Search Results - "OWEN, Art B"
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Outlier Detection Using Nonconvex Penalized Regression
Published in Journal of the American Statistical Association (01-06-2011)“…This article studies the outlier detection problem from the standpoint of penalized regression. In the regression model, we add one mean shift parameter for…”
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Genome-Wide Scan Informed by Age-Related Disease Identifies Loci for Exceptional Human Longevity
Published in PLoS genetics (01-12-2015)“…We developed a new statistical framework to find genetic variants associated with extreme longevity. The method, informed GWAS (iGWAS), takes advantage of…”
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Combining randomized field experiments with observational satellite data to assess the benefits of crop rotations on yields
Published in Environmental research letters (01-04-2022)“…With climate change threatening agricultural productivity and global food demand increasing, it is important to better understand which farm management…”
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Bi-Cross-Validation of the SVD and the Nonnegative Matrix Factorization
Published in The annals of applied statistics (01-06-2009)“…This article presents a form of bi-cross-validation (BCV) for choosing the rank in outer product models, especially the singular value decomposition (SVD) and…”
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Aging mice show a decreasing correlation of gene expression within genetic modules
Published in PLoS genetics (01-12-2009)“…In this work we present a method for the differential analysis of gene co-expression networks and apply this method to look for large-scale transcriptional…”
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LOW DISCREPANCY CONSTRUCTIONS IN THE TRIANGLE
Published in SIAM journal on numerical analysis (01-01-2015)“…Most quasi-Monte Carlo research focuses on sampling from the unit cube. Many problems, especially in computer graphics, are defined via quadrature over the…”
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Transcriptional profiling of aging in human muscle reveals a common aging signature
Published in PLoS genetics (01-07-2006)“…We analyzed expression of 81 normal muscle samples from humans of varying ages, and have identified a molecular profile for aging consisting of 250…”
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A Bayesian Framework for Combining Heterogeneous Data Sources for Gene Function Prediction (In Saccharomyces cerevisiae)
Published in Proceedings of the National Academy of Sciences - PNAS (08-07-2003)“…Genomic sequencing is no longer a novelty, but gene function annotation remains a key challenge in modern biology. A variety of functional genomics…”
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AGEMAP: a gene expression database for aging in mice
Published in PLoS genetics (01-11-2007)“…We present the AGEMAP (Atlas of Gene Expression in Mouse Aging Project) gene expression database, which is a resource that catalogs changes in gene expression…”
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Deterministic parallel analysis: an improved method for selecting factors and principal components
Published in Journal of the Royal Statistical Society. Series B, Statistical methodology (01-02-2019)“…Factor analysis and principal component analysis are used in many application areas. The first step, choosing the number of components, remains a serious…”
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Statistically Efficient Thinning of a Markov Chain Sampler
Published in Journal of computational and graphical statistics (03-07-2017)“…It is common to subsample Markov chain output to reduce the storage burden. Geyer shows that discarding k − 1 out of every k observations will not improve…”
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A transcriptional profile of aging in the human kidney
Published in PLoS biology (01-12-2004)“…In this study, we found 985 genes that change expression in the cortex and the medulla of the kidney with age. Some of the genes whose transcripts increase in…”
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CONFOUNDER ADJUSTMENT IN MULTIPLE HYPOTHESIS TESTING
Published in The Annals of statistics (01-10-2017)“…We consider large-scale studies in which thousands of significance tests are performed simultaneously. In some of these studies, the multiple testing procedure…”
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Bi-Cross-Validation for Factor Analysis
Published in Statistical science (01-02-2016)“…Factor analysis is over a century old, but it is still problematic to choose the number of factors for a given data set. We provide a systematic review of…”
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Backfitting for large scale crossed random effects regressions
Published in The Annals of statistics (01-02-2022)“…Regression models with crossed random effect errors can be very expensive to compute. The cost of both generalized least squares and Gibbs sampling can easily…”
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Scrambled Net Variance for Integrals of Smooth Functions
Published in The Annals of statistics (01-08-1997)“…Hybrids of equidistribution and Monte Carlo methods of integration can achieve the superior accuracy of the former while allowing the simple error estimation…”
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KARL PEARSON'S META-ANALYSIS REVISITED
Published in The Annals of statistics (01-12-2009)“…This paper revisits a meta-analysis method proposed by Pearson [Biometrika 26 (1934) 425–442] and first used by David [Biometrika 26 (1934) 1–11]. It was…”
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Extensible grids: uniform sampling on a space filling curve
Published in Journal of the Royal Statistical Society. Series B, Statistical methodology (01-09-2016)“…We study the properties of points in [0, 1]d generated by applying Hilbert's space filling curve to uniformly distributed points in [0, 1]. For deterministic…”
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A general characterization of optimal tie-breaker designs
Published in The Annals of statistics (01-06-2023)“…Tie-breaker designs trade off a measure of statistical efficiency against a short-term gain from preferentially assigning a binary treatment to subjects with…”
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