Search Results - "OVECHKINA, Y. Y"
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Unusual Antimicrotubule Activity of the Antifungal Agent Spongistatin 1
Published in Antimicrobial Agents and Chemotherapy (01-08-1999)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Gamma tubulin in plant cells
Published in Methods in Cell Biology (2001)“…Substantial progress has been made in cloning of plant γ-tubulin genes and immunolocalization of γ-tubulin. This chapter describes microtubule arrays in plants…”
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Book Chapter Journal Article -
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133P Novel fully human agonist antibodies against the T-cell costimulatory receptor CD27 shape adaptive anti-tumor immunity
Published in Annals of oncology (01-12-2021)Get full text
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Aurora B Regulates MCAK at the Mitotic Centromere
Published in Developmental cell (01-02-2004)“…Chromosome orientation and alignment within the mitotic spindle requires the Aurora B protein kinase and the mitotic centromere-associated kinesin (MCAK)…”
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MCAK associates with the tips of polymerizing microtubules
Published in The Journal of cell biology (09-05-2005)“…MCAK is a member of the kinesin-13 family of microtubule (MT)-depolymerizing kinesins. We show that the potent MT depolymerizer MCAK tracks (treadmills) with…”
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K-Loop Insertion Restores Microtubule Depolymerizing Activity of a "Neckless" MCAK Mutant
Published in The Journal of cell biology (25-11-2002)“…Unlike most kinesins, mitotic centromere-associated kinesin (MCAK) does not translocate along the surface of microtubules (MTs), but instead depolymerizes…”
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Abstract P6-14-17: In Vitro Evaluation of the Anti-EGFR Antibody Cetuximab and the Anti-HER2 Antibody Trastuzumab in a Panel of Human Tumor Cell Lines
Published in Cancer research (Chicago, Ill.) (15-12-2010)“…Abstract The epidermal growth factor receptors, EGFR (erbB-1) and HER2 (erbB-2), and their down stream signaling events promote tumor growth and survival in a…”
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Unconventional Motoring: An Overview of the Kin C and Kin I Kinesins
Published in Traffic (Copenhagen, Denmark) (01-06-2003)“…All kinesins share a conserved core motor domain implying a common mechanism for generating force from ATP hydrolysis. How is it then that kinesins exhibit…”
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MCAK, a Kin I kinesin, increases the catastrophe frequency of steady‐state HeLa cell microtubules in an ATP‐dependent manner in vitro
Published in FEBS letters (13-08-2004)“…Mitotic‐centromere‐associated kinesin (MCAK) is a member of the KIN I (internal motor domain) subfamily of kinesin related proteins. MCAK and its homologues…”
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Abstract B35: High-throughput cell line profiling for identification of anticancer drug sensitivity and resistance biomarkers with OncoPredictor
Published in Clinical cancer research (15-07-2010)“…Abstract Tumor derived cell lines have been in use for cancer drug profiling as evidenced by the establishment of NCI-60 panel as a drug discovery tool in…”
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Spindle formation in Aspergillus is coupled to tubulin movement into the nucleus
Published in Molecular biology of the cell (01-05-2003)“…In many important organisms, including many algae and most fungi, the nuclear envelope does not disassemble during mitosis. This fact raises the possibility…”
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Phosphorylation of the CARMA1 Linker Controls NF-κB Activation
Published in Immunity (Cambridge, Mass.) (01-12-2005)“…PKC isoforms and CARMA1 play crucial roles in immunoreceptor-dependent NF-κB activation. We tested whether PKC-dependent phosphorylation of CARMA1 directly…”
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Abstract 4845: Tumor cell line profiling of eighteen cancer therapeutics to evaluate relationships between tumor genotypes and cancer cell sensitivities
Published in Cancer research (Chicago, Ill.) (15-04-2011)“…Abstract In vitro cellular response profiling of tumor human cell lines has become a widely used approach for the targeted cancer therapeutics development…”
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Microtubule destabilizing activity of a kinesin related protein, MCAK: Mechanism and regulation
Published 01-01-2004“…Microtubule dynamics are essential for multiple cellular processes, such as chromosome segregation, cell morphogenesis and cell motility. However, our…”
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Dissertation