Search Results - "Oakey, R E"

Lower serum oestrogen concentrations associated with faster intestinal transit by LEWIS, S. J, HEATON, K. W, OAKEY, R. E, MCGARRIGLE, H. H. G

“…Increased fibre intake has been shown to reduce serum oestrogen concentrations. We hypothesized that fibre exerts this effect by decreasing the time available…”
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The effects of fasting on plasma corticosterone kinetics in rats by Woodward, C. J. H., Hervey, G. R., Oakey, R. E., Whitaker, E. M.

“…Plasma corticosterone clearance in anaesthetized rats was measured from the disappearance of radioactivity after a bolus injection of [3H]corticosterone. Mean…”
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Cloning of a cDNA for Steroid Sulfatase: Frequent Occurrence of Gene Deletions in Patients with Recessive X Chromosome-Linked Ichthyosis by Bonifas, Jeannette M., Morley, Bernard J., Oakey, Robert E., Kan, Yuet Wai, Epstein, Ervin H.

“…A human steroid sulfatase (steryl-sulfatase; steryl-sulfate sulfohydrolase, EC 3.1.6.2) cDNA 2.4 kilobases long was isolated from a human placental λ gt11 cDNA…”
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Why so much oestriol? A comparison of the aromatisation of androstenedione and 16 alpha-hydroxyandrostenedione when incubated alone or together with human placental microsomes by Othman, Y S, Oakey, R E

“…Estimates of the relative abundance of 16 alpha-hydroxy- and 16-deoxyoestrogens in late pregnancy urine lie between 13:1 and 5:1, yet the ratio of the…”
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Steroids in human intrauterine fluids of early pregnancy by Atkinson, G, Campbell, D J, Cawood, M L, Oakey, R E

“…Little is known of the hormone environment of the developing early human embryo. We have therefore measured selected steroids in the intrauterine fluids of…”
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Steroid sulphatase deficiency: identification of heterozygotes using hydrolysis of dehydroepiandrosterone sulphate by peripheral leucocytes by Lowis, E I, Oakey, R E

“…Diagnosis of X-linked recessive ichthyosis, which is expressed only in males, can readily be made by measurement of leucocyte steroid sulphatase activity…”
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Serum cortisol binding capacity measured with concanavalin A-sepharose in patients with a recent inflammatory response by Bladon, P.T., Rowlands, T.E., Whittaker, June A., Oakey, R.E.

“…It has been suggested that elastase released from activated neutrophils degrades cortisol binding globulin. A novel assay for serum cortisol binding capacity…”
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Urinary multiple marker screening for Down's syndrome by Cuckle, H S, Iles, R K, Sehmi, I K, Chard, T, Oakey, R E, Davies, S, Ind, T

“…We have examined the possibility of using multiple markers in maternal urine rather than serum in order to screen for Down's syndrome. Urine samples were…”
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Intestinal absorption of oestrogen: the effect of altering transit-time by Lewis, S J, Oakey, R E, Heaton, K W

“…The mechanism by which a high fibre diet may reduce serum oestrogens is unknown. We hypothesized that time is a rate-limiting factor in oestrogen absorption…”
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Steroid sulphatase deficiency by Oakey, R E

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Hydrolysis of deoxycorticosterone-21-yl sulphate and dehydroepiandrosterone sulphate by microsomal preparations of human placentae: evidence for a common enzyme by Egyed, J, Oakey, R E

“…The human placenta can hydrolyse both dehydroepiandrosterone-3 beta-yl sulphate (DHASO4-) and deoxycorticosterone-21-yl sulphate (DOCSO4-). There is some…”
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A method for the determination of sex hormone binding globulin using Concanavalin A-sepharose by Whittaker, J A, Cawood, M L, Oakey, R E

“…A binding assay for sex hormone binding globulin (SHBG) has been developed in which SHBG is saturated with tritiated dihydrotestosterone (DHT). Separation of…”
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Oestriol and non-protein-bound oestriol concentrations in human peripheral plasma before labour and delivery by Moutsatsou, V, Oakey, R E

“…The concentration of oestriol and the proportion of this hormone not bound to plasma protein were measured using radioimmunoassay and centrifugal…”
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Evidence for secondary 5 alpha-reductase deficiency in genital and supra-pubic skin of subjects with androgen insensitivity syndrome by Wilson, S C, Oakey, R E, Scott, J S

“…The activity of 5 alpha-reductase in genital and supra-pubic skin (homogenate or fibroblasts) from subjects with complete or incomplete androgen insensitivity…”
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Non-protein-bound oestradiol and progesterone in human peripheral plasma before labour and delivery by Anderson, P J, Hancock, K W, Oakey, R E

“…Plasma samples were obtained at weekly intervals from the peripheral circulation of 12 women in the last 2-7 weeks of pregnancy. The concentrations of…”
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Stimulation by polypeptides of dehydroepiandrosterone sulphate synthesis in human fetal adrenal slices by Brown, T J, Ginz, B, Milne, C M, Oakey, R E

“…Slices of human fetal adrenal glands (obtained after abortion at 10-18 weeks of gestation) were superfused sequentially with buffer or with buffer…”
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Antenatal detection of placental steroid sulphatase deficiency by measurement of urinary 16 alpha-hydroxydehydroepiandrosterone sulphate by Wilmot, R L, Mawson, R J, Oakey, R E

“…A simple gas chromatographic technique for the measurement of 16 alpha-hydroxydehydroepiandrosterone sulphate in urine from pregnant women is described. An…”
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Pathological mechanisms in polycystic ovary syndrome: modulation of LH pulsatility by progesterone by Molloy, B G, El Sheikh, M A, Chapman, C, Oakey, R E, Hancock, K W, Glass, M R

“…The pulsatile discharge of luteinizing hormone (LH) in nine patients with polycystic ovary syndrome (PCO) and nine patients with amenorrhoea but without PCO,…”
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Steroid metabolism in testes of patients with incomplete masculinization due to androgen insensitivity or 17 beta-hydroxysteroid dehydrogenase deficiency and normally differentiated males by Wilson, S C, Oakey, R E, Scott, J S

“…For purposes of establishing suitable controls in studies of patients with a suspected enzyme deficiency, activities of enzymes involved in the biosynthesis of…”
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Estrogen excretion in pregnant women with leprosy: evidence of diminished fetoplacental function by Duncan, M E, Oakey, R E

“…Estrogen excretion was assayed in 64 women with leprosy and 15 healthy control women. The mean estrogen excretion was lower in women with leprosy than in…”
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