Search Results - "OZERCAN, Ibrahim H"
-
1
Melatonin suppresses cisplatin-induced nephrotoxicity via activation of Nrf-2/HO-1 pathway
Published in Nutrition & metabolism (12-01-2013)“…Cisplatin, one of the most effective and potent anticancer drugs, is used in the treatment of a wide variety of both pediatric and adult malignancies. However,…”
Get full text
Journal Article -
2
Non-clinical safety profile and pharmacodynamics of two formulations of the anti-sepsis drug candidate Rejuveinix (RJX)
Published in Biomedicine & pharmacotherapy (01-09-2021)“…Here, we demonstrate that the two distinct formulations of our anti-sepsis drug candidate Rejuveinix (RJX), have a very favorable safety profile in Wistar…”
Get full text
Journal Article -
3
RJX Improves Wound Healing in Diabetic Rats
Published in Frontiers in endocrinology (Lausanne) (02-06-2022)“…BackgroundWe recently reported the clinical safety profile of RJX, a well-defined intravenous GMP-grade pharmaceutical formulation of anti-oxidant and…”
Get full text
Journal Article -
4
Rejuveinix Shows a Favorable Clinical Safety Profile in Human Subjects and Exhibits Potent Preclinical Protective Activity in the Lipopolysaccharide-Galactosamine Mouse Model of Acute Respiratory Distress Syndrome and Multi‐Organ Failure
Published in Frontiers in pharmacology (10-11-2020)“…Background: New treatment platforms that can prevent acute respiratory distress syndrome (ARDS) or reduce its mortality rate in high-risk coronavirus disease…”
Get full text
Journal Article -
5
How can we use positron emission tomography/computed tomography more accurately for characterization of asbestos-related pleural thickening?
Published in Archives of medical science (2023)“…There is no consensus about the standardized uptake value maximum (SUV ) cut-off value to characterize pleural thickening worldwide. Sometimes, this causes…”
Get full text
Journal Article -
6
Effects of magnesium picolinate, zinc picolinate, and selenomethionine co-supplementation on reproductive hormones, and glucose and lipid metabolism-related protein expressions in male rats fed a high-fat diet
Published in Food chemistry. Molecular sciences (30-07-2022)“…•A high-fat diet intake leads to metabolic disorders such as obesity and diabetes.•Dietary supplementation of Mg, Zn, and Se can be used for the alleviation of…”
Get full text
Journal Article -
7
Lycopene Protects Against Spontaneous Ovarian Cancer Formation in Laying Hens
Published in Journal of cancer prevention (01-03-2018)“…Dietary intake of lycopene has been associated with a reduced risk of ovarian cancer, suggesting its chemopreventive potential against ovarian carcinogenesis…”
Get full text
Journal Article -
8
Anti-diabetic activity of chromium picolinate and biotin in rats with type 2 diabetes induced by high-fat diet and streptozotocin
Published in British journal of nutrition (28-07-2013)“…The objective of the present study was to evaluate anti-diabetic effects of chromium picolinate (CrPic) and biotin supplementations in type 2 diabetic rats…”
Get full text
Journal Article -
9
Ghrelin expression in normal kidney tissue and renal carcinomas
Published in Pathology, research and practice (01-01-2009)“…Ghrelin expression in cancers is either reduced/absent or increased depending on the organs involved. The aims of this study were to investigate: (i) whether…”
Get full text
Journal Article -
10
Genistein Prevents Development of Spontaneous Ovarian Cancer and Inhibits Tumor Growth in Hen Model
Published in Cancer prevention research (Philadelphia, Pa.) (01-03-2019)“…Genistein, the major isoflavone in soybean, has been reported to exert anticancer effects on various types of cancer including ovarian cancer; however, its…”
Get full text
Journal Article -
11
Protective effects of rosmarinic acid against azoxymethane‐induced colorectal cancer in rats
Published in Journal of biochemical and molecular toxicology (01-02-2022)“…Colorectal cancer (CRC) incidence is increasing gradually and has been become one of the most common cancers worldwide. Hence, it is important to discover…”
Get full text
Journal Article -
12
Effects of allyl isothiocyanate on insulin resistance, oxidative stress status, and transcription factors in high‐fat diet/streptozotocin‐induced type 2 diabetes mellitus in rats
Published in Journal of biochemical and molecular toxicology (01-07-2019)“…Allyl isothiocyanate (AITC), a dietary phytochemical found in some cruciferous vegetables, is commonly used as an antimicrobial, anticancer, and antioxidant…”
Get full text
Journal Article -
13
Obestatin is present in saliva: alterations in obestatin and ghrelin levels of saliva and serum in ischemic heart disease
Published in BMB reports (31-01-2008)“…Ghrelin and obestatin are a single gene products and are a multiple functional peptides that regulates energy homeostasis, and food intake. In the present…”
Get full text
Journal Article -
14
Ghrelin expression of endometrium hyperplasia and endometrioid carcinoma
Published in Gynecological endocrinology (01-03-2011)“…Background. Endometrium carcinoma ranks fourth among female carcinomas. Therefore, early diagnosis of endometrium pre-malignant lesions is emphasised, and…”
Get full text
Journal Article -
15
Brain death scintigraphy and pathology results in a rat model
Published in Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation (01-04-2014)“…Brain scintigraphy with Tc-99m-labeled diethylenetriaminopenta-acetic acid is a sensitive diagnostic method showing loss of cerebral blood flow that occurs…”
Get more information
Journal Article -
16
Ghrelin in plants: What is the function of an appetite hormone in plants?
Published in Peptides (New York, N.Y. : 1980) (01-07-2006)“…In the present work, we provide compelling evidence for the expression of a ghrelin-like peptide hormone that has only been associated with animals, in various…”
Get full text
Journal Article -
17
LFM-A13, a potent inhibitor of polo-like kinase, inhibits breast carcinogenesis by suppressing proliferation activity and inducing apoptosis in breast tumors of mice
Published in Investigational new drugs (01-06-2018)“…Summary The goals of the present study were to define the anticancer activity of LFM-A13 (α-cyano-β-hydroxy-β-methyl- N- (2,5-dibromophenyl)-propenamide), a…”
Get full text
Journal Article -
18
Prevention of DMBA-induced mammary gland tumors in mice by a dual-function inhibitor of JAK3 and EGF receptor tyrosine kinases
Published in Expert opinion on therapeutic targets (02-04-2020)“…: We tested the chemopreventive effect of WHI-P131 in side by side evaluation with the standard anti-breast cancer drug paclitaxel in the well-established…”
Get more information
Journal Article -
19
Effects of vitamin e, pentoxifylline and aprotinin on light-induced retinal injury
Published in Ophthalmologica (Basel) (01-01-2007)“…A considerable amount of clinical and experimental evidence exists suggesting the involvement of reactive oxygen species (ROS) in the etiology of light-induced…”
Get more information
Journal Article -
20
Effect of inositol -stabilized arginine silicate on arthritis in a rat model
Published in Food and chemical toxicology (01-03-2019)“…The purpose of this study was to test the effects of arginine-silicate-inositol complex (ASI), compared to a combination of the individual ingredients (A+S+I)…”
Get full text
Journal Article