Search Results - "OWENS, R. C"

What is a new drug worth? An innovative model for performance-based pricing by Dranitsaris, G., Dorward, K., Owens, R.C., Schipper, H.

“…This article focuses on a novel method to derive prices for new pharmaceuticals by making price a function of drug performance. We briefly review current…”
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Clinical use of the fluoroquinolones by Owens, Jr, R C, Ambrose, P G

“…The appetite for modification to the basic quinolone nucleus has grown logarithmically since the first quinolone was employed in clinical practice. Important…”
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Design of a solution crystal growth crystallizer with a versatile electronic reciprocal motion control for a crystals holder by Batra, A. K., Carmichael-Owens, C. R., Simmons, M., Aggarwal, M. D., Lal, R. B.

“…A description of a modified crystallizer for growing large crystals from solutions along with the design of a versatile electronic reciprocating control system…”
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Risk Assessment for Antimicrobial Agent-Induced QTc Interval Prolongation and Torsades de Pointes by Owens Jr, Robert C.

“…Over the past several years a multitude of new pharmaceutical agents have been released to the market. Several of them were withdrawn altogether or their use…”
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In vitro synergistic activities of tobramycin and selected beta-lactams against 75 gram-negative clinical isolates by OWENS, R. C, BANEVICIUS, M. A, NICOLAU, D. P, NIGHTINGALE, C. H, QUINTILIANI, R

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Antimicrobial-Associated QT Interval Prolongation: Pointes of Interest by Goldstein, Ellie J. C., Owens, Robert C., Nolin, Thomas D.

“…Until recently, cardiac toxicity manifesting in the form of arrhythmias related to QT interval prolongation was uncommonly appreciated within the antimicrobial…”
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Comparative efficacies of levofloxacin and ciprofloxacin against Streptococcus pneumoniae in a mouse model of experimental septicaemia by Onyeji, Cyprian O, Bui, Khanh Q, Owens, Robert C, Nicolau, David P, Quintiliani, Richard, Nightingale, Charles H

“…The in vivo efficacies of levofloxacin and ciprofloxacin were compared against three clinical isolates of Streptococcus pneumoniae, using a mouse protection…”
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Pharmacokinetics of Rifapentine in Subjects Seropositive for the Human Immunodeficiency Virus: a Phase I Study by KEUNG, A. C.-F, OWENS, R. C, ELLER, M. G, WEIR, S. J, NICOLAU, D. P, NIGHTINGALE, C. H

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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An Epidemic, Toxin Gene–Variant Strain of Clostridium difficile by McDonald, L. Clifford, Killgore, George E, Thompson, Angela, Owens, Robert C, Kazakova, Sophia V, Sambol, Susan P, Johnson, Stuart, Gerding, Dale N

“…There have been increases in both the rate and the severity of C. difficile –associated disease. This report details the emergence of an epidemic strain,…”
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Oral bioavailability and pharmacokinetics of ciprofloxacin in patients with AIDS by OWENS, R. C, PATEL, K. B, BANEVICIUS, M. A, QUINTILIANI, R, NIGHTINGALE, C. H, NICOLAU, D. P

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Pharmacodynamics of ceftriaxone and cefixime against community-acquired respiratory tract pathogens by Owens, Robert C., Tessier, Pamela, Nightingale, Charles H., Ambrose, Paul G., Quintiliani, Richard, Nicolau, David P.

“…Over the last decade or so there has been a growing interest in routes of antimicrobial administration other than by the conventional intravenous route for…”
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Gatifloxacin-Associated Corrected QT Interval Prolongation, Torsades de Pointes, and Ventricular Fibrillation in Patients with Known Risk Factors by Bertino, Joseph S., Owens, Robert C., Carnes, Timothy D., Iannini, Paul B.

“…Drugs not commonly considered to be cardioactive agents have been reported to cause prolongation of the corrected QT interval with resultant torsades de…”
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Fluoroquinolone Pharmacodynamics by Drusano, G. L., Preston, S. L., Owens, Robert C., Ambrose, Paul G.

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Ceftibuten: An Overview by Owens, Robert C., Nightingale, Charles H., Nicolau, David P.

“…Ceftibuten is an orally active third‐generation cephalosporin that exhibits good microbiologic activity against many gram‐negative and select gram‐positive…”
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Antimicrobial pharmacodynamics by Ambrose, Jr, P G, Owens, R C, Grasela, D

“…The ultimate goal of antimicrobial therapy is to provide the best possible outcomes for patients. For this to occur, the clinician should be cognizant of many…”
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Purification and partial characterization of relaxin and relaxin precursors from the hamster placenta by RENEGAR, R. H, OWENS, C. R, CHALOVICH, J. M

“…Previous immunological studies have indicated that the molecular structure of hamster relaxin is quite different from that of porcine relaxin. In the present…”
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Comparison of azithromycin leukocyte disposition in healthy volunteers and volunteers with AIDS by McNabb, JoCarol, Owens, Robert C, Xuan, Dawei, Quintiliani, Richard, Nightingale, Charles H, Nicolau, David P

“…Azithromycin, has been proved to be effective in the treatment and prophylaxis of a wide variety of infections. While the penetration of azithromycin into a…”
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Hospital-Based Strategies for Combating Resistance by Owens, Robert C., Rice, Louis

“…Selective pressures generated by the indiscriminate use of β-lactam antibiotics have resulted in increased bacterial resistance across all β-lactams classes…”
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Comparison of bactericidal activity after multidose administration of clarithromycin, azithromycin, and cefuroxime axetil against Streptococcus pneumoniae by Lacy, Melinda K., Owens, Robert C., Xu, Xiqwei, Nicolau, David P., Quintiliani, Richard, Nightingale, Charles H.

“…The objective of this study was to compare the duration of serum bactericidal activity (SBA) for clarithromycin, azithromycin, and cefuroxime axetil in 12…”
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Torsades de Pointes Associated with Fluoroquinolones by Owens Jr, Robert C., Ambrose, Paul G.

“…Recent attention has been called to the interpretation of studies of antiinfective agents demonstrating effects on the QTc interval. It seems that the effects…”
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