Search Results - "OZAKI, Tomoya"
-
1
Type IIa RPTPs and Glycans: Roles in Axon Regeneration and Synaptogenesis
Published in International journal of molecular sciences (24-05-2021)“…Type IIa receptor tyrosine phosphatases (RPTPs) play pivotal roles in neuronal network formation. It is emerging that the interactions of RPTPs with glycans,…”
Get full text
Journal Article -
2
Primary Sulfonamide Functionalization via Sulfonyl Pyrroles: Seeing the N−Ts Bond in a Different Light
Published in Chemistry : a European journal (05-11-2021)“…Despite common occurrence in molecules of value, methods for transforming sulfonamides are distinctly lacking. Here we introduce easy‐to‐access sulfonyl…”
Get full text
Journal Article -
3
Close association of polarization and LC3, a marker of autophagy, in axon determination in mouse hippocampal neurons
Published in Experimental neurology (01-08-2022)“…The autophagy-lysosome pathway is a cellular clearance system for intracellular organelles, macromolecules and microorganisms. It is indispensable for cells…”
Get full text
Journal Article -
4
Glycan sulfation patterns define autophagy flux at axon tip via PTPRσ-cortactin axis
Published in Nature chemical biology (01-07-2019)“…Chondroitin sulfate (CS) and heparan sulfate (HS) are glycosaminoglycans that both bind the receptor-type protein tyrosine phosphatase PTPRσ, affecting axonal…”
Get full text
Journal Article -
5
Dermatan sulphate is an activating ligand of anaplastic lymphoma kinase
Published in Journal of biochemistry (Tokyo) (01-11-2021)“…Abstract Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase (RTK) that harbours a tyrosine kinase domain in its intracellular region and is…”
Get full text
Journal Article -
6
Axonal Regeneration by Glycosaminoglycan
Published in Frontiers in cell and developmental biology (16-06-2021)“…Like other biomolecules including nucleic acid and protein, glycan plays pivotal roles in various cellular processes. For instance, it modulates protein…”
Get full text
Journal Article -
7
Intracellular interplay between cholecystokinin and leptin signalling for satiety control in rats
Published in Scientific reports (20-07-2020)“…Cholecystokinin (CCK) and leptin are satiety-controlling peptides, yet their interactive roles remain unclear. Here, we addressed this issue using in vitro and…”
Get full text
Journal Article -
8
Infant satiety depends on transient expression of cholecystokinin‐1 receptors on ependymal cells lining the third ventricle in mice
Published in The Journal of physiology (01-03-2013)“…Key points In mammals, satiety‐controlling mechanisms develop before the switch from ingestive behaviour from milk suckling to regular food intake; however,…”
Get full text
Journal Article -
9
Functional Compensation between Cholecystokinin-1 and -2 Receptors in Murine Paraventricular Nucleus Neurons
Published in The Journal of biological chemistry (16-11-2012)“…Cholecystokinin (CCK) and its receptor subtypes CCK-1 and -2 have diverse homeostatic functions. CCK-1 and -2 receptors share a common phosphatidylinositol…”
Get full text
Journal Article -
10
First and second generation H1 histamine receptor antagonists produce different sleep-inducing profiles in rats
Published in European journal of pharmacology (15-05-2012)“…First generation H1 histamine receptor antagonists, such as d-chlorpheniramine (d-CPA) and diphenhydramine, produce drowsiness in humans. They are currently…”
Get full text
Journal Article -
11
Basigin deficiency prevents anaplerosis and ameliorates insulin resistance and hepatosteatosis
Published in JCI insight (22-10-2021)“…Monocarboxylates, such as lactate and pyruvate, are precursors for biosynthetic pathways, including those for glucose, lipids, and amino acids via the…”
Get full text
Journal Article -
12
Serotonin-2C receptor involved serotonin-induced Ca2+ mobilisations in neuronal progenitors and neurons in rat suprachiasmatic nucleus
Published in Scientific reports (17-02-2014)“…The hypothalamic suprachiasmatic nucleus (SCN), the central circadian pacemaker in mammals, undergoes serotonergic regulation, but the underlying mechanisms…”
Get full text
Journal Article -
13
Induction of prolonged, continuous slow‐wave sleep by blocking cerebral H1 histamine receptors in rats
Published in British journal of pharmacology (01-01-2012)“…BACKGROUND AND PURPOSE Classic H1 histamine receptor (H1R) antagonists are non‐selective for H1R and known to produce drowsiness. Modern antihistamines are…”
Get full text
Journal Article -
14
Effect of the presence of trophectoderm vesicles on blastocyst in relation to in vitro hatching, clinical pregnancy, and miscarriage rates
Published in Human cell : official journal of Human Cell Research Society (01-10-2016)“…Trophectoderm vesicles (TVs) are observed in some blastocysts that penetrate cells from the zona pellucida to the outer margin. Therefore, we compared this…”
Get full text
Journal Article -
15
Possible treatment of circadian sleep disorders using daily ketotifen administration
Published in Sleep and biological rhythms (01-01-2016)“…Classic H 1 histamine receptor (H 1 R) antagonists are currently used as over-the-counter sleep aids. However, their overdose administrations rather produce…”
Get full text
Journal Article -
16
Expression and activation of mitogen-activated protein kinase in the human endometrium during the menstrual cycle
Published in American journal of obstetrics and gynecology (01-11-2006)“…The purpose of this study was to investigate the fluctuation of expression and activation of mitogen-activated protein kinase in normal human endometrium…”
Get full text
Journal Article -
17
A BN-Benzvalene
Published in Journal of the American Chemical Society (11-09-2024)“…The synthesis and crystallographic characterization of BN-benzvalene, the first second-row heteroatom-containing benzvalene, is described. BN-benzvalenes are…”
Get full text
Journal Article -
18
Boron‐Nitrogen‐Containing Benzene Valence Isomers
Published in Chemistry : a European journal (01-10-2024)“…Benzene is one of the most ubiquitous structural motifs in chemistry. The valence isomers of benzene have also attracted synthetic chemists’ attention due to…”
Get full text
Journal Article -
19
Glypican-2 defines age-dependent axonal response to chondroitin sulfate
Published in Experimental neurology (01-08-2023)“…Axons of terminally differentiated neurons in the mammalian central nervous system (CNS) are unable to regenerate after dissection. One of the mechanisms…”
Get full text
Journal Article -
20
Expression of the type I interferon receptor and the interferon-induced Mx protein in human endometrium during the menstrual cycle
Published in Fertility and sterility (01-01-2005)“…To investigate the expression of the type I interferon receptor (IFNAR) and interferon-induced Mx protein (Mx) in normal human endometrium throughout the…”
Get more information
Journal Article