Search Results - "OZTOP, Ilker"

The Host Proteins Transportin SR2/TNPO3 and Cyclophilin A Exert Opposing Effects on HIV-1 Uncoating by Shah, Vaibhav B, Shi, Jiong, Hout, David R, Oztop, Ilker, Krishnan, Lavanya, Ahn, Jinwoo, Shotwell, Matthew S, Engelman, Alan, Aiken, Christopher

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The Requirement for Cellular Transportin 3 (TNPO3 or TRN-SR2) during Infection Maps to Human Immunodeficiency Virus Type 1 Capsid and Not Integrase by KRISHNAN, Lavanya, MATREYEK, Kenneth A, OZTOP, Ilker, LEE, Kyeongeun, TIPPER, Christopher H, XIANG LI, DAR, Mohd J, KEWALRAMANI, Vineet N, ENGELMAN, Alan

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Human Immunodeficiency Virus Type 1 Capsid Mutation N74D Alters Cyclophilin A Dependence and Impairs Macrophage Infection by AMBROSE, Zandrea, LEE, Kyeongeun, KEWALRAMANI, Vineet N, NDJOMOU, Jean, HONGZHAN XU, OZTOP, Ilker, MATOUS, James, TAKEMURA, Taichiro, UNUTMAZ, Derya, ENGELMAN, Alan, HUGHES, Stephen H

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Structural basis for nuclear import of splicing factors by human Transportin 3 by Maertens, Goedele N., Cook, Nicola J., Wang, Weifeng, Hare, Stephen, Gupta, Saumya Shree, Öztop, Ilker, Lee, KyeongEun, Pye, Valerie E., Cosnefroy, Ophélie, Snijders, Ambrosius P., KewalRamani, Vineet N., Fassati, Ariberto, Engelman, Alan, Cherepanov, Peter

“…Transportin 3 (Tnpo3, Transportin-SR2) is implicated in nuclear import of splicing factors and HIV-1 replication. Herein, we show that the majority of cellular…”
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Mcl-1 determines the Bax dependency of Nbk/Bik-induced apoptosis by Gillissen, Bernhard, Essmann, Frank, Hemmati, Philipp G, Richter, Antje, Richter, Anja, Öztop, Ilker, Chinnadurai, Govindaswamy, Dörken, Bernd, Daniel, Peter T

“…B cell lymphoma 2 (Bcl-2) homology domain 3 (BH3)-only proteins of the Bcl-2 family are important functional adaptors that link cell death signals to the…”
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Flexible use of nuclear import pathways by HIV-1 by Lee, KyeongEun, Ambrose, Zandrea, Martin, Thomas D, Oztop, Ilker, Mulky, Alok, Julias, John G, Vandegraaff, Nick, Baumann, Joerg G, Wang, Rui, Yuen, Wendy, Takemura, Taichiro, Shelton, Kenneth, Taniuchi, Ichiro, Li, Yuan, Sodroski, Joseph, Littman, Dan R, Coffin, John M, Hughes, Stephen H, Unutmaz, Derya, Engelman, Alan, KewalRamani, Vineet N

“…HIV-1 replication requires transport of nascent viral DNA and associated virion proteins, the retroviral preintegration complex (PIC), into the nucleus. Too…”
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Flexible Use of Nuclear Import Pathways by HIV-1 by Lee, KyeongEun, Ambrose, Zandrea, Martin, Thomas D., Oztop, Ilker, Mulky, Alok, Julias, John G., Vandegraaff, Nick, Baumann, Joerg G., Wang, Rui, Yuen, Wendy, Takemura, Taichiro, Shelton, Kenneth, Taniuchi, Ichiro, Li, Yuan, Sodroski, Joseph, Littman, Dan R., Coffin, John M., Hughes, Stephen H., Unutmaz, Derya, Engelman, Alan, KewalRamani, Vineet N.

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Quantitative analysis of HIV-1 preintegration complexes by Engelman, Alan, Oztop, Ilker, Vandegraaff, Nick, Raghavendra, Nidhanapati K.

“…Retroviral replication proceeds through the formation of a provirus, an integrated DNA copy of the viral RNA genome. The linear cDNA product of reverse…”
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The functional interplay between TNPO3, CPSF6 and HIV-1 CA by Oztop, Ilker

“…Lentiviruses can infect postmitotic cells, indicative of a role for the nucleocytoplasmic transport machinery. Genome-wide RNA interference screens identified…”
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Viral latency and potential eradication of HIV-1 by Matreyek, Kenneth A, Oztop, Ilker, Freed, Eric O, Engelman, Alan

“…Although HAART can suppress plasma viral loads to undetectable levels, individuals infected with HIV-1 harbor latent reservoirs of integrated proviruses that…”
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