Search Results - "Oakes, Joshua M."
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Nicotine and the renin-angiotensin system
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-11-2018)“…Cigarette smoking is the single most important risk factor for the development of cardiovascular and pulmonary diseases (CVPD). Although cigarette smoking has…”
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Effects of Chronic Nicotine Inhalation on Systemic and Pulmonary Blood Pressure and Right Ventricular Remodeling in Mice
Published in Hypertension (Dallas, Tex. 1979) (01-05-2020)“…Cigarette smoking is the single most important risk factor for the development of cardiovascular and pulmonary diseases; however, the role of nicotine in the…”
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3
Genetic Disruption of Guanylyl Cyclase/Natriuretic Peptide Receptor-A Triggers Differential Cardiac Fibrosis and Disorders in Male and Female Mutant Mice: Role of TGF-β1/SMAD Signaling Pathway
Published in International journal of molecular sciences (29-09-2022)“…The global targeted disruption of the natriuretic peptide receptor-A (NPRA) gene ( ) in mice provokes hypertension and cardiovascular dysfunction. The…”
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Nicotine and novel tobacco products drive adverse cardiac remodeling and dysfunction in preclinical studies
Published in Frontiers in cardiovascular medicine (06-10-2022)“…The heart undergoes structural and functional changes in response to injury and hemodynamic stress known as cardiac remodeling. Cardiac remodeling often…”
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AICAR prevents heat-induced sudden death in RyR1 mutant mice independent of AMPK activation
Published in Nature medicine (01-02-2012)“…Mutations in the type I ryanodine receptor (RYR1), a calcium channel, leads to stimulus-induced pathological muscle contractions, including malignant…”
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Abstract 046: Chronic Nicotine Inhalation Promotes the Development of Hypertension
Published in Hypertension (Dallas, Tex. 1979) (01-09-2019)“…Abstract only While smoking is a proven risk factor for stroke and heart attacks, whether it contributes to the development of hypertension is still unclear…”
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Chronic Nicotine Inhalation Promotes the Development of Pulmonary Hypertension
Published in The FASEB journal (01-04-2019)“…Pulmonary hypertension is a condition of increased blood pressure within the arteries of the lungs, leading to clinical symptoms including shortness of breath,…”
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Blockade of Cardiac Hypertrophy and Fibrosis by TGF‐Beta 1 Receptor Antagonist in Npr1 Gene‐Knockout Mice
Published in The FASEB journal (01-04-2019)“…Genetic disruption of guanylyl cyclase/natriuretic peptide receptor‐A (GC‐A/NPRA) gene (Npr1) in mice triggers cardiac hypertrophy, fibrosis, and remodeling…”
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Chronic Nicotine Inhalation Promotes Differential Remodeling of the Right and Left Ventricles in Mice
Published in The FASEB journal (01-04-2020)“…Abstract only Introduction Cigarette smoking continues to decline in the United States, but a rise in e‐cigarette use poses a threat to human health…”
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10
Effects of Chronic Nicotine Inhalation on Systemic and Pulmonary Blood Pressure and Right Ventricular Remodeling in Mice
Published in The FASEB journal (01-04-2020)“…Abstract only Cigarette smoking is the single most important risk factor for the development of cardiovascular and pulmonary diseases (CVPD), however, the role…”
Get full text
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