Search Results - "Oakes, Alissa"

Nonhuman IAPP Variants Inhibit Human IAPP Aggregation by Oakes, Alissa, Menefee, Kate, Lamba, Arleen, Palato, Larry M, Rinauro, Dillon J, Tun, Angela, Jauregui, Betssy, Chang, Kevin, Nogaj, Luiza A, Moffet, David A

“…To identify naturally occurring variants of IAPP capable of inhibiting the aggregation of human IAPP and protecting living cells from the toxic effects of…”
Get more information

Complement or Insult: the emerging link between complement cascade deficiencies and pathology of myeloid malignancies by Oakes, Alissa, Liu, Yuchen, Dubielecka, Patrycja M

“…The complement cascade is an ancient and highly conserved arm of the immune system. The accumulating evidence highlights elevated activity of the complement…”
Get full text

Complement Factor I (CFI) Deficiency Is Linked to Alterations in Humoral Immunity and Accelerated Development of JAK2V617F-Dependent Phenotype by Oakes, Alissa, Chorzalska, Anna D, Bonal, Dennis M, Reagan, John L, Dubielecka, Patrycja M

Get full text

Correlating Indigenous Peruvian Women's Distance to Cusco and Their Access to Healthcare, and Investigating the Effect of Cat's Claw Extracts on HeLa Cells by Lamba, Arleen, Oakes, Alissa, Roberts, Lia, Deprele, Sylvine, Nogaj, Luiza

“…Uncaria tomentosa, or Cat's Claw, is a large woody vine plant that is indigenous to the Amazonian rain forest. The roots and bark of cat's claw have been used…”
Get full text

Successful Engraftment of Murine JAK2V617F MPN-like Disease into Unconditioned Mice by Bonal, Dennis M, Chorzalska, Anna D, Oakes, Alissa, Brown, Valeria, Reagan, John L, Lee, Seo-Ho, Dubielecka, Patrycja M

Get full text

Evaluation of a summer program for minority high school students in the clinical cancer center: The Future Gen Cancer Scholars program by Ollila, Thomas, Mega, Anthony E., Martinez, Boris, Salisbry, Paula, Neville, Annabelle, Johnson, Janell, Dickens, Brett, Tarantino, John, Omoaregba, Luckson, Oakes, Alissa, Safran, Howard

“…e13703 Background: Individuals from minoritized communities receive less cancer screening, have higher stage at cancer diagnosis, and experience higher death…”
Get full text

Dysfunctional Stromal Pathways Mark Early Changes within the Bone Marrow Microenvironment in JAK2 V617F-Driven Model of Myeloproliferative Neoplasm by Bonal, Dennis M, Chorzalska, Anna Dorota, Oakes, Alissa, Pardo, Makayla, Creane, Zoe, Lee, Seo-Ho, Oyelola, Omonike, Reagan, John L., Olszewski, Adam, Niroula, Rabin, Donnelly, Stephen, Mills, Joslyn, Bertone, Paul, Dubielecka, Patrycja M

“…Background: JAK2V617F (JAK2VF) is the primary driver mutation in classical myeloproliferative neoplasms (MPN). JAK2VF is present decades prior to diagnosis…”
Get full text

Loss of Complement Factor I (Cfi) a Negative Regulator of Complement Cascade Activity Exacerbates JAK2V617F-Dependent Phenotype by Oakes, Alissa, Bonal, Dennis M, Creane, Zoe, Oh, Hyunju, Chorzalska, Anna Dorota, Sadler, Brooke, Reagan, John L., Niroula, Rabin, Olszewski, Adam J, Haller, Gabriel, Donnelly, Stephen, Dubielecka, Patrycja M

“…Background: The current evidence suggests that inflammatory phenotype contributes to the pathogenesis of myeloproliferative neoplasms (MPNs). While our…”
Get full text

Abstract 2559: Pharmacological characterization of sigma-2 receptor ligand-induced metabolic stimulation in human SK-N-SH neuroblastoma cells by McVeigh, Bridget M., Oakes, Alissa K., Liu, Cheri Z., Mesangeau, Christophe, Alsharif, Walid F., McCurdy, Christopher R., Bowen, Wayne D.

“…Abstract We have previously reported a novel metabolically stimulative function of the sigma-2 receptor, with stimulation of glycolytic hallmarks; effects…”
Get full text

Whole Genome Sequencing Identifies a Recurrent Mutation in Complement Factor I (CFI) in Primary Myelofibrosis (PMF) by Sadler, Brooke, Chorzalska, Anna D, Bonal, Dennis M, Haller, Gabe, Oakes, Alissa, Petersen, Max, Liu, Yuchen, Olszewski, Adam, Reagan, John L, Egan, Pamela C, Niroula, Rabin, Treaba, Diana O, Hobbs, Gabriela, Oh, Stephen T., Di Paola, Jorge, Baxter, Joanna E, Dubielecka, Patrycja M

“…Background: The known driver mutations in PMF (including JAK2, CALR, and MPL) do not explain the highly inflammatory phenotype associated with this disease…”
Get full text

Transcriptomics of acute myeloid leukaemia core bone marrow biopsies reveals distinct therapy response‐specific osteo‐mesenchymal profiles by Treaba, Diana O., Bonal, Dennis M., Chorzalska, Anna, Castillo‐Martin, Mireia, Oakes, Alissa, Pardo, Makayla, Petersen, Max, Schorl, Christoph, Hopkins, Kelsey, Melcher, Dean, Zhao, Ting C., Liang, Olin, So, Eui‐Young, Reagan, John, Olszewski, Adam J., Butera, James, Anthony, Douglas C., Rintels, Peter, Quesenberry, Peter, Dubielecka, Patrycja M.

“…Summary While the bone marrow (BM) microenvironment is significantly remodelled in acute myeloid leukaemia (AML), molecular insight into AML‐specific…”
Get full text

Amyloidogenicity of naturally occurring full‐length animal IAPP variants by Palato, Larry M., Pilcher, Shannon, Oakes, Alissa, Lamba, Arleen, Torres, Jaris, Ledesma Monjaraz, Litza I., Munoz, Crystabel, Njoo, Edward, Rinauro, Dillon J., Menefee, Kate Alexandra, Tun, Angela, Jauregui, Betssy L., Shapiro, Sarah, Nossiff, Olivia H., Olivares, Eileen, Chang, Kevin, Nguyen, Viviane, Nogaj, Luiza A., Moffet, David A.

“…The aggregation of the 37‐amino acid polypeptide human islet amyloid polypeptide (hIAPP), as either insoluble amyloid or as small oligomers, appears to play a…”
Get full text