Search Results - "Oakes, S."

Mapping the Mechanical and Immunological Profiles of Polymeric Microneedles to Enable Vaccine and Immunotherapy Applications by Shah, Shrey A, Oakes, Robert S, Kapnick, Senta M, Jewell, Christopher M

“…Biomaterials hold great promise for vaccines and immunotherapy. One emerging biomaterials technology is microneedle (MNs) delivery. MNs are arrays of…”
Get full text

Retrievable hydrogels for ovarian follicle transplantation and oocyte collection by Rios, Peter D., Kniazeva, Ekaterina, Lee, Hoi Chang, Xiao, Shuo, Oakes, Robert S., Saito, Eiji, Jeruss, Jacqueline S., Shikanov, Ariella, Woodruff, Teresa K., Shea, Lonnie D.

“…Cancer survivorship rates have drastically increased due to improved efficacy of oncologic treatments. Consequently, clinical concerns have shifted from solely…”
Get full text

New Magnetic Resonance Imaging-Based Method for Defining the Extent of Left Atrial Wall Injury After the Ablation of Atrial Fibrillation by McGann, Christopher J., MD, Kholmovski, Eugene G., PhD, Oakes, Robert S., BS, Blauer, Joshua J.E., BS, Daccarett, Marcos, MD, Segerson, Nathan, MD, Airey, Kelly J., MD, Akoum, Nazem, MD, Fish, Eric, Badger, Troy J., MD, DiBella, Edward V.R., PhD, Parker, Dennis, PhD, MacLeod, Rob S., PhD, Marrouche, Nassir F., MD

“…Objectives We describe a noninvasive method of detecting and quantifying left atrial (LA) wall injury after pulmonary vein antrum isolation (PVAI) in patients…”
Get full text

Engineering the lymph node environment promotes antigen-specific efficacy in type 1 diabetes and islet transplantation by Gammon, Joshua M., Carey, Sean T., Saxena, Vikas, Eppler, Haleigh B., Tsai, Shannon J., Paluskievicz, Christina, Xiong, Yanbao, Li, Lushen, Ackun-Farmmer, Marian, Tostanoski, Lisa H., Gosselin, Emily A., Yanes, Alexis A., Zeng, Xiangbin, Oakes, Robert S., Bromberg, Jonathan S., Jewell, Christopher M.

“…Antigen-specific tolerance is a key goal of experimental immunotherapies for autoimmune disease and allograft rejection. This outcome could selectively inhibit…”
Get full text

Engineered immunological niches to monitor disease activity and treatment efficacy in relapsing multiple sclerosis by Morris, Aaron H., Hughes, Kevin R., Oakes, Robert S., Cai, Michelle M., Miller, Stephen D., Irani, David N., Shea, Lonnie D.

“…Relapses in multiple sclerosis can result in irreversible nervous system tissue injury. If these events could be detected early, targeted immunotherapy could…”
Get full text

Introduction to the NOAA Integrated Ecosystem Assessment Program: Advancing Ecosystem Based Management by Monaco, Mark E., Spooner, E., Oakes, S. A., Harvey, C. J., Kelble, C. R.

“…In the marine science community of practice, the concept of ecosystem-based management (EBM) is a management strategy that incorporates the entire ecosystem,…”
Get full text

Engineering Biomaterials to Direct Innate Immunity by Oakes, Robert S., Froimchuk, Eugene, Jewell, Christopher M.

“…Small alterations during early stages of innate immune response can drive large changes in how adaptive immune cells develop and function during protective…”
Get full text

Suppression of epithelial–mesenchymal transition and apoptotic pathways by miR-294/302 family synergistically blocks let-7-induced silencing of self-renewal in embryonic stem cells by Guo, W-T, Wang, X-W, Yan, Y-L, Li, Y-P, Yin, X, Zhang, Q, Melton, C, Shenoy, A, Reyes, N A, Oakes, S A, Blelloch, R, Wang, Y

“…The embryonic stem cell (ESC)-enriched miR-294/302 family and the somatic cell-enriched let-7 family stabilizes the self-renewing and differentiated cell…”
Get full text

Dissecting regulatory T cell expansion using polymer microparticles presenting defined ratios of self-antigen and regulatory cues by Bridgeman, Christopher J, Shah, Shrey A, Oakes, Robert S, Jewell, Christopher M

“…Biomaterials allow for the precision control over the combination and release of cargo needed to engineer cell outcomes. These capabilities are particularly…”
Get full text

Self‐Assembly of Immune Signals to Program Innate Immunity through Rational Adjuvant Design by Bookstaver, Michelle L., Zeng, Qin, Oakes, Robert S., Kapnick, Senta M., Saxena, Vikas, Edwards, Camilla, Venkataraman, Nishedhya, Black, Sheneil K., Zeng, Xiangbin, Froimchuk, Eugene, Gebhardt, Thomas, Bromberg, Jonathan S., Jewell, Christopher M.

“…Recent clinical studies show activating multiple innate immune pathways drives robust responses in infection and cancer. Biomaterials offer useful features to…”
Get full text

Loss of mammary epithelial prolactin receptor delays tumor formation by reducing cell proliferation in low-grade preinvasive lesions by OAKES, S. R, ROBERTSON, F. G, KENCH, J. G, GARDINER-GARDEN, M, WAND, M. P, GREEN, J. E, ORMANDY, C. J

“…Top quartile serum prolactin levels confer a twofold increase in the relative risk of developing breast cancer. Prolactin exerts this effect at an ill defined…”
Get full text

Microneedle array delivery of Yersinia pestis recapitulates bubonic plague by Price, Sarah L., Oakes, Robert S., Gonzalez, Rodrigo J., Edwards, Camilla, Brady, Amanda, DeMarco, Jennifer K., von Andrian, Ulrich H., Jewell, Christopher M., Lawrenz, Matthew B.

“…Fleas transmit Yersinia pestis directly within the dermis of mammals to cause bubonic plague. Syringe-mediated inoculation is widely used to recapitulate…”
Get full text

Predictors of Fatality in Postdiarrheal Hemolytic Uremic Syndrome by Oakes, Robert S, Siegler, Richard L, McReynolds, Markham A, Pysher, Theodore, Pavia, Andrew T

“…Describe the cause of deaths among patients with postdiarrheal hemolytic uremic syndrome (HUS) and identify predictors of death at the time of hospital…”
Get full text

A fully integrated undergraduate introductory biology and chemistry course with a community‐based focus I: Vision, design, implementation, and development by Beers, Melissa A., Hall, Mona L., Matthews, Adam G. W., Elmore, Donald E., Oakes, Elizabeth S. C., Goss, John W., Radhakrishnan, Mala L.

“…We describe a first‐semester, integrated, introductory biology and chemistry course for undergraduates at Wellesley College in Wellesley, MA, USA. Our vision…”
Get full text

A fully integrated undergraduate introductory biology and chemistry course with a community‐based focus II: Assessment of course effectiveness by Pociask, Sarah, Weerapana, Akila, Taylor, Pamela, Radhakrishnan, Mala L., Oakes, Elizabeth S. C., Matthews, Adam G. W., Elmore, Donald E.

“…In the Fall of 2016, we created an integrated introductory biology/chemistry course for first‐semester students at Wellesley College. This course was designed…”
Get full text

Television viewing and low participation in vigorous recreation are independently associated with obesity and markers of cardiovascular disease risk: EPIC-Norfolk population-based study by JAKES, R. W, DAY, N. E, KHAW, K-T, LUBEN, R, OAKES, S, WELCH, A, BINGHAM, S, WAREHAM, N. J

“…This study describes the associations between sedentary behaviour (television viewing) and participation in vigorous recreational activity with obesity and…”
Get full text

Integrated microelectrode array and microfluidics for temperature clamp of sensory neurons in culture by Pearce, Thomas M, Wilson, J Adam, Oakes, S George, Chiu, Shing-Yan, Williams, Justin C

“…A device for cell culture is presented that combines MEMS technology and liquid-phase photolithography to create a microfluidic chip that influences and…”
Get more information

Duration of oliguria and anuria as predictors of chronic renal-related sequelae in post-diarrheal hemolytic uremic syndrome by Oakes, Robert S., Kirkhamm, Justin K., Nelson, Raoul D., Siegler, Richard L.

“…Prior long-term retrospective studies have described renal sequelae in 25–50% of postdiarrheal hemolytic uremic syndrome (HUS) survivors, but the ability to…”
Get full text

Temporal left atrial lesion formation after ablation of atrial fibrillation by Badger, Troy J., MD, Oakes, Robert S., BS, Daccarett, Marcos, MD, Burgon, Nathan S., BS, Akoum, Nazem, MD, Fish, Eric N, Blauer, Joshua J.E., BS, Rao, Swati N, Adjei-Poku, Yaw, BS, Kholmovski, Eugene G., PhD, Vijayakumar, Sathya, MS, Di Bella, Edward V.R., PhD, MacLeod, Rob S., PhD, Marrouche, Nassir F., MD, FHRS

“…Background Atrial fibrillation (AF) ablation uses radiofrequency (RF) energy to induce thermal damage to the left atrium (LA) in an attempt to isolate AF…”
Get full text

Residential area deprivation predicts smoking habit independently of individual educational level and occupational social class. A cross sectional study in the Norfolk cohort of the European Investigation into Cancer (EPIC-Norfolk) by Shohaimi, S, Luben, R, Wareham, N, Day, N, Bingham, S, Welch, A, Oakes, S, Khaw, K-T

“…Objectives: To investigate the independent association between individual and area based measures of socioeconomic status and cigarette smoking habit. Design…”
Get full text