell clone having stably integrated copies of…”
Get full text